Amaphepha amasha e-glyphosate akhomba "ekuphuthumeni" kocwaningo olwengeziwe ngomthelela wamakhemikhali empilweni yomuntu

Phrinta imeyili Ungahlukıselana Ephathwayo

Amaphepha esayensi amasha asanda kushicilelwa akhombisa ubuningi bokutholakala kokhula olubulala ukhula i-glyphosate kanye nesidingo sokuqonda kangcono umthelela ovezwa umuthi wokubulala izinambuzane odumile ongahle ube nawo empilweni yomuntu, kubandakanya nempilo yegciwane le-microbiome.

In elinye lamaphepha amasha, Abaphenyi abavela eNyuvesi yaseTurku eFinland bathi bakwazile ukuthola, "ngokulinganisela okulindelekile," ukuthi cishe amaphesenti angama-54 ezinhlobo ezisengxenyeni ye-gut microbiome yomuntu "angazwela" ku-glyphosate. Abaphenyi bathi basebenzise indlela entsha ye-bioinformatics ukwenza okutholakele.

Nge "ingxenye enkulu" yamagciwane asesiswini i-microbiome esengozini ye-glyphosate, ukutholwa kwe-glyphosate "kungathinta kakhulu ukwakheka kwe-gut microbiome yomuntu," kusho ababhali ephepheni labo, elishicilelwe kule nyanga Ijenali Yezinto Eziyingozi.

Amagciwane asemathunjini omuntu afaka izinhlobo ezahlukahlukene zamagciwane kanye nesikhunta futhi kukholelwa ukuthi kunomthelela ekusebenzeni komzimba kanye nezinye izinqubo ezibalulekile. Ama-microbiomes emathunjini angenampilo akholelwa ososayensi abathile ukuthi banikela ezinhlotsheni zezifo.

"Yize imininingwane yezinsalela ze-glyphosate ezinhlelweni zomgudu womuntu isashoda, imiphumela yethu iphakamisa ukuthi izinsalela ze-glyphosate zinciphisa ukwehluka kwamagciwane futhi zilinganise ukwakheka kwezinhlobo zamagciwane emathunjini," kusho ababhali. "Singacabanga ukuthi ukutholakala isikhathi eside ezinsaleleni ze-glyphosate kuholela ekubuseni kwamagciwane amelana nomphakathi wamagciwane."

Ukukhathazeka ngomthelela we-glyphosate kumgudu womuntu we-microbiome kusuka eqinisweni lokuthi i-glyphosate isebenza ngokukhomba i-enzyme eyaziwa njenge-5-enolpyruvylshikimate-3-phosphate synthase (EPSPS.) Le enzyme ibalulekile ekwakhiweni kwama-amino acid abalulekile.

“Ukuthola umthelela wangempela we-glyphosate ku-gut gut microbiota nakwezinye izinto eziphilayo, kudingeka izifundo ezengeziwe zokuveza izinsalela ze-glyphosate ekudleni, ukuthola imiphumela ye-glyphosate emsulwa nokwakhiwa kwezentengiselwano kuma-microbiomes nokuhlola ukuthi i-EPSPS yethu ingakanani izimpawu ze-amino acid zibikezela ukuthi amagciwane angabanjwa yi-glyphosate in vitro kanye nezimo zomhlaba wangempela, ”kuphetha ababhali bephepha elisha.

Ngaphezu kwabaphenyi abayisithupha abavela eFinland, omunye wababhali bephepha ubambisene nomnyango we-biochemistry kanye ne-biotechnology eRovira i Virgili University, eTarragona, eCatalonia, eSpain.

“Imiphumela yezempilo yomuntu ayinqunywa esifundweni sethu. Kodwa-ke, ngokuya ngocwaningo lwangaphambilini… siyazi ukuthi ushintsho ku-gut gut microbiome lungaxhunyaniswa nezifo eziningi, ”kusho umcwaningi wase-University of Turku uPere Puigbo enkulumweni abe nayo.

"Ngiyethemba ukuthi ucwaningo lwethu luvula umnyango wokuqhubeka nokuhlola, ku-in-vitro nasensimini, kanye nezifundo ezenzelwe inani labantu ukuze kukalwe umphumela ukusetshenziswa kwe-glyphosate okunayo kubantu nakwezinye izinto eziphilayo," kusho uPuigbo.

Kwethulwe ku-1974

I-Glyphosate isithako esisebenzayo kuma-Roundup herbicides kanye namakhulu eminye imikhiqizo yokubulala ukhula edayiswa emhlabeni jikelele. Yethulwa njengombulali wokhula nguMonsanto ngonyaka we-1974 futhi yakhula yaba umuthi wokubulala ukhula osetshenziswa kakhulu ngemuva kokwethulwa kukaMonsanto ngeminyaka yama-1990s yezitshalo ezakhiwe ngezakhi zofuzo ukubekezelela ikhemikhali. Izinsalela ze-glyphosate zivame ukutholakala ekudleni nasemanzini. Ngenxa yalokho, izinsalela zivame ukutholakala emchameni wabantu abavezwe ku-glyphosate ngokudla kanye / noma ngokufaka isicelo.

Abalawuli baseMelika kanye nomnikazi weMonsanto uBayer AG bagcina ukuthi akukho ukukhathazeka kwezempilo yabantu ngokuvezwa kwe-glyphosate lapho imikhiqizo isetshenziswa njengoba kuhlosiwe, kufaka phakathi okusele ekudleni.

Umzimba wocwaningo ophikisana nalezo zimangalo uyakhula, noma kunjalo. Ucwaningo ngemithelela engaba khona ye-glyphosate ku-gut microbiome alucishe luqine njengezincwadi ezihlanganisa i-glyphosate nomdlavuza, kepha luyindawo ososayensi abaningi bayaphenya.

Ngokuhlobene kancane iphepha eshicilelwe kule nyanga, iqembu labaphenyi baseWashington State University naseDuke University bathi bathole ukuxhumana phakathi kwamazinga amabhaktheriya nesikhunta emapheshana emathunjini ezingane namakhemikhali atholakala emakhaya abo. Abaphenyi abazange babheke i-glyphosate ngokuqondile, kodwa babenjalo wethukile ukuthola ukuthi izingane ezinamazinga aphezulu amakhemikhali avamile asendlini egazini lazo zibonise ukwehla kwenani nokwehluka kwamagciwane abalulekile emathunjini awo.

IGlyphosate emchameni

An iphepha elengeziwe lesayensi kushicilelwe kule nyanga kugcizelele isidingo sedatha engcono nengaphezulu uma kukhulunywa ngokuvezwa kwe-glyphosate nezingane.

Leli phepha, lishicilelwe ephephabhukwini Health Environmental ngabaphenyi abavela ku-Institute for Translational Epidemiology e-Icahn School of Medicine eNtabeni iSinayi eNew York, kungumphumela wokubuyekezwa kwezincwadi zezifundo eziningi ezibika amanani wangempela we-glyphosate kubantu.

Ababhali bathi bahlaziye izifundo ezinhlanu ezishicilelwe eminyakeni emibili edlule zibika amazinga e-glyphosate alinganiswa kubantu, kufaka phakathi ucwaningo olulodwa lapho kukalwa khona amazinga e-urinary glyphosate ezinganeni ezihlala emaphandleni aseMexico. Ezinganeni ezingama-192 ezihlala endaweni yase-Agua Caliente, amaphesenti angama-72.91 ayenezinga le-glyphosate elitholakalayo emchameni wazo, futhi zonke izingane ezingama-89 ezihlala e-Ahuacapán, eMexico, zazinamazinga atholakalayo we-pesticide emchameni wazo.

Noma ufaka izifundo ezingeziwe, kukonke, kunemininingwane embalwa mayelana namazinga e-glyphosate kubantu. Izifundo emhlabeni jikelele zingabantu abangu-4,299 kuphela, kubandakanya nezingane ezingama-520, kusho abacwaningi.

Ababhali baphethe ngokuthi okwamanje akunakwenzeka ukuqonda "ubudlelwano obungahle bube khona" phakathi kokuvezwa kwe-glyphosate nezifo, ikakhulukazi ezinganeni, ngoba ukuqoqwa kwedatha emazingeni okuvezwa kwabantu kunqunyelwe futhi akujwayelekile.

Baphawule ukuthi yize bekushoda imininingwane eqinile mayelana nemithelela ye-glyphosate ezinganeni, inani lezinsalela ze-glyphosate ezivunyelwe ngokusemthethweni ngabalawuli be-US ekudleni lenyuke kakhulu kule minyaka edlule.

"Kunezikhala ezincwadini ezibhalwe nge-glyphosate, futhi lezi zikhala kufanele zigcwaliswe ngokuphuthuma okuthile, uma kubhekwa ukusetshenziswa okukhulu kwalo mkhiqizo nokuba khona kwawo yonke indawo," kusho umbhali u-Emanuela Taioli.

Izingane zisengcupheni yokuthola izidalwa ezibulala imvelo futhi ukulandelela ukutholakala kwemikhiqizo efana ne-glyphosate ezinganeni “kuyinto ebaluleke kakhulu kwezempilo yomphakathi,” ngokusho kwabalobi bephepha.

"Njenganoma iyiphi ikhemikhali, kunezinyathelo eziningi ezibandakanyekile ekuhloleni ubungozi, okubandakanya ukuqoqa imininingwane mayelana nokuvezwa kwabantu, ukuze amazinga aletha ukulimala kubantu noma ezilwaneni ezilwaneni angaqhathaniswa namazinga okuvezwa ajwayelekile," kubhala ababhali.

“Kodwa-ke phambilini sikhombisile ukuthi imininingwane ngokuvezwa kwabantu kubasebenzi nakubantu jikelele incane kakhulu. Kunezinye izikhala zolwazi ezikhona kulo mkhiqizo, ngokwesibonelo imiphumela ku-genotoxicity yayo kubantu inqunyelwe. Impikiswano eqhubekayo mayelana nemiphumela yokuchayeka kwe-glyphosate yenza ukuthi amazinga okuchayeka emphakathini jikelele kube yinkinga ecindezelayo yezempilo yomphakathi, ikakhulukazi kulabo abasengozini enkulu.

Ababhali bathe ukuqapha amazinga we-urinary glyphosate kufanele kwenziwe kubantu abaningi.

“Siyaqhubeka nokuphakamisa ukuthi ukufakwa kwe-glyphosate njengokuvezwa okulinganisiwe ezifundweni ezimele izwe lonke njengeNational Health and Nutrition Examination Survey kuzovumela ukuqonda kangcono izingozi ezingase zibangelwe yi-glyphosate futhi kuvumele ukuqashwa okungcono kwalabo okungenzeka badalulwe futhi labo abasengozini yokuchayeka kalula, ”babhala.

INkantolo Ephakeme yaseCalifornia iphika ukubuyekezwa kokulahleka kwecala leMonsanto Roundup

Phrinta imeyili Ungahlukıselana Ephathwayo

INkantolo Ephakeme yaseCalifornia ayizukubuyekeza ukunqoba kwecala lowesilisa waseCalifornia elanqoba iMonsanto, laphinde lahlasela umnikazi waseMonsanto waseGerman, uBayer AG.

The isinqumo sokwenqaba ukubuyekezwa ecaleni likaDewayne “Lee” Johnson umaka okwakamuva ochungechungeni lokulahlekelwa yinkantolo ngenxa Bayer njengoba izama ukuqeda izindawo zokuhlala nabamangali ababalelwa ku-100,000 XNUMX abathi ngamunye noma abathandekayo bakhe bathuthukisa i-non-Hodgkin lymphoma kusukela ekuchayekeni kwe-Roundup nabanye ababulali bokhula baseMonsanto. Amajaji ekuhlolweni ngakunye kwezintathu okubanjwe kuze kube manje awatholanga lokho kuphela kwenkampani ukhula lwe-glyphosate-based kubangela umdlavuza kepha nokuthi uMonsanto uchithe amashumi eminyaka efihla izingozi.

“Sidumele ngesinqumo seNkantolo sokungabuyekezi isinqumo senkantolo yokudlulisa enkantolo ephakathi Johnson sizobheka nezinqumo zethu zomthetho ukuze siqhubeke nokubuyekeza leli cala, ”kusho uBayer esitatimendeni.  

Inkampani kaMiller, Inkampani yabameli bakaJohnson eseVirginia, ithe isinqumo seNkantolo Ephakeme yaseCalifornia siphikile “umzamo kaMonsanto wakamuva wokweqa umthwalo” ngokudala umdlavuza kaJohnson.

“Amajaji amaningi manje asekuqinisekisile ukuvumelana ngazwi linye kwejaji ukuthi iMonsanto ifihle ngenhloso ingozi yomdlavuza kaRoundup futhi yabangela uMnu. Johnson ukuba abe nomdlavuza obulalayo. Isikhathi sesifikile sokuthi iMonsanto iqede izicelo zayo ezingenasisekelo futhi ikhokhele uMnu Johnson imali emukweleta yona, ”kusho le nkampani.

Ijaji elavumelana ngazwi linye elatholakala ngo-Agasti 2018 lokuthi ukuvezwa kwemithi yokubulala ukhula kaMonsanto kwabangela ukuthi uJohnson athuthukise uhlobo olubulalayo lwe-non-Hodgkin lymphoma. Ijaji labuye lathola ukuthi iMonsanto yenza ukufihla ubungozi bemikhiqizo yayo ngokuziphatha ngendlela emangazayo kangangokuba inkampani kufanele ikhokhele uJohnson $ 250 million ngokulimala kokujezisa ngaphezu kuka- $ 39 wezigidi kumonakalo odlule nowesikhathi esizayo.

Ngemuva kokudluliswa kwesinqumo esivela eMonsanto, ijaji lecala lanciphisa imali eyizigidi ezingama- $ 289 kuya ku- $ 78 million. Inkantolo yokudlulisa amacala ibe isinqamula lo mklomelo waba ngu- $ 20.5 million, icaphuna iqiniso lokuthi uJohnson kwakulindeleke ukuthi aphile isikhashana nje.

Inkantolo yokudlulisa amacala ithe yehlise indondo yomonakalo ngaphandle kokuthola kwakukhona ubufakazi "obuningi" bokuthi i-glyphosate, kanye nezinye izithako emikhiqizweni yakwaRoundup, yabangela umdlavuza kaJohnson nokuthi "kwakukhona ubufakazi obuqand 'ikhanda bokuthi uJohnson wahlupheka, futhi usazoqhubeka nokuhlupheka impilo yakhe yonke, ubuhlungu obukhulu nokuhlupheka. ”

Bobabili uMonsanto noJohnson bafuna ukubuyekezwa yiNkantolo Ephakeme yaseCalifornia, uJohnson ecela ukubuyiselwa umklomelo omkhulu wokulimala kanti uMonsanto ufuna ukuguqula isinqumo senkantolo.

IBayer ifinyelele ezindaweni zokuhlala nezinkampani ezimbalwa ezihola phambili zabameli ezimele isabelo esikhulu sezimangalo ezilethwe iMonsanto. NgoJuni, iBayer yathi izonikeza u- $ 8.8 billion kuya ku- $ 9.6 billion ukuxazulula icala.

Inkantolo yokudlulisa amacala isekela ukuhlolwa kwesifo somdlavuza se-Roundup esivikela iMonsanto

Phrinta imeyili Ungahlukıselana Ephathwayo

Kokunye ukulahleka kwenkantolo komnikazi weMonsanto uBayer AG, inkantolo yokudlulisa amacala yenqabile umzamo wenkampani wokuguqula ukunqoba kwecala okwenziwe ngumgcini wesikole saseCalifornia owasola ukuthi ukutholakala kwemithi yokubulala uketshezi iMonsanto glyphosate kwamenza waba nomdlavuza, yize inkantolo yathi umonakalo kufanele usike ku- $ 20.5 million.

Inkantolo Yokudlulisa Amacala Yesifunda Sokuqala Sokudlulisa Amacala eCalifornia kusho uMsombuluko ukuthi izimpikiswano zikaMonsanto zazingacabangi futhi uDewayne “Lee” Johnson wayenelungelo lokuqoqa imali eyizigidi ezingama- $ 10.25 kumonakalo wesinxephezelo kanye nezinye izigidi ezingama- $ 10.25 kumonakalo wokujezisa. Lokho kwehle kusamba semali engu- $ 78 million esehlulelwe yijaji.

"Ngokubona kwethu, uJohnson wethule ubufakazi obuningi - futhi obukhulu - bokuthi i-glyphosate, kanye nezinye izithako zemikhiqizo yeRoundup, yimbangela yomdlavuza wakhe," kusho inkantolo. "Isazi ngemuva kokuthi isazi sinikeze ubufakazi bokuthi imikhiqizo ye-Roundup iyakwazi ukudala i-non-Hodgkin's lymphoma ... futhi yabangela umdlavuza kaJohnson ikakhulukazi."

Inkantolo yaqhubeka yathi “kwakukhona ubufakazi obuqand 'ikhanda bokuthi uJohnson wahlupheka, futhi usazoqhubeka nokuhlupheka impilo yakhe yonke, ubuhlungu obukhulu nokuhlupheka.”

Inkantolo ithe impikiswano kaMonsanto yokuthi okutholwe yisayensi mayelana nezixhumanisi ze-glyphosate nomdlavuza yakha "umbono omncane" awusekelwa.

Kuyaphawuleka ukuthi inkantolo yokudlulisa amacala yanezela ukuthi bekufanele kulinyazwe isijeziso ngoba kunobufakazi obanele bokuthi uMonsanto wenza “ngamabomu nangokungahloniphi ukuphepha kwabanye.”

UMike Miller, inkampani yakhe yabameli baseVirginia emele uJohnson ngesikhathi kuqulwa icala kanye neBaum Hedlund Aristei & Goldman firm yaseLos Angeles, uthe uthokozile ngesiqinisekiso senkantolo sokuthi uJohnson waba nomdlavuza ngokusebenzisa kwakhe iRoundup nokuthi inkantolo yaqinisekisa umklomelo wesijeziso umonakalo ngenxa “yokuziphatha kabi ngamabomu kukaMonsanto.”

“UMnu Johnson uqhubeka nokuhlushwa ukulimala kwakhe. Siyaziqhenya ngokulwela uMnu Johnson nokulandela kwakhe ubulungiswa, ”kusho uMiller.

IMonsanto ikweleta inzalo yaminyaka yonke ngesilinganiso samaphesenti ayi-10 kusuka ngo-Ephreli we-2018 ize ikhokhe isinqumo sokugcina.

Ukwehliswa komonakalo kuhlanganiswe nengxenye yokuthi odokotela batshele uJohnson ukuthi umdlavuza wakhe awupheli futhi akulindelekile ukuthi aphile isikhathi eside kakhulu. Inkantolo ivumelane neMonsanto ukuthi ngenxa yokuthi umonakalo okhokhelwayo wenzelwe ukunxephezela ubuhlungu besikhathi esizayo, ukuhlupheka kwengqondo, ukulahlekelwa yinjabulo yempilo, ukukhubazeka emzimbeni, njll. kumele yehliswe.

UBrent Wisner, ongomunye wabameli bakaJohnson ecaleni lakhe, uthe ukwehliswa komonakalo kuwumphumela "wephutha elijulile emthethweni waseCalifornia."

"Ngokuyisisekelo, umthetho waseCalifornia awumvumeli ummangali ukuthi alulame isikhathi esifushane sokuphila," kusho uWisner. “Lokhu kuvuza kahle ummangalelwa ngokubulala ummangali, kunokumlimaza nje. Kuwumsangano. ”

Ukugqama kokuziphatha kukaMonsanto

Kwakuyizinyanga ezimbili nje ngemuva kokuba iBayer ithenge iMonsanto, ngo-Agasti 2018, lapho ijaji elilodwa unikeze uJohnson u- $ 289 million, kufaka phakathi amaRandi ayizigidi ezingama-250 emonakalweni wokujeziswa, ukuthola ukuthi akubulali nje kuphela imithi yokubulala ukhula kaMonsanto ebangele ukuthi uJohnson athuthukise i-non-Hodgkin lymphoma, kepha nokuthi inkampani ibazi ubungozi bomdlavuza futhi yehluleka ukuxwayisa uJohnson. Icala lalibandakanya imikhiqizo emibili yokubulala ukhula iMonsanto glyphosate - iRoundup neRanger Pro.

Ijaji lecala lehlisa isinqumo esiphelele saba ngama- $ 78 million kodwa uMonsanto wasidlulisa isamba esincishisiwe. UJohnson cross unxuse ukuthi kubuyiswe isinqumo sango- $ 289 million.

Icala likaJohnson lambozwa abezindaba emhlabeni jikelele futhi labeka obala ekuziphatheni okungabazekayo kweMonsanto. Abameli bakaJohnson banikeze ama-jurors ama-imeyili enkampani yangaphakathi namanye amarekhodi akhombisa ososayensi baseMonsanto bexoxa ngamaphepha esayensi abhala ghost ukuze bazame ukuxhasa ukusekelwa kokuphepha kwemikhiqizo yenkampani, kanye nezindlela zokuxhumana ezinemininingwane yokuhlambalaza abagxeki, nokuqeda ukuhlolwa kukahulumeni ubuthi be-glyphosate, ikhemikhali eliyisihluthulelo emikhiqizweni kaMonsanto.

Imibhalo yangaphakathi ibuye ikhombise ukuthi iMonsanto ibilindele ukuthi i-International Agency for Research on Cancer ihlukanise i-glyphosate njenge-carcinogen yabantu okungenzeka noma kungenzeka ngoMashi ka-2015 (ukuhlukaniswa kwaba njenge-carcinogen okungenzeka kube khona) futhi yahlela isu kusengaphambili lokuhlambalaza ososayensi bomdlavuza ngemuva bakhipha ukuhlukaniswa kwabo.

Amashumi ezinkulungwane zabamangali afake icala kuMonsanto enza izimangalo ezifana nezikaJohnson, kanti sekunezilingo ezimbili ezengeziwe selokhu kwaqulwa icala likaJohnson. Zombili lezo zilingo nazo ziholele ekutheni kukhishwe izinqumo ezinkulu ngokumelene neMonsanto. Bobabili nabo bangaphansi kwesikhalazo.

NgoJuni, iBayer yathi isifinyelele ku-  isivumelwano sokuxazulula nabameli abamele amaphesenti angama-75 wabantu abacishe bafike ku-125,000 abafakelwe izicelo futhi abasazofakwa izicelo ezaqalwa ngabamangali baseMelika abasola ukutholakala kweM Roundanto kaMonsanto ngokuthuthukisa kwabo i-non-Hodgkin lymphoma. IBayer ithe izohlinzeka ngo- $ 8.8 billion kuya ku- $ 9.6 billion ukuxazulula icala. Kepha abameli abamele ngaphezulu kwabamangaleli abangaphezulu kuka-20,000 XNUMX bathi abavumanga ukuvumelana neBayer futhi lawo macala kulindeleke ukuthi aqhubeke nokusebenza ngendlela yohlelo lwenkantolo.

Esitatimendeni esikhishwe ngemuva kwesinqumo senkantolo, uBayer uthe kusekela ukuphepha kukaRoundup: “Isinqumo senkantolo yokudlulisa amacala ukwehlisa umonakalo okhokhelwayo nesijeziso siyisinyathelo esiqonde ngqo, kepha siyaqhubeka nokukholelwa ukuthi isinqumo sejaji kanye nomonakalo imiklomelo ayihambisani nobufakazi obusecaleni nasenkantolo. IMonsanto izobheka izinketho zayo ezingokomthetho, kufaka phakathi nokufaka isicelo sokuphikisa iNkantolo Ephakeme yaseCalifornia. ”