Ukuphishekela iqiniso nokwenza izinto obala kwezempilo yomphakathi

Amaphepha eMonsanto - Izimfihlo Eziyingozi, Ukukhohlakala Kwebhizinisi, kanye Nokufuna Komuntu Ubulungiswa

Phrinta imeyili Ungahlukıselana Ephathwayo

Incwadi entsha yoMqondisi Wezocwaningo wase-USRTK uCarey Gillam iphumile manje futhi iqoqa izibuyekezo ezikhanyayo. Nayi incazelo emfushane yencwadi evela kumshicileli Isiqhingi Press:

U-Lee Johnson wayeyindoda enamaphupho alula. Konke ayekufuna kwakuwumsebenzi ozinzile kanye nekhaya elihle lomkakhe nezingane, okungcono kunempilo enzima ayaziyo esakhula. Wayengakaze acabange ukuthi angaba ubuso bokubambana kukaDavid noGoliyathi ngokulwa nesinye sezikhondlakhondla zezinkampani ezinamandla kakhulu emhlabeni. Kodwa ingozi yasemsebenzini yashiya uLee efakwe ikhemikhali enobuthi futhi ebhekene nomdlavuza obulalayo owaguqula impilo yakhe yabhekisa phansi. Ku-2018, umhlaba ubukele njengoba uLee ebhekwe phambili kwezimpi ezisemthethweni ezinkulu kakhulu emlandweni wakamuva.

Amaphepha eMonsanto yindaba yangaphakathi yecala elibalulekile likaLee Johnson elibhekene neMonsanto. KuLee, leli cala lalingumjaho ophikisana newashi, nodokotela babikezela ukuthi ngeke aphile isikhathi eside ngokwanele ukuthi angathatha ukuma kofakazi. Eqenjini le-eclectic labammeli abancane, abanesifiso sokumela, bekuyindaba yokuziqhenya kobungcweti nokuzibeka engcupheni komuntu siqu, nezigidi zamadola abo kanye nodumo olutholwe kanzima kulayini.

Ngamandla okulandisa athintekayo, Amaphepha eMonsanto ithatha abafundi ekusithekeni kwempi yomthetho ekhathazayo, ibuyisa ikhethini ebuthakathakeni bohlelo lwenkantolo yaseMelika nobude abameli abazoya kulo ukulwa nobubi bezinkampani futhi bathole ubulungiswa kubathengi.

Bona okuningi mayelana ne- bhuka lapha. Thenga incwadi ku AmazonBarnes & Noble, umshicileli Isiqhingi Press noma abathengisi bezincwadi abazimele.

Izibuyekezo

“Indaba enamandla, ixoxwa kahle, nomsebenzi omuhle wobuntatheli bokuphenya. UCarey Gillam ubhale incwadi ephoqelelayo kusukela ekuqaleni kuze kube sekugcineni, mayelana nezimpi zomthetho ezibaluleke kakhulu esikhathini sethu. ” - Lukas Reiter, umkhiqizi omkhulu we-TV nomlobi we "The Blacklist," "The Practice," ne "Boston Legal"

“Amaphepha eMonsanto ahlanganisa isayensi nenhlekelele yabantu nedrama yasenkantolo ngesitayela sikaJohn Grisham. Kuyindaba yokukhohlakala kwezinkampani ngezinga elikhulu - isambulo esethusayo sokuhaha komkhakha wamakhemikhali, ukuzikhukhumeza, nokunganaki impilo yabantu nempilo yeplanethi yethu. Kumele kufundwe. ” - UPhilip J. Landrigan, MD, uMqondisi, uHlelo Lwezempilo Yomphakathi Lomhlaba Wonke kanye neCommon Good, iBoston College

"Intatheli emnkantshubomvu ephenya uCarey Gillam utshela udaba lukaJohnson encwadini yakhe yakamuva ethi," The Monsanto Papers, "i-akhawunti esheshayo, ethintekayo yokuthi ingcebo yeMonsanto neBayer yashintsha kanjani kakhulu esikhathini esifushane kangaka. Ngaphandle kodaba oludingidwayo - isayensi nenkambiso yomthetho eyinkimbinkimbi - "Amaphepha eMonsanto" ukufundwa okuhlabahlosile okunikeza incazelo ekulula ukuyilandela yokuthi lamacala aqhubeka kanjani, amajaji afinyelela kanjani esinqumweni sawo nokuthi kungani iBayer ibonakala ngathi, empeleni , ngiphakamisa ifulegi elimhlophe manje. ” - St Louis Post-Dispatch

“Umbhali wakha icala eligculisayo lokuthi iMonsanto ibikuthanda kakhulu ukuvikela isithunzi senkomo yayo engukheshi kunokulalela ubufakazi besayensi ngezinto zayo eziyingozi. UGillam ulunge kakhulu ekunikezeni izinto eziyinkimbinkimbi zobuntu obusemthethweni, okunezela obunye ubuntu endabeni kaJohnson… Ukwehliswa okugunyaziwe kwenhlangano okusobala ukuthi ayinandaba nempilo yomphakathi. ” - UKirkus

“UGillam ulandisa ngokubalwa kwesikhashana nenkampani enkulu imikhiqizo yayo ebimakethwa njengephephile kusukela ngawo-1970. Njengokubhekwa kokukhohlakala kwezinkampani kanye nokuqondiswa komthetho ezimweni ezibucayi, incwadi kaGillam iveza isidingo sokuvikelwa nokuphepha kwabathengi. ” - Uhlu lwezincwadi

“Kufundwe kahle, kuphendulwa ikhasi. Ngangikhathazeke ngokuphelele ngenkohliso, ukuhlanekezelwa, nokuntuleka kwenkambiso yenkampani. ” - ULinda S. Birnbaum, Owabe enguMqondisi, Isikhungo Sikazwelonke Sezesayensi Yezemvelo kanye noHlelo Lukazwelonke Lwezidakamizwa, kanye neScholar eResidence, eDuke University

"Incwadi enamandla ekhanyisa iMonsanto nabanye osekuyisikhathi eside bengathintwa!"
- UJohn Boyd Jr., uMsunguli noMongameli, iNational Black Farmers Association

Mayelana Nombhali

Intatheli ephenyayo uCarey Gillam uchithe iminyaka engaphezu kwengu-30 ebika ngeMelika yezinkampani, kubandakanya neminyaka eyi-17 esebenzela i-Reuters international agency. Incwadi yakhe yango-2017 emayelana nobungozi bezibulala-zinambuzane, iWhitewash: The Story of a Weed Killer, Cancer, and the Corruption of Science, iwine i-2018 Rachel Carson Book Award evela kwi-Society of Environmental Journalists futhi isiyingxenye yekharikhulamu kwezempilo eziningana zemvelo zaseyunivesithi. izinhlelo. UGillam njengamanje unguMqondisi Wokucwaninga weqembu labathengi elingenzi nzuzo i-US Right to Know futhi ubhala njengomnikeli we I-Guardian.

Uhlelo lukaBayer lokuxazulula izimangalo zomdlavuza zeRoundup zesikhathi esizayo lubhekene nokuphikiswa okukhulu

Phrinta imeyili Ungahlukıselana Ephathwayo

Izinkampani eziningi zezomthetho zase-US sezisungule umfelandawonye wokulwa ne- $ 2 billion entsha isiphakamiso sokuhlala ngumnikazi weMonsanto uBayer AG ohlose ukuqukatha isikweletu esiqhubekayo senkampani esihlobene nezimangalo zokuthi imishanguzo yokubulala ukhula iRoundup idala uhlobo lomdlavuza olwaziwa njenge-non-Hodgkin lymphoma (NHL).

Lesi sivumelwano senzelwe ukunxephezela abantu abake bavezwa yimikhiqizo ye-Roundup futhi asebevele benayo i-NHL noma bangathuthukisa i-NHL ngokuzayo, kepha abangakazithathi izinyathelo zokufaka icala.

Iqembu elincane labameli abahlanganisa lolu hlelo neBayer bathi "luzosindisa izimpilo" futhi linikeze izinzuzo ezinkulu kubantu abakholelwa ukuthi baba nomdlavuza ngenxa yokuvezwa yimikhiqizo yenkampani yokubulala ukhula.

Kepha abameli abaningi abagxeka lolu hlelo bathi uma luvunywa luzobeka isibonelo esiyingozi kwezinye izinhlobo zamacala athinta inqwaba yabantu abalimele yimikhiqizo noma imikhuba yezinkampani ezinamandla.

"Lesi akusona isiqondiso esifuna uhlelo lwezobulungiswa luhambe," kusho ummeli uGerald Singleton, inkampani yakhe ejoyine nezinye izinkampani zabameli ezingaphezu kuka-60 ukuphikisana nohlelo lukaBayer. "Asikho isimo lapho lokhu kuhle kwabamangali."

Uhlelo lokukhokha lukaBayer lwafakwa eNkantolo yesiFunda sase-US esifundeni esiseNyakatho neCalifornia ngoFebhuwari 3, futhi kumele livunyelwe yiJaji Lesifunda sase-US uVince Chhabria ukuze lisebenze kahle. Uhlelo lokukhokhelwa ngaphambi kwesikhathi olwethulwe ngonyaka odlule lwalungu- edelelwa uChabria abese ehoxa. Ijaji belibheke ukwedluliswa kwamacala e-federal multidistrict Roundup okubandakanya izinkulungwane zabamangali abavela e-United States.

Izimpendulo zohlelo lokukhokha kumele zilindeleke ngoMashi 3 bese kulalelwa lolu daba kulindeleke ukuthi kube ngoMashi 31.

Okukhathaza kakhulu ukuthi abasebenzisi be-Roundup bamanje abangahle babe nomdlavuza futhi bafune ukumangalela ngokuzayo bazoba ngaphansi kwemibandela yokuxazululwa kwezigaba ngaphandle kokuthi baphume ngokusemthethweni kuleyo nkathi esikhathini esithile. Omunye wemibandela abazobe bekhonjelwe wona uzobavimba ekufuneni ukulimala kokujeziswa kunoma yiliphi icala elizayo.

Leyo migomo neminye ebekiwe ayinabulungiswa ngokuphelele kubasebenzi basemapulazini nakwabanye okulindeleke ukuthi babe nomdlavuza ngokuzayo kusukela ekuvezweni yimikhiqizo yenkampani yokubulala ukhula, ngokusho kukaSingleton. Lolu hlelo luzuzisa iBayer futhi luhlinzeka "ngemali yegazi" ezinkampanini ezine zabameli ezisebenzisane neBayer ukwakha lolu hlelo, esho.

Lawo mafemu asebenzisana neBayer ukusungula nokuphatha uhlelo bazothola isamba esihlongozwayo esingu- $ 170 million uma uhlelo luqala ukusebenza.

U-Elizabeth Cabraser, ongomunye wabameli abakha lesi sakhiwo esisha esihlongozwayo, uthe ukugxekwa akuyona incazelo efanelekile ngalesi sivumelwano. Empeleni, uthe lolu hlelo “lunikeza ukufinyelela okubalulekile futhi okudingeka ngokushesha, imfundo, ukufinyelela kwezempilo, kanye nezinzuzo zesinxephezelo” kubantu abake bathola umuthi wokubulala ukhula weMonsanto's Roundup kodwa abangakenzi i-non-Hodgkin lymphoma (NHL).

"Sifuna ukwamukelwa kwalesi sivumelwano ngoba sizosindisa izimpilo futhi sithuthukise nezinga lempilo ngokuxilonga kusenesikhathi, sisize abantu… sibazise futhi siqwashise umphakathi ngobudlelwano obuphakathi kweRoundup neNHL…" esho.

Okhulumela iBayer akaphendulanga esicelweni sokuphawula.

Indawo entsha ehlongozwayo kuhloswe ngamacala azayo futhi ahlukile ku- $ 11 billion iBayer ebekelwe ukukhokhela izimangalo zomdlavuza ezikhona zase-US. Abantu abathintwe yisiphakamiso sokukhokhelwa kwesigaba kungabantu nje kuphela abaye bavezwa ku-Roundup kepha abakabi kumacala futhi abakathathanga zinyathelo kunoma yiliphi icala.

IBayer ibinenkinga yokuthola ukuthi ingaqedwa kanjani amacala omdlavuza weRoundup selokhu ithenge iMonsanto ngo-2018. Le nkampani ilahlekelwe yizo zonke izilingo ezintathu ebezibanjiwe kuze kube manje futhi yalahlekelwa yizikhalazo zokuqala ezazifuna ukuguqula ukulahleka kwecala.

Amajaji kwesinye nesinye sezivivinyo akatholanga lokho kukaMonsanto kuphela ukhula lwe-glyphosate-based kubangela umdlavuza kepha nokuthi uMonsanto uchithe amashumi eminyaka efihla izingozi.

Yize lesi sivumelwano esihlongozwayo sithi “sibhekana nezikhalazo ezine ezaphakanyiswa iNkantolo maqondana nesinqumo sangaphambili, esasihoxisiwe,” u-Singleton nabanye abameli ababandakanyeka kweqembu eliphikisayo bathi lesi sicelo esisha sokubhadala simbi njengaleso sokuqala.

Ngaphezu kokukhathazeka ukuthi amalungu ekilasi ngeke abe nelungelo lokufuna izicelo zokukhokhelwa isijeziso, abagxeki baphikisana nesikhathi seminyaka emine "sokuma" esivimba ukufakwa kwamacala amasha. Abagxeki bathi futhi uhlelo lokwazisa abantu ngokuhlala ngezigaba alwanele. Abantu bazoba nezinsuku eziyi-150 ngemuva kwesaziso sokuthi “baphume” ekilasini. Uma bengaphumi, basekilasini ngokuzenzekelayo.

Abagxeki baphikisana nokwakhiwa okuhlongozwayo kwephaneli lesayensi elizosebenza "njengesiqondisi" sokwengezwa kwezinketho zesinxephezelo esikhathini esizayo "nokunikeza ubufakazi mayelana nokubulawa kwe-carcinogenicity - noma cha - kweBayer. Njengoba kunikezwe umlando obhaliwe kaMonsanto wokukhohlisa okutholakele kwesayensi, umsebenzi wephaneli lesayensi uzoba yinsolo, kusho uSingleton.

Isikhathi sokuqala sokukhokha sasizosebenza okungenani iminyaka emine futhi singanwetshwa ngemuva kwalesi sikhathi. Uma iBayer ikhetha ukungaqhubeki nesikhwama sesinxephezelo ngemuva kwesikhathi sokuqala sokukhokha, izokhokha enye imali eyizigidi ezingama- $ 200 njenge- “pay end” esikhwameni sesinxephezelo, kusho isifinyezo sokukhokha.

Kunikezwe “isinxephezelo esikhulu”

Amafemu abhalise isivumelwano neBayer athi ekufayeleni kwabo enkantolo ukuthi lesi sivumelwano sihlelelwe ukunikeza abamangali abangase babe khona lokho "okufeza izintshisekelo zabo," kufaka phakathi ithuba lokuthola "isinxephezelo esikhulu" uma bethuthukisa i-non-Hodgkin lymphoma .

Lolu hlelo ludinga ukusungulwa kwesikhwama sezinxephezelo ukwenza imiklomelo ephakathi kuka- $ 10,000 kuya ku- $ 200,000 ngelungu ngalinye lesigaba. "Imiklomelo Yokukhokha Esheshayo" engu- $ 5,000 izotholakala ngokushesha, okudinga nje ukukhonjiswa kokuchayeka nokuxilongwa.

Labo bantu baqale ukuvezwa kumikhiqizo ye-Roundup okungenani izinyanga eziyi-12 ngaphambi kokutholakala kwabo bazokwazi ukuthola imiklomelo. Imiklomelo engaphezulu kwama- $ 200,000 ingenziwa "ngezimo ezingavamile." Lawo malungu ekilasi afanelekayo atholakale ene-NHL ngaphambi kukaJanuwari 1, 2015, ngeke athole imiklomelo engaphezu kwe- $ 10,000, ngokwecebo. 

Isivumelwano sizohlinzeka ngezeluleko zamahhala zomthetho futhi sinikeze ”ukwesekwa ukusiza amalungu ekilasi ekuzulazuleni, ekubhaliseni nasekufakeni izicelo zemihlomulo yokuhlala.”

Ngokwengeziwe, lesi siphakamiso sithi ukukhokhelwa kuzokhokhela ucwaningo lwezokwelapha nolwezesayensi ekutholeni nasekwelapheni i-NHL.

Okuqaphelekayo, uhlelo luthi akekho umuntu ozolahlekelwa yilungelo lakhe lokufaka icala ngaphandle uma ekhetha ukwamukela isinxephezelo esikhwameni sesinxephezelo, futhi akekho noyedwa odinga ukwenza lokho kuze kube lelo lungu lesigaba ngasinye litholakala ukuthi line-NHL. Bebengeke bakwazi ukufuna umonakalo wokujeziswa kepha bebengafuna esinye isinxephezelo.

“Noma yiliphi ilungu lesigaba elingafaki isimangalo futhi lamukele isinxephezelo somuntu ngamunye ligcina ilungelo lalo lokumangalela iMonsanto ngokukhokhelwa isinxephezelo kunoma iyiphi inkolelo-mbono yezomthetho, okubandakanya ukulimala komuntu, ukukhwabanisa, ukumelwa ngendlela engeyiyo, ubudedengu, ukufihla inkohliso, ukumelwa kabi ngobudedengu, ukwephula iwaranti, ukukhangisa okungelona iqiniso , nokwephula noma ikuphi ukuvikelwa komthengi noma umthetho noma izenzo ezingalungile nezikhohlisayo, ”kusho uhlelo.

Ukuqwashisa abantu ngokuxazululwa kwesenzo sekilasi, izaziso zizothunyelwa ngeposi / zithunyelwe nge-imeyili emapulazini, amabhizinisi nezinhlangano ezingama-266,000 kanye nezinhlangano zikahulumeni lapho ukubulala ukhula kwenkampani bekungasetshenziswa kanye nabantu abangama-41,000 abangenayo iHodgkin lymphoma futhi bacelwe ukuthola imininingwane ngesifo sabo. Ngokwengeziwe izingqwembe zizothunyelwa ngeposi ezitolo ezingama-2,700 XNUMX zibacela ukuthi babhale izaziso zokuxazululwa kwezigaba zesigaba.

Njengengxenye yendawo yokuhlala ehlongozwayo, iBayer ithe izofuna imvume kwa-Environmental Protection Agency (EPA) yokwengeza imininingwane kumalebula emikhiqizo yayo esekwe ku-glyphosate efana ne-Roundup ezonikeza izixhumanisi zokufinyelela kwizifundo zesayensi kanye nolunye ulwazi mayelana ne-glyphosate ukuphepha. Kodwa abagxeki bathi ukuhlinzeka ngezixhumanisi zewebhusayithi akwanele futhi iBayer idinga ukubeka isexwayiso esiqondile sengozi yomdlavuza emikhiqizweni yokubulala ukhula.

Ukuxazululwa kwesenzo esenziwe ngezigaba kusongela ukuthinta “amakhulu ezinkulungwane noma ngisho izigidi” zabantu abaye bavezwa i-Roundup futhi "baphakamisa imibuzo 'eyingqayizivele' futhi ejulile" ngaphansi koMthethosisekelo wase-US, ngokusho kuka inkantolo yokugcwalisa ngokuphikisana nohlelo lweBayer olwenziwe ngummeli wabamangali u-Elizabeth Graham.

UGraham utshele inkantolo ukuthi uma lolu hlelo lwamukelwa lungaba "nomthelela omangazayo hhayi kuleli cala kuphela, kepha nakusasa lecala lokuhlukunyezwa kwabantu abaningi."

Abalimi abamnyama

 INational Black Farmers Association (NBFA) ilinganisele lolu daba ngoLwesithathu, yafaka ukugcwaliswa okude nenkantolo kaChhabria ethi "ingxenye enkulu" yamalungu ayo angaphezu kwe-100,000 "adalulwe futhi angalimala yiRoundup, kanye nesithako sayo esisebenzayo i-glyphosate."

Iningi labalimi selivele lisungule i-lymphoma engeyona eye-Hodgkin abasola ngokusetshenziswa kwe-Roundup, futhi "ingebhe enkulu kakhulu ukuthi bazosheshe babe nezimpawu," kusho ukugcwalisa kwe-NBFA.

I-NBFA ifuna ukubona imikhiqizo ye-Roundup isuswa kwezentengiselwano noma kwezinye izinguquko ezenziwe ukuvikela abalimi, kusho ukufayila.

Ukukhathazeka kwe-NBFA kudinga ukuthi kubhekwane nakho yinkantolo, ikakhulukazi njengoba iBayer ibheka “ukulungisa isenzo sesigaba ngeqoqo labameli abathi bamele izintshisekelo zabo bonke abalimi abadalulwe ku-Roundup kodwa abasazothuthukisa kubangela umdlavuza. ”

Amacala enkantolo e-Australia

Njengoba iBayer isebenza ukuqeda amacala eRoundup e-United States, inkampani nayo ibhekene nezimangalo ezifanayo zabalimi nabanye abase-Australia. Isenzo sekilasi esifakwe iMonsanto siyaqhubeka, kanti ummangali oholayo uJohn Fenton, owafaka isicelo seRoundup njengengxenye yomsebenzi wasepulazini. UFenton watholakala ene-non-Hodgkin lymphoma ngo-2008.

Uchungechunge lwezinsuku ezisemqoka selusunguliwe: IMonsanto inangoMashi 1 ukuhlinzeka ngemibhalo yokutholwa kwabameli babamangali kanti uJuni 4 yisikhathi esinqunyiwe sokushintshaniswa kobufakazi bochwepheshe. Amaqembu azongena ekuxazululeni ngoJulayi 30 kanti uma kungenakutholakali lutho leli cala lizoqala ukuqulwa ngecala ngoMashi 2022.

UFenton uthe yize "ezolithanda ithuba" lokuthi aquliswe icala axoxe indaba yakhe, unethemba lokuthi ukulamula kuzoxazulula lolu daba. “Ngicabanga ukuthi ukuvumelana sekuqala ukushintsha ngenxa yalokhu ebekwenzeka eMelika. Abalimi sebazi kangcono futhi ngikholwa wukuthi bathatha izinyathelo zokuqapha ezingaphezu kwezangaphambili.

UFenton uthe unethemba lokuthi iBayer ekugcineni izobeka ilebula lokuxwayisa emithini yokubulala ukhula yeMonsanto.

"Okungenani ngesexwayiso umsebenzisi angazenzela eyakhe ingqondo ngokuthi iyiphi i-PPE (imishini yokuzivikela) akhetha ukuyigqoka."

Olunye ucwaningo lwe-Roundup luthola izixhumanisi ezingaba nezinkinga zempilo yabantu

Phrinta imeyili Ungahlukıselana Ephathwayo

(Kubuyekezwe uFebhuwari 17, kungeza ukugxekwa kokufunda)

A iphepha elisha lesayensi Ukuhlola imithelela yezempilo engaba khona ye-Roundup herbicides kutholakale ukuxhumana phakathi kokuchayeka kumakhemikhali okubulala ukhula i-glyphosate nokwanda kohlobo lwe-amino acid olwaziwa njengengozi yesifo senhliziyo.

Abaphenyi benza izinqumo zabo ngemuva kokudalula amagundane akhulelwe kanye namazinyane abo asanda kuzalwa ku-glyphosate ne-Roundup ngamanzi okuphuza. Bathe babheke ngqo imiphumela ye-glyphosate-based herbicides (GBH) kuma-metabolites we-urinary nokuxhumana ne-gut microbiome ezilwaneni.

Abaphenyi bathi bathole ukwanda okukhulu kwe-amino acid ebizwa nge-homocysteine ​​emidlwane yamaduna evezwe ku-glyphosate ne-Roundup.

"Ucwaningo lwethu lunikeza ubufakazi bokuqala bokuthi ukuvezwa kwe-GBH esetshenziswa kakhulu, kumthamo wokuvezwa komuntu owamukelekayo njengamanje, uyakwazi ukuguqula imetabolites yomchamo kubo bobabili abantu abadala bamagundane namazinyane," kusho abaphenyi.

Leli phepha elinesihloko esithi “Ukuvezwa komthamo ophansi wemithi yokubulala ukhula eglyphosate kuphazamisa i-metabolism yomchamo nokusebenzisana kwayo ne-gut microbiota,” kubhalwe ngabaphenyi abahlanu abasebenzisana ne-Icahn School of Medicine eNtabeni iSinayi eNew York kanti abane baphuma eRamazzini Institute eBologna, e-Italy. Ishicilelwe kumagazini iScientific Reports ngoFebhuwari 5.

Ababhali bavumile ukulinganiselwa okuningi esifundweni sabo, kufaka phakathi usayizi omncane wesampula, kepha bathi umsebenzi wabo ukhombisile ukuthi "ukutholakala komthamo ophansi wokukhulelwa kanye nobuncane be-glyphosate noma i-Roundup kushintshe kakhulu ama-biomarker amaningi womchamo, emadamini nasenzalweni."

Lolu cwaningo lungolokuqala ngoshintsho lwe-metabolomic ye-urinary olwenziwe ngama-herbicides asuselwa ku-glyphosate emithamo njengamanje ebhekwa njengephephile kubantu, kusho abacwaningi.

Leli phepha lilandela ukushicilelwa ngenyanga edlule ka isifundo emaphephandabeni Impilo Yemvelo ethola i-glyphosate kanye nomkhiqizo we-Roundup kungashintsha ukwakheka kwe-gut microbiome ngezindlela ezingaxhunyaniswa nemiphumela emibi yezempilo. Ososayensi abavela eRamazzini Institute nabo babambe iqhaza kulolo cwaningo.

URobin Mesnage, ongomunye wababhali bephepha elashicilelwa ngenyanga edlule ku-Environmental Health Perspectives, wakuphikisa ukuba semthethweni kwephepha elisha. Uthe ukuhlaziywa kwedatha kukhombisa umehluko otholakele phakathi kwezilwane ezivezwe ku-glyphosate nalezo ezingadalulwanga - izilwane ezilawulayo - nazo bezingatholakala ngokufanayo ngemininingwane ekhiqizwe ngokungahleliwe.

“Sekukonke, ukuhlaziywa kwedatha akusekeli isiphetho sokuthi i-glyphosate iphazamisa i-metabolism yomchamo kanye ne-gut microbiota yezilwane eziveziwe,” kusho uMesnage. "Lolu cwaningo luzoqhubeka nokudida kancane impikiswano ngobuthi be-glyphosate."

Izifundo ezimbalwa zakamuva ku-glyphosate naku-Roundup bathole ukukhathazeka okuningi.

I-Bayer, eyathola ifa lomkhiqizo we-herbicide wase-Monsanto's glyphosate kanye nephothifoliyo yezimbewu ezakhiwe ngezofuzo ngesikhathi ithenga inkampani ku-2018, igcizelela ukuthi inqwaba yezifundo zesayensi emashumini eminyaka iqinisekisa ukuthi i-glyphosate ayibangeli umdlavuza. Isikhungo Sokuvikelwa Kwezemvelo e-US kanye nezinye izinhlaka eziningi ezilawula umhlaba nazo azibheki imikhiqizo ye-glyphosate njenge-carcinogenic.

Kepha i-World Health Organisation's International Agency for Research on Cancer ngonyaka ka-2015 yathi ukubuyekezwa kocwaningo lwesayensi kutholakale ubufakazi obanele bokuthi i-glyphosate iyi-carcinogen yabantu.

IBayer ilahlekelwe yizilingo ezintathu kwezintathu ezilethwe abantu abasola umdlavuza wabo ngokuvezwa yimithi yokubulala ukhula kaMonsanto, kanti iBayer ngonyaka odlule ithe izokhokha cishe amaRandi ayizigidi eziyizinkulungwane eziyi-11 ukukhokha izimangalo ezifanayo ezingaphezu kwezingu-100,000 XNUMX.

 

 

IBayer yenza uhlelo olusha lwama- $ 2 billion lokuqeda izimangalo zomdlavuza zeRoundup ezizayo

Phrinta imeyili Ungahlukıselana Ephathwayo

Umnikazi weMonsanto uBayer AG uthe ngoLwesithathu ubesazama futhi ukuphatha nokuxazulula izimangalo zomdlavuza zeRoundup ezizayo, kubekwa eceleni isivumelwano esingu- $ 2 billion neqembu labammeli bommangali uBayer athemba ukuthi bazothola ukuvunywa yijaji likahulumeni ngubani wenqaba uhlelo lwangaphambilini Ihlobo elidlule.

Ngokuphawulekile, lesi sivumelwano sidinga iBayer ukuthi ifune imvume kwa-Environmental Protection Agency (i-EPA) ukufaka imininingwane kumalebula emikhiqizo yayo esekwe ku-glyphosate efana ne-Roundup ezonikeza izixhumanisi zokufinyelela ezifundweni zesayensi kanye nolunye ulwazi mayelana nokuphepha kwe-glyphosate.

Ukwengeza, ngokusho kukaBayer, lolu hlelo ludinga ukusungulwa kwesikhwama esizonxephezela "abafaka izicelo ezifanelekile" ohlelweni lweminyaka emine; ukusungula iphaneli lesayensi elelulekayo okutholakele kwalo kungasetshenziswa njengobufakazi kumacala angahle abe khona esikhathini esizayo; kanye nokuthuthukiswa kwezinhlelo zokucwaninga nokuxilonga zocwaningo lwezokwelapha kanye / noma lwesayensi ekuhloleni nasekwelapheni i-non-Hodgkin lymphoma.

Uhlelo kumele luvunyelwe yiJaji Lesifunda sase-US uVince Chhabria weNkantolo yesiFunda sase-US esiFundeni saseNyakatho saseCalifornia. UChhabria ubengamele ukubekwa kwamacala amaningi eRoundup multidistrict.

UBayer uthe amalungu amakilasi afanelekayo eminyakeni emine ezayo azokwazi ukuthola amazinga wemiklomelo ekhokhelwayo ngokuya ngemikhombandlela ebekwe esivumelwaneni. “Isigaba sokuhlala” sibhekise kubantu ababekade bevezwa yimikhiqizo ye-Roundup kepha bengakafaki icala enkantolo abathi balimalekile ngenxa yalokho kuvezwa.

Amalungu ekilasi lezokuhlala azokwazi ukuthola isinxephezelo phakathi kuka- $ 10,000 kuya ku- $ 200,000, kusho uBayer.
Ngokwesivumelwano, ukusatshalaliswa kwesikhwama sokuhlala kuzokwenzeka kanjena:
* Isikhwama Sesinxephezelo - Okungenani ama- $ 1.325 billion
* Uhlelo Lokuhlinzeka Ngokutholakala Kokuxilonga - $ 210 million
* Uhlelo Lwezimali Zocwaningo - $ 40 million
* Izindleko Zokulawulwa Kwezokuhlala, Izindleko Zokweluleka KwePhaneli Yesayensi, Izindleko Zesigaba Sokuhlala, Izintela,
kanye nezimali nezindleko ze-Ecrow Agent - Kuze kube yizigidi ezingama- $ 55
Uhlelo lokuhlongozwa oluhlongozwayo lwamacala ezenzo zesigaba esizayo luhlukile ku- isivumelwano sokukhokha IBayer yenziwa nabameli bamangali angamashumi ezinkulungwane asebevele baletha izimangalo ezithi ukutholakala kweRoundup nabanye ababulali bokhula baseMonsanto glyphosate kubenze ukuthi bathuthukise i-non-Hodgkin lymphoma.
IBayer ibinenkinga yokuthola ukuthi ingaqedwa kanjani amacala omdlavuza weRoundup selokhu ithenge iMonsanto ngo-2018. Le nkampani ilahlekelwe yizo zonke izilingo ezintathu ebezibanjiwe kuze kube manje futhi yalahlekelwa yizikhalazo zokuqala ezazifuna ukuguqula ukulahleka kwecala.
Amajaji kwesinye nesinye sezivivinyo akatholanga lokho kukaMonsanto kuphela ukhula lwe-glyphosate-based kubangela umdlavuza kepha nokuthi uMonsanto uchithe amashumi eminyaka efihla izingozi.

Ucwaningo olusha luthola izinguquko ezihlobene ne-glyphosate ku-gut microbiome

Phrinta imeyili Ungahlukıselana Ephathwayo

Ucwaningo olusha lwezilwane olwenziwe iqembu labaphenyi baseYurophu lithole ukuthi amazinga aphansi okhula olubulala ukhula amakhemikhali glyphosate kanye nomkhiqizo osuselwa ku-glyphosate-based Roundup kungashintsha ukwakheka kwe-gut microbiome ngezindlela ezingaxhunyaniswa nemiphumela emibi yezempilo.

Leli phepha, ishicilelwe ngoLwesithathu kulo magazini Impilo Yemvelo, ibhalwe ngabaphenyi abayi-13, kubandakanya nomholi oqhuba izifundo uDkt.Michael Antoniou, oyinhloko yeGene Expression and Therapy Group eMnyangweni Wezokwelapha Nemolekyuli Yezakhi zofuzo eKing's College eLondon, noDkt. iqembu elifanayo. Ososayensi abavela eRamazzini Institute eBologna, e-Italy, babambe iqhaza ocwaningweni njengoba kwenza ososayensi baseFrance nabaseNetherlands.

Imiphumela ye-glyphosate ku-gut microbiome itholwe ukuthi ibangelwe yindlela efanayo yokusebenza lapho i-glyphosate isebenza ukubulala ukhula nezinye izitshalo, kusho abacwaningi.

Amagciwane asemathunjini omuntu afaka izinhlobo ezahlukahlukene zamagciwane kanye nesikhunta esinomthelela emisebenzini yokuzivikela ezifweni nakwezinye izinqubo ezibalulekile, nokuphazamiseka kwalolo hlelo kungaba nomthelela ezigulini zezifo, kusho abacwaningi.

"Kokubili i-glyphosate ne-Roundup kube nomthelela ekubunjweni kwenani lamagciwane," kusho u-Antoniou kusho engxoxweni. “Siyazi ukuthi amathumbu ethu ahlala ezinkulungwaneni zezinhlobo ezahlukahlukene zamagciwane kanye nokulinganisela ekwakhekeni kwawo, futhi okubaluleke kakhulu ekusebenzeni kwawo, kubalulekile empilweni yethu. Ngakho-ke noma yini ephazamisayo, ephazamisa kabi, i-gut microbiome… inamandla okudala impilo ebuthaka ngoba sisuka ekusebenzeni okulinganiselayo okulungele impilo kuya ekusebenzeni okungalingani okungaholela ezinhlotsheni eziningi zezifo ezahlukahlukene. ”

Bona ingxoxo kaCarey Gillam uDkt. Michael Antonoiu noDkt. Robin Mesnage ngocwaningo lwabo olusha olubheka umthelela we-glyphosate kwi-gut microbiome.

Ababhali bephepha elisha bathe banqume ukuthi, ngokungahambisani nokunye okushiwo ngabagxeki bokusetshenziswa kwe-glyphosate, i-glyphosate ayisebenzi njenge-antibiotic, ibulala amagciwane adingekayo emathunjini.

Esikhundleni salokho, bathola - okokuqala ngqa, bathi - ukuthi isibulala-zinambuzane siphazamise ngendlela engaba yingozi kakhulu emzileni wamakhemikhali wamakhemikhali wamathumbu amabhaktheriya ezilwane ezisetshenziswe ekuhlolweni. Lokho kuphazamiseka kwaqokonyiswa ngoshintsho ezintweni ezithile esiswini. Ukuhlaziywa kwamathumbu negazi biochemistry kuveze ubufakazi bokuthi lezi zilwane zingaphansi kwengcindezi ye-oxidative, isimo esihambisana nokulimala kwe-DNA nomdlavuza.

Abaphenyi bathi akucaci ukuthi ukuphazamiseka okuphakathi kwegciwane le-microbiome kuthinte kanjani ukucindezela komzimba.

Inkomba yengcindezi ye-oxidative yacaca kakhulu ekuhlolweni kusetshenziswa i-herbicide esekwe eglyphosate ebizwa ngeRoundup BioFlow, umkhiqizo womnikazi weMonsanto uBayer AG, kusho ososayensi.

Ababhali bokucwaninga bathi benza izifundo eziningi ukuzama ukucacisa ukuthi ngabe ingcindezi ye-oxidative abayibonayo nayo ilimaza i-DNA, ezonyusa ingozi yomdlavuza.

Ababhali bathe kudingeka ucwaningo olwengeziwe ukuqonda kahle imithelela yempilo ye-glyphosate inhibition yendlela ekhazimulayo nokunye ukuphazamiseka kwemethambo ku-gut microbiome nasegazini kepha ukutholwa kokuqala kungasetshenziswa ekwakhiweni kwama-bio-markers wezifundo ze-epidemiological kanye nokuqonda uma i-glyphosate herbicides ingaba nemiphumela yezinto eziphilayo kubantu.

Ocwaningweni, amagundane abesifazane anikezwa i-glyphosate nomkhiqizo we-Roundup. Amanani ahanjiswa ngamanzi okuphuza ahlinzekwa izilwane futhi anikezwa emazingeni amele ukungena nsuku zonke okwamukelekayo okubhekwa njengokuvikelekile ngabalawuli baseYurophu nabaseMelika.

U-Antoniou uthe imiphumela yocwaningo yakhela kolunye ucwaningo olwenza kucace ukuthi izilawuli zithembele ezindleleni eseziphelelwe yisikhathi lapho kunqunywa ukuthi yimaphi amazinga “aphephile” e-glyphosate namanye ama-pesticides ekudleni nasemanzini. Izinsalela zemithi yokubulala izinambuzane ezisetshenziswa kwezolimo zivame ukutholakala ebangeni lokudla okusetshenziswa njalo.

"Abalawuli kumele bangene ekhulwini lama-XNUMX leminyaka, bayeke ukuhudula izinyawo zabo… bamukele izinhlobo zokuhlaziya esikwenzile kulolu cwaningo," kusho u-Antoniou. Uthe ukwenziwa kwamangqamuzana, okuyingxenye yegatsha lesayensi eyaziwa ngokuthi “OMICS,” kuguqula isisekelo solwazi mayelana nemithelela ukuchayeka kwamakhemikhali okunayo empilweni.

Isifundo segundane kodwa esakamuva ochungechungeni lwezivivinyo zesayensi ezihlose ukunquma ukuthi ngabe i-glyphosate ne-glyphosate-based herbicides - kufaka phakathi i-Roundup - ingaba yingozi kubantu, ngisho nasemazingeni abalawuli be-exposure bathi baphephile.

Izifundo eziningi ezinjalo zithole ukukhathazeka okuningi, kufaka phakathi eyodwa eyanyatheliswa ngoNovemba  ngabaphenyi abavela eNyuvesi yaseTurku eFinland abathi bakwazile ukuthola, "ngokulinganisela okulindelekile," ukuthi cishe amaphesenti angama-54 ezinhlobo ezisengxenyeni ye-gut microbiome yomuntu "angazwela" ku-glyphosate.

Njengoba abacwaningi banda bheka ukuqonda i-microbiome yomuntu neqhaza eliyidlalayo empilweni yethu, imibuzo mayelana nemithelela engaba khona ye-glyphosate kwi-gut microbiome bekungeyona nje impikiswano emibuthanweni yesayensi, kodwa futhi nasezinkantolo.

Ngonyaka odlule, iBayer bavuma ukukhokha u- $ 39.5 million ukuxazulula izimangalo zokuthi iMonsanto inezikhangiso ezidukisayo eziqinisekisa ukuthi i-glyphosate yenze kuphela i-enzyme ezitshalweni futhi ayinakuba nomthelela ofanayo ezifuyweni nakubantu. Abamangali kuleli cala kuthiwa i-glyphosate babhekise enzyme etholakala kubantu nasezilwaneni eziqinisa amasosha omzimba, ukugaya nokusebenza kwengqondo.

I-Bayer, eyathola ifa lomkhiqizo we-herbicide wase-Monsanto's glyphosate kanye nephothifoliyo yezimbewu ezakhiwe ngezofuzo ngesikhathi ithenga inkampani ku-2018, igcizelela ukuthi inqwaba yezifundo zesayensi emashumini eminyaka iqinisekisa ukuthi i-glyphosate ayibangeli umdlavuza. Isikhungo Sokuvikelwa Kwezemvelo e-US kanye nezinye izinhlaka eziningi ezilawula umhlaba nazo azibheki imikhiqizo ye-glyphosate njenge-carcinogenic.

Kepha i-World Health Organisation's International Agency for Research on Cancer ngonyaka ka-2015 yathi ukubuyekezwa kocwaningo lwesayensi kutholakale ubufakazi obanele bokuthi i-glyphosate iyi-carcinogen yabantu.

Kusukela ngaleso sikhathi, iBayer ilahlekelwe yizilingo ezintathu kwezintathu ezilethwe ngabantu abasola umdlavuza wabo ngokuvezwa yimithi yokubulala ukhula kaMonsanto, kanti iBayer ngonyaka odlule ithe izokhokha cishe ama- $ 11 billion ukukhokhela izimangalo ezifanayo ezingaphezu kwezingu-100,000.

Ukufa nokuhlala njengoba iBayer iqhubeka nokuzama ukuqeda amacala we-Roundup

Phrinta imeyili Ungahlukıselana Ephathwayo

Ezinyangeni eziyisikhombisa ngemuva kweBayer AG umemezele izinhlelo ngokuxazululwa kokushonelwa kwamacala omdlavuza we-US Roundup, umnikazi waseJalimane weMonsanto Co uyaqhubeka nokusebenza ukuxazulula amashumi ezinkulungwane zezimangalo ezilethwe abantu abaphethwe umdlavuza abathi zibangelwe yimikhiqizo yokubulala ukhula kaMonsanto. NgoLwesithathu, elinye icala livele lathola ukuvalwa, yize ummangali angiphilelanga ukukubona.

Abameli bakaJaime Alvarez Calderon, bavumelane ekuqaleni kwaleli sonto ngesinqumo esanikezwa yiBayer ngemuva kweJaji Lesifunda saseMelika uVince Chhabria ngoMsombuluko inqatshelwe isahlulelo esifingqiwe ngokuthanda iMonsanto, ukuvumela icala ukuthi lisondele ecaleni.

Isivumelwano sizoya emadodaneni amane ka-Alvarez ngoba ubaba wabo oneminyaka engu-65, osebenza isikhathi eside esebenzela iwayini eNapa County, California, ushone nje esikhathini esingaphezu konyaka esedlule kusuka kwi-non-Hodgkin lymphoma usola umsebenzi wakhe wokufafaza i-Roundup ezungeze impahla ye-winery iminyaka.

Ekulalelweni kwenkantolo ngoLwesithathu, ummeli womndeni wakwa-Alvarez uDavid Diamond utshele iJaji uChhabria ukuthi lesi sinqumo sizolivala leli cala.

Ngemuva kokuqulwa kwecala, uDiamond wathi u-Alvarez usebenze e-winery iminyaka engama-33, esebenzisa isifutho sasebhakeni ukufaka isicelo sikaMonsanto kusekelwe ku-glyphosate ukubulala ukhula kuma-acreage asakazekayo eqembu le-Sutter Home lamawayini. Wayevame ukuya ekhaya kusihlwa nezingubo ezimanzi ngomuthi wokubulala ukhula ngenxa yokuvuza kwemishini kanye nombulali wokhula okhukhuleka emoyeni. Watholwa ngo-2014 ene-non-Hodgkin lymphoma, elashwa kaningi ngamakhemikhali nezinye izindlela zokwelashwa ngaphambi kokushona ngoDisemba 2019.

UDiamond uthe ujabule ngokuxazulula leli cala kodwa unamacala angama-Roundup "angu-400 plus" amanye angakalungiswa.

Akayedwa. Okungenani uhhafu weshumi namanye amafemu wezomthetho wase-US anabamangali baseRoundup abafuna izilungiselelo zesilingo zango-2021 nangaphezulu.

Kusukela ukuthenga iMonsanto ku-2018, iBayer ibilokhu ilwela ukuthola ukuthi ungayenza kanjani kuqedwe ukuqulwa kwamacala lokho kufaka abamangali abangaphezu kuka-100,000 XNUMX e-United States. Le nkampani ilahlekelwe yizo zonke izivivinyo ezintathu ebezibanjelwe kuze kube yimanje futhi ilahlekelwe yizikhalazo zokuqala ezifuna ukuguqula ukulahleka kwecala. Amajaji kwesinye nesinye sezivivinyo athola leyo kaMonsanto ukhula lwe-glyphosate-based kubangela umdlavuza nokuthi uMonsanto uchithe amashumi eminyaka efihla izingozi.

Ngaphezu kwemizamo yokuxazulula izimangalo ezisalindile njengamanje, iBayer inethemba lokuthi izokwakha indlela yokuxazulula izimangalo ezingaba khona ezingabhekana nazo kubasebenzisi beRoundup abathuthukisa i-non-Hodgkin lymphoma ngokuzayo. Uhlelo lwayo lokuqala lokusingatha amacala esikhathi esizayo yenqatshwa nguJaji Chhabria futhi inkampani ayikamemezeli uhlelo olusha.

Isimemo sikaBayer sokuxazulula izimangalo zomdlavuza wase-US Roundup ziyaqhubeka

Phrinta imeyili Ungahlukıselana Ephathwayo

Umnikazi weMonsanto uBayer AG wenza inqubekela phambili ekuxazululeni izinkulungwane zamacala aseMelika alethwe ngabantu abathi bona noma abathandekayo babo baba nomdlavuza ngemuva kokuchayeka emithini yokubulala ukhula iMonsanto's Roundup.

Izincwadi zakamuva ezivela kubameli babamangali eziya kumakhasimende abo zigcizelele leyo nqubekelaphambili, eqinisekisa ukuthi iningi labamangali likhetha ukubamba iqhaza kulesi sikhokhelo, yize kunezikhalazo zabamangali abaningi zokuthi babhekene neziphakamiso zokukhokha ezincane ezingafanele.

Kwezinye izibalo, ukukhokhiswa okujwayelekile kuzoshiya isinxephezelo esincane, mhlawumbe izinkulungwane ezimbalwa zamaRandi, kubamangali ngabanye ngemuva kokukhokhwa kwemali yabameli kanye nezindleko ezithile zezokwelapha ezibuyiswayo.

Yize kunjalo, ngokwencwadi ethunyelwe kwabamangali ngasekupheleni kukaNovemba ngenye yamafemu abameli abahamba phambili enkantolo, ngaphezu kwamaphesenti angama-95 "wabamangali abafanelekile" banquma ukubamba iqhaza ohlelweni lokuxazulula okuxoxiswene ngalo nenkampani neBayer. “Umphathi wezindawo zokuhlala” manje unezinsuku ezingama-30 zokubuyekeza amacala bese eqinisekisa ukufaneleka kwabamangali ukuthola izimali zokuhlala, ngokusho kwezincwadi.

Abantu bangakhetha ukuphuma kuleso sivumelwano bese befaka izicelo zabo ekulamuleni, kulandelwe ukulamula okuyisibopho uma befisa noma bezama ukuthola ummeli omusha ozoqula icala labo. Labo bamangali bangaba nesikhathi esinzima sokuthola ummeli ozobasiza bathathe udaba lwabo baluse enkantolo ngoba amafemu abameli avumelana nokuxazululwa kweBayer avumile ukuthi angazami amanye amacala noma asize ekulingweni okuzayo.

Omunye ummangali, ocele ukungadalulwa ngegama ngenxa yobumfihlo bezinqubo zokukhokha, uthe uyaphuma kuleso sinqumo ngethemba lokuthola imali ethe xaxa ngokulamula noma ngecala elizayo. Uthe udinga ukuhlolwa okuqhubekayo nokwelashwa komdlavuza wakhe kanti nohlaka oluhlongozwayo lokuhlalisa abantu ngeke lumshiye ngalutho ukukhokhela lezo zindleko eziqhubekayo.

"IBayer ifuna ukukhululwa ngokukhokha imali encane ngangokunokwenzeka ngaphandle kokuya ecaleni," esho.

Ukulinganiselwa okulinganiselwe kokukhokhwa okujwayelekile kwemali ngayinye kummangali kungama- $ 165,000, abameli nabamangali abathintekayo ezingxoxweni bathe. Kepha abanye abamangali bangathola okuningi kakhulu, kanti abanye bathola okungaphansi, kuya ngemininingwane yecala labo. Kunemigomo eminingi yokunquma ukuthi ngubani ongabamba iqhaza ekukhokhelweni nokuthi ingakanani imali lowo muntu angayithola.

Ukuze afaneleke, umsebenzisi we-Roundup kufanele abe yisakhamuzi sase-US, kutholakale ukuthi une-non-Hodgkin lymphoma (NHL), futhi wadalulwa ku-Roundup okungenani unyaka owodwa ngaphambi kokutholakala ukuthi une-NHL.

Isivumelwano sokukhokha neBayer sizophela lapho umphathi eqinisekisa ukuthi ngaphezu kwamaphesenti angama-93 abafaka izicelo abafanelekile, ngokwemigomo yesivumelwano.

Uma umphathi wezokukhokha ethola ummangali engafanelekile, lowo mmangali unezinsuku ezingama-30 zokudlulisa isinqumo.

Kwabamangali ababhekwa njengabafanelekile umphathi wezindawo zokuhlala uzonikeza icala ngalinye amaphuzu amaningi ngokuya ngemibandela ethile. Inani lemali ummangali ngamunye azolithola lisuselwa kunani lamaphoyinti abalwe ngesimo sawo ngasinye.

Amaphuzu esisekelo asungulwa kusetshenziswa iminyaka yomuntu lowo ngesikhathi etholakala ukuthi une-NHL kanye nezinga lobunzima "bokulimala" njengoba kunqunywa izinga lokwelashwa nomphumela. Amazinga agijima u-1-5. Umuntu oshone nge-NHL unikezwa amaphuzu esisekelo ezingeni lesi-5, ngokwesibonelo. Amaphuzu amaningi anikezwa abantu abasha abahlushwa imijikelezo eminingi yokwelashwa kanye / noma abashona.

Ngaphezu kwamaphoyinti esisekelo, ukulungiswa kuvunyelwe okunikeza amaphuzu amaningi kubamangali ababenokuchayeka okuningi ku-Roundup. Kukhona nezibonelelo zamaphoyinti amaningi ezinhlobo ezithile ze-NHL. Abamangali abatholakale benohlobo lwe-NHL olubizwa nge-Primary Central Nervous System (CNS) lymphoma bathola ukukhushulwa ngamaphesenti ayi-10 kumanani abo, isibonelo.

Abantu futhi bangadonswa amaphuzu ngokususelwa ezicini ezithile. Nazi izibonelo ezithile ezithile ezivela kumatrix wamaphoyinti asungulwe ngecala le-Roundup:

  • Uma umsebenzisi womkhiqizo we-Roundup ashone ngaphambi kukaJanuwari 1, 2009, amaphuzu aphelele wesimangalo alethwe egameni lawo azokwehliswa ngamaphesenti angama-50.
  • Uma ummangali oshonile ebengenaye umlingani noma izingane ezincane ngesikhathi sokushona kwabo kudonswa amaphesenti angama-20.
  • Uma ummangali enomdlavuza wegazi ngaphambi kokusebenzisa i-Roundup amaphuzu abo anqunywa ngamaphesenti angama-30.
  • Uma isikhathi phakathi kokuchayeka kwe-Roundup kommangali nokutholakala kwe-NHL bekungaphansi kweminyaka emibili amaphuzu asikwa ngamaphesenti angama-20.

Izimali zokuhlala kufanele ziqale ukugelezela kubahlanganyeli entwasahlobo ngezinkokhelo zokugcina ezinethemba lokuthi zenziwe ehlobo, ngokusho kwabameli abathintekayo.

Abamangali nabo bangafaka izicelo zokuba yingxenye yesikhwama semali sokulimala esingajwayelekile, esakhelwe iqembu elincane labamangali abahlushwa ukulimala okukhulu okuhlobene neNHL. Isimangalo singafanelekela isikhwama sokulimala esingajwayelekile uma ukufa komuntu ku-NHL kwenzeka ngemuva kwezifundo ezintathu noma ngaphezulu ezigcwele ze-chemotherapy nezinye izindlela zokwelapha ezinolaka.

Kusukela ethenge iMonsanto e2018, iBayer ibisokola ukuthola ukuthi izophela kanjani enkantolo ebandakanya abamangali abangaphezu kuka-100,000 e-United States. Le nkampani ilahlekelwe yizo zonke izivivinyo ezintathu ebezibanjelwe kuze kube manje futhi ilahlekelwe yizikhalazo zokuqala ezifuna ukuguqula ukulahleka kwecala. Amajaji kwesinye nesinye sezivivinyo athola leyo kaMonsanto ukhula lwe-glyphosate-based, njengeRoundup, idala umdlavuza nokuthi uMonsanto uchithe amashumi eminyaka efihla izingozi.

Imiklomelo yamajaji ifinyelele ngaphezu kwezigidi eziyizinkulungwane ezingama- $ 2, yize izahlulelo ziyalelwe ukuthi zincishiswe ngamajaji asenkantolo yokuqulwa kwamacala.

Imizamo yenkampani yokuxazulula leli cala iye yabekelwa eceleni yingqinamba yokuthi zingasuswa kanjani izimangalo ezingalethwa ngokuzayo ngabantu ababa nomdlavuza ngemuva kokusebenzisa imishanguzo yokubulala ukhula yenkampani.

Ukudluliswa Kwezilingo Kuyaqhubeka

Noma iBayer ihlose ukuqeda ukuvivinywa okuzayo ngamadola okukhokha, inkampani iyaqhubeka nokuzama ukuguqula imiphumela yezilingo ezintathu inkampani elahlekile.

Ekulahlekelweni kokuqala kwesivivinyo - Icala likaJohnson v. Monsanto - IBayer ilahlekelwe yimizamo yokuguqula amajaji athola ukuthi uMonsanto ubhekene nesifo somdlavuza kaJohnson ezingeni lenkantolo yokudlulisa amacala, kwathi ngo-Okthoba, iNkantolo Ephakeme yaseCalifornia unqabile ukubuyekeza icala.

IBayer manje inezinsuku eziyi-150 kusukela kuleso sinqumo sokucela ukuthi lolu daba luthathwe yiNkantolo Ephakeme yase-US. Le nkampani ayikasithathi isinqumo sokugcina mayelana nalesi sinyathelo, ngokusho komkhulumeli weBayer, kodwa iveze phambilini ukuthi ihlose ukuthatha lesi sinyathelo.

Uma iBayer ifaka isicelo eNkantolo Ephakeme yase-US, abameli bakaJohnson kulindeleke ukuthi bafake isicelo sokuphikisa esinemibandela becela inkantolo ukuthi ihlolisise izinyathelo zokwahlulela ezanciphisa umklomelo wamajaji kaJohnson kusuka ku- $ 289 million kuya ku- $ 20.5 million.

Amanye amacala enkantolo yaseBayer / Monsanto

Ngaphezu kwesikweletu uBayer abhekene nesibopho sakwaMonsanto sikaRoundup somdlavuza, inkampani ilwa nezikweletu zeMonsanto ezinkantolo zokungcola kwePCB nasenkingeni yokulimala kwezitshalo okubangelwe uhlelo lwezitshalo olususelwa ku-Micanto dicamba herbicide.

Ijaji lombuso eLos Angeles ngesonto eledlule wasenqaba isiphakamiso yiBayer ukukhokha imali eyizigidi ezingama- $ 648 ukuxazulula amacala asezingeni elilethwe ngabamangali abasola ukungcoliswa okuvela kuma-biphenyls anezinwele, noma ama-PCB, enziwe iMonsanto.

Nangesonto eledlule, ijaji eliqulile icala le I-Bader Farms, Inc. v. Monsanto wenqaba iziphakamiso zikaBayer zokuqulwa kwecala elisha. Ijaji lisike umonakalo wokujeziswa onikezwe yijaji, noma kunjalo, kusuka ku- $ 250 million kuya ku- $ 60 million, kushiya umonakalo ongaphelele we $ 15 million, ngomklomelo ophelele ka- $ 75 million.

Amadokhumenti atholiwe ngokutholwa kwecala likaBader kuveze ukuthi iMonsanto ne-giant BASF yamakhemikhali babazi iminyaka ukuthi izinhlelo zabo zokwethula uhlelo lwembewu yezolimo kanye namakhemikhali olususelwa ku-dicamba kungenzeka ziholele emonakalweni emapulazini amaningi ase-US.

Amaphepha amasha e-glyphosate akhomba "ekuphuthumeni" kocwaningo olwengeziwe ngomthelela wamakhemikhali empilweni yomuntu

Phrinta imeyili Ungahlukıselana Ephathwayo

Amaphepha esayensi amasha asanda kushicilelwa akhombisa ubuningi bokutholakala kokhula olubulala ukhula i-glyphosate kanye nesidingo sokuqonda kangcono umthelela ovezwa umuthi wokubulala izinambuzane odumile ongahle ube nawo empilweni yomuntu, kubandakanya nempilo yegciwane le-microbiome.

In elinye lamaphepha amasha, Abaphenyi abavela eNyuvesi yaseTurku eFinland bathi bakwazile ukuthola, "ngokulinganisela okulindelekile," ukuthi cishe amaphesenti angama-54 ezinhlobo ezisengxenyeni ye-gut microbiome yomuntu "angazwela" ku-glyphosate. Abaphenyi bathi basebenzise indlela entsha ye-bioinformatics ukwenza okutholakele.

Nge "ingxenye enkulu" yamagciwane asesiswini i-microbiome esengozini ye-glyphosate, ukutholwa kwe-glyphosate "kungathinta kakhulu ukwakheka kwe-gut microbiome yomuntu," kusho ababhali ephepheni labo, elishicilelwe kule nyanga Ijenali Yezinto Eziyingozi.

Amagciwane asemathunjini omuntu afaka izinhlobo ezahlukahlukene zamagciwane kanye nesikhunta futhi kukholelwa ukuthi kunomthelela ekusebenzeni komzimba kanye nezinye izinqubo ezibalulekile. Ama-microbiomes emathunjini angenampilo akholelwa ososayensi abathile ukuthi banikela ezinhlotsheni zezifo.

"Yize imininingwane yezinsalela ze-glyphosate ezinhlelweni zomgudu womuntu isashoda, imiphumela yethu iphakamisa ukuthi izinsalela ze-glyphosate zinciphisa ukwehluka kwamagciwane futhi zilinganise ukwakheka kwezinhlobo zamagciwane emathunjini," kusho ababhali. "Singacabanga ukuthi ukutholakala isikhathi eside ezinsaleleni ze-glyphosate kuholela ekubuseni kwamagciwane amelana nomphakathi wamagciwane."

Ukukhathazeka ngomthelela we-glyphosate kumgudu womuntu we-microbiome kusuka eqinisweni lokuthi i-glyphosate isebenza ngokukhomba i-enzyme eyaziwa njenge-5-enolpyruvylshikimate-3-phosphate synthase (EPSPS.) Le enzyme ibalulekile ekwakhiweni kwama-amino acid abalulekile.

“Ukuthola umthelela wangempela we-glyphosate ku-gut gut microbiota nakwezinye izinto eziphilayo, kudingeka izifundo ezengeziwe zokuveza izinsalela ze-glyphosate ekudleni, ukuthola imiphumela ye-glyphosate emsulwa nokwakhiwa kwezentengiselwano kuma-microbiomes nokuhlola ukuthi i-EPSPS yethu ingakanani izimpawu ze-amino acid zibikezela ukuthi amagciwane angabanjwa yi-glyphosate in vitro kanye nezimo zomhlaba wangempela, ”kuphetha ababhali bephepha elisha.

Ngaphezu kwabaphenyi abayisithupha abavela eFinland, omunye wababhali bephepha ubambisene nomnyango we-biochemistry kanye ne-biotechnology eRovira i Virgili University, eTarragona, eCatalonia, eSpain.

“Imiphumela yezempilo yomuntu ayinqunywa esifundweni sethu. Kodwa-ke, ngokuya ngocwaningo lwangaphambilini… siyazi ukuthi ushintsho ku-gut gut microbiome lungaxhunyaniswa nezifo eziningi, ”kusho umcwaningi wase-University of Turku uPere Puigbo enkulumweni abe nayo.

"Ngiyethemba ukuthi ucwaningo lwethu luvula umnyango wokuqhubeka nokuhlola, ku-in-vitro nasensimini, kanye nezifundo ezenzelwe inani labantu ukuze kukalwe umphumela ukusetshenziswa kwe-glyphosate okunayo kubantu nakwezinye izinto eziphilayo," kusho uPuigbo.

Kwethulwe ku-1974

I-Glyphosate isithako esisebenzayo kuma-Roundup herbicides kanye namakhulu eminye imikhiqizo yokubulala ukhula edayiswa emhlabeni jikelele. Yethulwa njengombulali wokhula nguMonsanto ngonyaka we-1974 futhi yakhula yaba umuthi wokubulala ukhula osetshenziswa kakhulu ngemuva kokwethulwa kukaMonsanto ngeminyaka yama-1990s yezitshalo ezakhiwe ngezakhi zofuzo ukubekezelela ikhemikhali. Izinsalela ze-glyphosate zivame ukutholakala ekudleni nasemanzini. Ngenxa yalokho, izinsalela zivame ukutholakala emchameni wabantu abavezwe ku-glyphosate ngokudla kanye / noma ngokufaka isicelo.

Abalawuli baseMelika kanye nomnikazi weMonsanto uBayer AG bagcina ukuthi akukho ukukhathazeka kwezempilo yabantu ngokuvezwa kwe-glyphosate lapho imikhiqizo isetshenziswa njengoba kuhlosiwe, kufaka phakathi okusele ekudleni.

Umzimba wocwaningo ophikisana nalezo zimangalo uyakhula, noma kunjalo. Ucwaningo ngemithelela engaba khona ye-glyphosate ku-gut microbiome alucishe luqine njengezincwadi ezihlanganisa i-glyphosate nomdlavuza, kepha luyindawo ososayensi abaningi bayaphenya.

Ngokuhlobene kancane iphepha eshicilelwe kule nyanga, iqembu labaphenyi baseWashington State University naseDuke University bathi bathole ukuxhumana phakathi kwamazinga amabhaktheriya nesikhunta emapheshana emathunjini ezingane namakhemikhali atholakala emakhaya abo. Abaphenyi abazange babheke i-glyphosate ngokuqondile, kodwa babenjalo wethukile ukuthola ukuthi izingane ezinamazinga aphezulu amakhemikhali avamile asendlini egazini lazo zibonise ukwehla kwenani nokwehluka kwamagciwane abalulekile emathunjini awo.

IGlyphosate emchameni

An iphepha elengeziwe lesayensi kushicilelwe kule nyanga kugcizelele isidingo sedatha engcono nengaphezulu uma kukhulunywa ngokuvezwa kwe-glyphosate nezingane.

Leli phepha, lishicilelwe ephephabhukwini Health Environmental ngabaphenyi abavela ku-Institute for Translational Epidemiology e-Icahn School of Medicine eNtabeni iSinayi eNew York, kungumphumela wokubuyekezwa kwezincwadi zezifundo eziningi ezibika amanani wangempela we-glyphosate kubantu.

Ababhali bathi bahlaziye izifundo ezinhlanu ezishicilelwe eminyakeni emibili edlule zibika amazinga e-glyphosate alinganiswa kubantu, kufaka phakathi ucwaningo olulodwa lapho kukalwa khona amazinga e-urinary glyphosate ezinganeni ezihlala emaphandleni aseMexico. Ezinganeni ezingama-192 ezihlala endaweni yase-Agua Caliente, amaphesenti angama-72.91 ayenezinga le-glyphosate elitholakalayo emchameni wazo, futhi zonke izingane ezingama-89 ezihlala e-Ahuacapán, eMexico, zazinamazinga atholakalayo we-pesticide emchameni wazo.

Noma ufaka izifundo ezingeziwe, kukonke, kunemininingwane embalwa mayelana namazinga e-glyphosate kubantu. Izifundo emhlabeni jikelele zingabantu abangu-4,299 kuphela, kubandakanya nezingane ezingama-520, kusho abacwaningi.

Ababhali baphethe ngokuthi okwamanje akunakwenzeka ukuqonda "ubudlelwano obungahle bube khona" phakathi kokuvezwa kwe-glyphosate nezifo, ikakhulukazi ezinganeni, ngoba ukuqoqwa kwedatha emazingeni okuvezwa kwabantu kunqunyelwe futhi akujwayelekile.

Baphawule ukuthi yize bekushoda imininingwane eqinile mayelana nemithelela ye-glyphosate ezinganeni, inani lezinsalela ze-glyphosate ezivunyelwe ngokusemthethweni ngabalawuli be-US ekudleni lenyuke kakhulu kule minyaka edlule.

"Kunezikhala ezincwadini ezibhalwe nge-glyphosate, futhi lezi zikhala kufanele zigcwaliswe ngokuphuthuma okuthile, uma kubhekwa ukusetshenziswa okukhulu kwalo mkhiqizo nokuba khona kwawo yonke indawo," kusho umbhali u-Emanuela Taioli.

Izingane zisengcupheni yokuthola izidalwa ezibulala imvelo futhi ukulandelela ukutholakala kwemikhiqizo efana ne-glyphosate ezinganeni “kuyinto ebaluleke kakhulu kwezempilo yomphakathi,” ngokusho kwabalobi bephepha.

"Njenganoma iyiphi ikhemikhali, kunezinyathelo eziningi ezibandakanyekile ekuhloleni ubungozi, okubandakanya ukuqoqa imininingwane mayelana nokuvezwa kwabantu, ukuze amazinga aletha ukulimala kubantu noma ezilwaneni ezilwaneni angaqhathaniswa namazinga okuvezwa ajwayelekile," kubhala ababhali.

“Kodwa-ke phambilini sikhombisile ukuthi imininingwane ngokuvezwa kwabantu kubasebenzi nakubantu jikelele incane kakhulu. Kunezinye izikhala zolwazi ezikhona kulo mkhiqizo, ngokwesibonelo imiphumela ku-genotoxicity yayo kubantu inqunyelwe. Impikiswano eqhubekayo mayelana nemiphumela yokuchayeka kwe-glyphosate yenza ukuthi amazinga okuchayeka emphakathini jikelele kube yinkinga ecindezelayo yezempilo yomphakathi, ikakhulukazi kulabo abasengozini enkulu.

Ababhali bathe ukuqapha amazinga we-urinary glyphosate kufanele kwenziwe kubantu abaningi.

“Siyaqhubeka nokuphakamisa ukuthi ukufakwa kwe-glyphosate njengokuvezwa okulinganisiwe ezifundweni ezimele izwe lonke njengeNational Health and Nutrition Examination Survey kuzovumela ukuqonda kangcono izingozi ezingase zibangelwe yi-glyphosate futhi kuvumele ukuqashwa okungcono kwalabo okungenzeka badalulwe futhi labo abasengozini yokuchayeka kalula, ”babhala.

I-Aspartame: Iminyaka eyishumi yeSayensi ikhomba ezingozini ezinkulu zezeMpilo

Phrinta imeyili Ungahlukıselana Ephathwayo

Umlando Omude Wokukhathazeka
Izifundo Eziyinhloko Zesayensi ku-Aspartame
Imizamo ye-PR PR
Izinkomba Zesayensi

Imininingwane ebalulekile Ngokwe-Diet Soda Chemical 

Yini i-Aspartame?

  • I-Aspartame yi-sweetener esetshenziswa kakhulu emhlabeni. Iphinde idayiswe njengeNutraSweet, Equal, Sugar Twin ne-AminoSweet.
  • I-Aspartame ikhona kokungaphezulu kwe- 6,000 imikhiqizo, kufaka phakathi iDiet Coke neDiet Pepsi, iKool Aid, iCrystal Light, iTango nezinye iziphuzo ezenziwe ngoshukela; Imikhiqizo ye-Jell-O engenashukela; I-Trident, i-Dentyne kanye neminye imikhiqizo eminingi yezinsini ezingenashukela; Amaswidi aqinile angenashukela; iziphuzo ezinoshukela ophansi noma ongenashukela njengama-ketchups nokugqoka; imithi yezingane, amavithamini kanye namaconsi okukhwehlela.
  • I-Aspartame yikhemikhali lokwenziwa elenziwe ngama-amino acid phenylalanine ne-aspartic acid, ene-methyl ester. Lapho idliwe, i-methyl ester yehla ibe yi-methanol, engaguqulwa ibe yi-formaldehyde.

Iminyaka eyishumi yezifundo iphakamisa ukukhathazeka nge-Aspartame

Njengoba i-aspartame yaqala ukwamukelwa ngo-1974, bobabili ososayensi be-FDA kanye nososayensi abazimele baphakamise ukukhathazeka ngemiphumela yezempilo engaba khona kanye nokushiyeka kusayensi ethunyelwe ku-FDA ngumenzi, uGD Searle. (IMonsanto ithenge iSearle ngo-1984).

Ngo-1987, i-UPI yashicilela uchungechunge lwama-athikili okuphenya nguGregory Gordon ebika ngalezi zinto ezikhathazayo, kufaka phakathi izifundo zakuqala ezixhumanisa i-aspartame nezinkinga zempilo, izinga elibi locwaningo oluxhaswe imboni olwaholela ekuvunyelweni kwalo, kanye nobudlelwano bomnyango obuzungezayo phakathi kwezikhulu ze-FDA kanye nemboni yokudla. Uchungechunge lukaGordon luyisisetshenziswa esibaluleke kakhulu kunoma ngubani ofuna ukuqonda umlando we-aspartame / NutraSweet:

Amaphutha ekuhlolweni kwe-European Food Safety Authority

NgoJulayi 2019 iphepha ku-Archives of Health Public, Abaphenyi baseYunivesithi yaseSussex banikeze ukuhlaziywa okuningiliziwe kokuhlolwa kokuphepha kwe-aspartame kwe-EFSA ngonyaka ka-2013 bathola ukuthi iphaneli linciphise njengokungathembeki esifundweni ngasinye kwezingu-73 ezikhombisa ukulimala, futhi lasebenzisa izindlela zokuxegisa kakhulu ukwamukela ukuthembeka okungu-84% wezifundo lokho akubutholanga ubufakazi bokulimala. "Uma kubhekwa ukushiyeka kokuhlolwa kobungozi be-aspartame kwe-EFSA, kanye nokushiyeka kwakho konke ukuhlolwa kwangaphambilini okuyingozi okusemthethweni kwe-aspartame, kungaphambi kwesikhathi ukuphetha ngokuthi kuphephile ngokwamukelekayo," kuphetha ucwaningo.

Bona Impendulo ye-EFSA nokulandelwa ngabaphenyi u-Erik Paul Millstone no-Elizabeth Dawson ku-Archives of Public Health, Kungani i-EFSA yehlise i-ADI yayo ye-aspartame noma yancoma ukuthi ukusetshenziswa kwayo kungabe kusavunyelwa? Ukusabalala kwezindaba:

  • Ochwepheshe bathi “isiphuzo sopopayi esithandwa kakhulu emhlabeni kufanele sinqatshelwe. Ochwepheshe ababili bezokuphepha kokudla bacele ukuthi iswidi yokufakelwa esetshenziswa kabanzi, i-aspartame, ivinjelwe e-UK futhi babuze ukuthi kungani kubonakale kwamukelekile kwasekuqaleni, ” I-New Food Magazine (11.11.2020) 
  • "'Ukuthengiswa kwe-aspartame kufanele kumiswe': I-EFSA esolwa ngokwenzelela ekuhloleni ukuphepha," nguKaty Askew, I-Navigator Yezokudla (7.27.2019)

Imiphumela Yezempilo Nezifundo Eziyinhloko ku-Aspartame 

Ngenkathi izifundo eziningi, ezinye zazo zixhasiwe, azibikanga zinkinga nge-aspartame, inqwaba yezifundo ezizimele ezenziwa amashumi eminyaka zixhumanise i-aspartame nohlu olude lwezinkinga zempilo, kufaka phakathi:

Cancer

Ocwaningweni olunzulu lomdlavuza kuze kube yimanje nge-aspartame, izifundo ezintathu zokuphila ezenziwa yiCesare Maltoni Cancer Research Center yeRamazzini Institute, zinikeza ubufakazi obungaguquguquki bokuba nomdlavuza kumagundane adalulwe kulokho.

  • I-Aspartame “ingumenzeli we-carcinogenic onamandla amaningi, noma ngabe isilinganiso sansuku zonke se-… singaphansi kakhulu kokudla kwansuku zonke okwamukelekayo,” ngokusho kocwaningo lwamagundane lwempilo ka-2006 Impilo Yemvelo.1
  • Ucwaningo olulandelwayo ngo-2007 luthole ukwanda okuphathelene nomthamo okuphawulekayo kumaqhubu amabi kwamanye amagundane. "Imiphumela ... iqinisekisa futhi iqinisa ukubonakaliswa kokuqala kokuhlolwa kwe- [aspartame's] okungajwayelekile kwe-carcinogenic ezingeni lomthamo eliseduze kokudla okwamukelekayo kwabantu nsuku zonke ... lapho ukuvezwa kwesikhathi sokuphila kuqala ngesikhathi sokuphila kwengane, imiphumela yayo ebanga umdlavuza iyanda," kubhala abacwaningi. phakathi Impilo Yemvelo.2
  • Imiphumela yocwaningo lwempilo yango-2010 "iqinisekisa ukuthi [i-aspartame] iyisakhi se-carcinogenic ezindaweni eziningi kumagundane, nokuthi lo mphumela wenziwa ezinhlotsheni ezimbili, amagundane (abesilisa nabesifazane) kanye namagundane (abesilisa)," kusho abacwaningi ku Ijenali YaseMelika Yemithi Yezimboni.3

Abaphenyi baseHarvard ngo-2012 babika ubudlelwano obuhle phakathi kokudla kwe-aspartame kanye nengozi eyengeziwe ye-non-Hodgkin lymphoma ne-myeloma eminingi emadodeni, kanye ne-leukemia kwabesilisa nabesifazane. Okutholakele "kugcina amathuba okuba nomthelela omubi ... kumdlavuza okhethiwe" kepha "akuvumeli isinqumo esiphume njengenhlanhla," kubhala abacwaningi ku I-American Journal of Nutrition Clinic.4

Encazelweni ka-2014 ku Ijenali yaseMelika Yemithi Yezimboni, Abaphenyi be-Maltoni Center babhala ukuthi izifundo ezithunyelwe yi-GD Searle ukuze zivunyelwe emakethe “azihlinzeki ngosizo olwanele lwesayensi kwezokuphepha [kwe-aspartame]. Ngokuphambene nalokho, imiphumela yakamuva ye-life-span carcinogenicity bioassays kumagundane namagundane ashicilelwe kumajenali abuyekezwa ngontanga, kanye nocwaningo olulindelekile lwe-epidemiological, lunikeza ubufakazi obungaguquguquki bamandla we-carcinogenic [aspartame]. Ngokwesisekelo sobufakazi bemiphumela engaba khona ye-carcinogenic… ukuvuselelwa kabusha kwesimo samanje sezinhlangano ezilawula umhlaba wonke kufanele kuthathwe njengendaba ephuthumayo yezempilo yomphakathi. ”5

Brain izimila

Ngo-1996, abacwaningi babika ku- Ijenali yeNeuropathology & Yokuhlola Neurology kubufakazi besifo esixhuma ukwethulwa kwe-aspartame ekwandeni kohlobo olunolaka lwamathumba anobuchopho. "Uma kuqhathaniswa nezinye izinto ezithinta ezemvelo ezixhunyaniswe nezicubu zobuchopho, i-aspartame yokufakelwa ingumlingisi othembisayo ochaza ukwanda kwamuva kwesimo kanye nezinga lokulimala kwezicubu zobuchopho… Siphetha ngokuthi kunesidingo sokuhlaziya amandla we-aspartame we-carcinogenic."6

  • Isazi sezinzwa uDkt John Olney, ongumlobi oholayo wocwaningo, utshele Imizuzu engama-60 ngo-1996: “Kube nokwanda okumangazayo kwezehlakalo zamathumba anobuchopho (eminyakeni emithathu kuya kwemihlanu kulandela ukuvunyelwa kwe-aspartame)… kunesisekelo esanele sokusola i-aspartame ukuthi kumele ihlolwe kabusha. I-FDA idinga ukuyihlola kabusha, kulokhu, i-FDA kufanele ikwenze kahle. ”

Izifundo zakuqala ze-aspartame ngawo-1970 zathola ubufakazi bamathumba obuchopho ezilwaneni zaselebhu, kepha lezo zifundo azilandelwanga.

Izifo Zezinhliziyo 

Ukuhlaziywa kwemeta kwe-2017 kocwaningo kuma-sweeteners wokufakelwa, okushicilelwe ku- I-Canadian Medical Association Journal, abutholanga bufakazi obucacile bezinzuzo zokwehlisa isisindo samaswidi okufakelwa ezivivinyweni zomtholampilo ezingahleliwe, futhi wabika ukuthi izifundo zeqoqo zihlobanisa okokunandisa okufakelwayo “nokwenyuka kwesisindo nobukhulu besinqe, kanye nezinga eliphezulu lokukhuluphala, umfutho wegazi ophakeme, isifo se-metabolic, uhlobo lwesifo sikashukela sohlobo 2 nenhliziyo nenhliziyo imicimbi. ”7 Bona futhi:

  • "Izithasiselo zokwenziwa azisizi ekwehliseni isisindo futhi zingaholela ekutholeni amakhilogremu," nguCatherine Caruso, STAT (7.17.2017)
  • "Kungani omunye udokotela wenhliziyo ephuze isiphuzo sakhe sokugcina sokudla," nguHarlan Krumholz, IWall Street Journal (9.14.2017)
  • “Lo dokotela wenhliziyo ufuna umndeni wakhe unciphise i-diet soda. Ingabe eyakho kufanele nayo? ” by UDavid Becker, MD, UPhilly Enquirer (9.12.2017)

 Iphepha le-2016 ku I-Physiology nokuziphatha kubika, “kukhona ukuhlangana okuvusa amadlingozi phakathi kwemiphumela yocwaningo lwezilwane kanye nenqwaba yezifundo ezinkulu, zesikhathi eside zokuhlola kubantu, ekutholeni ukukhuphuka kwesisindo, ukuthambekela, ukubhebhetheka kokukhuluphala, ingozi ye-cardiometabolic, kanye nokufa okuphelele phakathi kwabantu abantu abanokuchayeka okungapheli, nsuku zonke kumakhemikhali anekhalori eliphansi - futhi le miphumela iyakhathaza. ”8

Abesifazane abaphuza iziphuzo ezingaphezu kwezimbili zokudla ngosuku “babenobungozi obukhulu bezifo [zenhliziyo nemithambo yegazi]… [isifo senhliziyo nemithambo yegazi] ukufa… kanye nokufa jikelele,” ngokocwaningo lwango-2014 lweWomen Health Initiative olushicilelwe ku I-Journal of General Medicine Internal.9

Unhlangothi, Dementia kanye Izifo ze-Alzheimer

Abantu abaphuza i-soda yokudla nsuku zonke cishe babenamathuba aphindwe kathathu okuba nesifo sohlangothi nesokuwohloka komqondo njengalabo abasiphuza masonto onke noma ngaphansi. Lokhu kufaka ingozi enkulu yokushaywa yischemic, lapho kuthinteka khona imithambo yegazi ebuchosheni, kanye nesifo sengqondo i-Alzheimer's dementia, okuyindlela ejwayelekile yokuwohloka komqondo, kubika i Ucwaningo luka-2017 eStroke.10

  • Bona futhi: Ividiyo yaseBoston University School of Medicine ocwaningweni olwenziwe yisazi sezinzwa uMatthew Pase, “Ukusetshenziswa Kwansuku Zonke KwamaSodas, Iziphuzo Zezithelo kanye Nama-Sodas Okungelona Owenziwe Kuthinta Ingqondo.”
  • "Ucwaningo luxhumanisa i-diet soda engcupheni ephezulu yokushaywa yisifo sohlangothi, ukuwohloka komqondo," nguFred Barbash, IWashington Post (4.21.2017)

Emzimbeni, i-methyl ester ese-aspartame ihlangana nayo i-methanol bese-ke ingaguqulwa ibe yi-formaldehyde, exhunywe nesifo i-Alzheimer's. Ucwaningo oluyizingxenye ezimbili olushicilelwe ngo-2014 ku I-Journal yezifo ze-Alzheimer kuxhunyaniswe nokuchayeka kwe-methanol engapheli ekulahlekelweni kwememori kanye nezimpawu ze-Alzheimer's Disease kumagundane nezinkawu.

  • "Amagundane aphethwe yi-ethanol anikezwe izimpawu ezifana ne-AD… Lokhu okutholakele kunezela ebuningini obukhulayo bobufakazi obuxhumanisa i-formaldehyde ne- [Alzheimer's disease] pathology." (Ingxenye 1)11
  • "Ukudla [i-ethanol] kudale ushintsho oluhlala isikhathi eside noluphikelelayo lwezifo olwaluhlobene [nesifo i-Alzheimer's]… lokhu okutholakele kusekela ubufakazi obandayo obuxhumanisa i-methanol ne-metabolite formaldehyde yayo [isifo se-Alzheimer's] pathology." (Ingxenye 2)12

ukuquleka

“I-Aspartame ibonakala inyusa inani le-EEG spike wave ezinganeni ezinokuquleka okungekho. Izifundo ezengeziwe ziyadingeka ukuthola ukuthi ngabe lo mphumela wenzeka ngamanani aphansi nakwezinye izinhlobo zokuquleka, ”ngokocwaningo olwenziwe ngo-1992 ku Neurology.13

I-Aspartame “inomsebenzi okhuthaza ukuquleka ezinhlobonhlobo zezilwane ezisetshenziswa kakhulu ukuthola izinto ezithinta… izehlakalo zokubanjwa,” ngokocwaningo lwango-1987 ku Impilo Yemvelo.14

Ukweqiwa okuphezulu kakhulu kwe-aspartame “kungaphazamisa namathuba okuhlaselwa ngabantu abangenazimpawu kodwa abangenayo,” ngokusho kocwaningo olwenziwe ngo-1985 I-Lancet. Ucwaningo luchaza abantu abadala abathathu ababephilile ngaphambili ababenesifo sokuwa okukhulu ngesikhathi besebenzisa imithamo ephezulu ye-aspartame.15

I-Neurotoxicity, Ukulimala kobuchopho kanye nokuphazamiseka kwemizwelo

I-Aspartame ixhunyaniswe nezinkinga zokuziphatha nezokuqonda kubandakanya nezinkinga zokufunda, ikhanda, ukuquleka, i-migraines, imizwa ecasulayo, ukukhathazeka, ukudangala, nokuqwasha, kubhale abacwaningi besifundo se-2017 ku I-Neuroscience Yezempilo. "Ukusetshenziswa kwe-Aspartame kudinga ukuthintwa ngokuqapha ngenxa yemiphumela engaba khona empilweni ye-neurobehavioral."16

“I-aspartame yomlomo ishintshe kakhulu ukusebenza, isimo sokulwa ne-oxidant kanye ne-morphology ye-hippocampus kumagundane; futhi, kungenzeka ukuthi idale i-hippocampal neurogenesis yabantu abadala, ”kubika ucwaningo lwango-2016 I-Neurobiology yokufunda neyeMemori.17 

“Phambilini, kuye kwabikwa ukuthi ukusetshenziswa kwe-aspartame kungadala ukuphazamiseka kwemizwa nokuziphatha kubantu ababucayi. Ukuphathwa yikhanda, ukuqwasha nokuquleka nakho kungeminye yemithelela yezinzwa eke yabhekana nayo, ”kusho ucwaningo olwenziwe ngo-2008 ku I-European Journal ye-Clinical Nutrition. "Siphakamisa ukuthi ukungenisa ngokweqile kwe-aspartame kungabandakanyeka ekutholakaleni kwezifo ezithile zengqondo… kanye nasekufundeni okweqile nasekusebenzeni ngokomzwelo."18 

"(N) izimpawu zezemvelo, kufaka phakathi izinqubo zokufunda nezinkumbulo, kungenzeka zihlobene nokugxila okuphezulu noma okunobuthi kwe-sweetener [aspartame] metabolites," kusho ucwaningo lwango-2006 ku Ucwaningo lwezokwelapha.19

I-Aspartame "ingaphazamisa ukugcinwa kwememori futhi ilimaze ama-hypothalamic neurons kumagundane amadala," ngokusho kocwaningo lwamagundane lwango-2000 olushicilelwe ku Izincwadi Zobuthi.20

"(Mina) nabantu abanezinkinga zemizwelo bazwela kakhulu kulesi sithambisi sokuzenzela futhi ukusetshenziswa kwaso kulesi sibalo kufanele kungadikibali," kusho ucwaningo lwango-1993 kwiphephandaba. Ijenali ye-Biological Psychiatry.21

Ukweqiwa okuphezulu kwe-aspartame “kungadala ushintsho olukhulu emithanjeni yegazi,” kubika ucwaningo olwenziwa ngo-1984 I-American Journal of Nutrition Clinic.22

Ukuhlolwa kukhombise ukulimala kobuchopho kumagundane ezingane kulandela ukungeniswa ngomlomo kwe-aspartate, futhi kukhombisa ukuthi "i-aspartate [inobuthi] kubuthi begundane ezinganeni emazingeni aphansi kakhulu okudla ngomlomo," kubike ucwaningo lwango-1970 ku Nature.23

Izinsizwa ze-Head and Migraines

“I-Aspartame, isiphuzo esidumile sokudla, ingacasula ikhanda kwabanye abantu abasengozini. Lapha, sichaza izigameko ezintathu zabesifazane abasebasha abane-migraine ababika ukuthi bangaphathwa yikhanda ngokuhlafuna inhlaka engenashukela equkethe i-aspartame, ”kusho iphephandaba lango-1997. Ikhanda Journal.24

Isivivinyo se-crossover ngokuqhathanisa i-aspartame ne-placebo eshicilelwe ngo-1994 ku Neurology, “Inikeza ubufakazi bokuthi, phakathi kwabantu abanezinhlungu zokuzibika eziphathwa ikhanda ngemuva kokuminza i-aspartame, i-subset yaleli qembu ibika amakhanda amaningi lapho ihlolwa ngaphansi kwezimo ezilawulwayo. Kubonakala sengathi abanye abantu bathinteka kakhulu ekhanda elibangelwa i-aspartame futhi bangafuna ukunciphisa ukusetshenziswa kwabo. ”25

Ucwaningo lweziguli eziyi-171 eMontefiore Medical Center Headache Unit luthole ukuthi iziguli ezine-migraine “zibike i-aspartame njenge-precipitant kaninginingi ngokuphindwe kathathu kunalezo ezinezinye izinhlobo zekhanda… Siphetha ngokuthi i-aspartame ingaba yinto ebalulekile yokudla ikhanda kwabanye abantu, ”1989 isifundo ku Ikhanda Journal.26

Isivivinyo se-crossover ngokuqhathanisa i-aspartame ne-placebo kumvamisa namandla we-migraines "kukhombise ukuthi ukungena kwe-aspartame ngama-migraineurs kubangele ukwanda okukhulu kokuvama kwekhanda kwezinye izifundo," kubike ucwaningo lwango-1988 ku Ikhanda Journal.27

Umsebenzi Wezinso Uyancipha

Ukusetshenziswa kwezinsizakalo ezingaphezu kwezimbili ngosuku lwesoda eyenziwe ngoshukela “kuhlotshaniswa nokungezwani okuphindwe kabili kokuncipha kokusebenza kwezinso kwabesifazane,” ngokocwaningo lwango-2 ku I-Clinical Journal ye-American Society of Nephrology.28

Ukuzuza Isisindo, Ukudla okwengeziwe kanye nokukhuluphala Izinkinga Ezihlobene

Izifundo eziningana zixhumanisa i-aspartame nokuzuza kwesisindo, ukwanda kwesifiso sokudla, isifo sikashukela, ukuwohloka komzimba kanye nezifo ezihlobene nokukhuluphala. Bona iphepha lethu lamaqiniso: Ukudla kweSoda Chemical Okuboshwe Ekuzuzeni Isisindo.

Le sayensi exhumanisa i-aspartame nokuzuza kwesisindo nezifo ezihlobene nokukhuluphala iphakamisa imibuzo mayelana nokuba semthethweni kwemikhiqizo equkethe i-aspartame njengokudla "noma izinsiza zokwehlisa isisindo. Ngo-2015, i-USRTK ifake isicelo se- Federal Trade Commission futhi FDA ukuphenya ngezindlela zokumaketha nezokukhangisa zemikhiqizo “yokudla” equkethe ikhemikhali elixhumene nokuzuza kwesisindo. Bheka izindaba ezihlobene ukumboza, impendulo evela ku-FTC, Futhi impendulo evela ku-FDA.

Isifo Sikashukela kanye Ne-Metange Derangement

I-Aspartame ihlukaniswa ngokwengxenye ibe yi-phenylalanine, ephazamisa ukusebenza kwe-enzyme emathunjini ane-alkaline phosphatase (IAP) ebikhonjiswe phambilini ukuvimbela isifo se-metabolic syndrome (iqembu lezimpawu ezihambisana nohlobo 2 lwesifo sikashukela nesifo senhliziyo) ngokusho kocwaningo lwango-2017 ku I-Physiology esetshenzisiwe, Ukudla okunomsoco kanye neMetabolism. Kulolu cwaningo, amagundane athola i-aspartame emanzini abo okuphuza athola isisindo esiningi futhi athuthukisa ezinye izimpawu zesifo se-metabolic kunezilwane ezondla izidlo ezifanayo ezingenayo i-aspartame. Ucwaningo luphetha ngokuthi, "Imiphumela yokuvikela i-IAP maqondana ne-metabolic syndrome ingahle ivinjelwe yi-phenylalanine, i-metabolite ye-aspartame, mhlawumbe echaza ukungabi bikho kwesisindo esilindelekile kanye nokwenza ngcono umzimba okuhambisana neziphuzo zokudla."29

Abantu abadla njalo iziswidi zokufakelwa basengozini enkulu yokuthola “isisindo ngokweqile, isifo se-metabolic, uhlobo lwesifo sikashukela sesibili, nesifo senhliziyo,” ngokusho kokubuyekezwa kwe-Purdue ka-2 eminyakeni engaphezu kwengu-2013 eyashicilelwa ku Amathrendi ku-Endocrinology & Metabolism.30

Ocwaningweni olwalandela abesifazane abangama-66,118 eminyakeni engaphezu kwengu-14, zombili iziphuzo ezinoshukela kanye neziphuzo ezenziwe ngobumnandi zihlotshaniswa nengozi yesifo sikashukela soHlobo 2. “Izindlela eziqinile zokubeka engcupheni i-T2D ziphinde zabonwa kuwo wonke ama-quartiles e- ukusetshenziswa kwalezi zinhlobo zombili zesiphuzo… Akukho nhlangano eye yabonwa nge-100% yeziphuzo zezithelo, ”kubika ucwaningo lwango-2013 olushicilelwe ku- I-American Journal of Nutrition Clinic.31

I-Dysbiosis yamathumbu, i-Metabolic Derangement ne-Obesity

Ama-sweeteners okufakelwa angadala ukungabekezelelani kwe-glucose ngokuguqula i-gut microbiota, ngokusho kwe-a Ucwaningo luka-2014 eMvelweni. Abaphenyi babhala, “imiphumela yethu ixhumanisa ukusetshenziswa kwe-NAS [okungeyona ikhalori elenziwe ngeswidi], i-dysbiosis kanye nokungajwayelekile komzimba, ngaleyo ndlela kudinga ukuhlolwa kabusha kokusetshenziswa okukhulu kwe-NAS… Ukuthola kwethu kuphakamisa ukuthi i-NAS kungenzeka ibe negalelo ngqo ekuqiniseni ubhadane ngqo [ukukhuluphala] ukuthi zona ngokwazo zazihloselwe ukulwa. ”32

  • Bheka futhi: “Ama-Artificial Sweeteners Angashintsha Amabhaktheriya EmiGodini Ngezindlela Eziyingozi,” ngu-Ellen Ruppel Shell, I-Scientific American (4.1.2015)

Ucwaningo lwango-2016 ku I-Physiology esetshenzisiwe Nutrition kanye neMetabolism kubika, "Ukudla kwe-Aspartame kube nomthelela omkhulu ebudlelwaneni obuphakathi kwesisindo somzimba (i-BMI) nokubekezelelana koshukela… ukusetshenziswa kwe-aspartame kuhlotshaniswa nokukhubazeka okukhulu okuhlobene nokukhuluphala ekubekezeleni kweglucose."33

Ngokuya ngocwaningo lwamagundane lwango-2014 ku I-PLOS ONE, “I-aspartame inyuse amazinga e-glucose azila ukudla kanye nokuhlolwa kokubekezelelana kwe-insulin kukhombise i-aspartame ukukhubaza ukulahlwa kwe-glucose okuvuselelwe i-insulin… Ukuhlaziywa kwe-fecal kokuqanjwa kwamabhaktheriya esiswini kukhombise i-aspartame ukukhulisa amabhaktheriya aphelele…”34

 Ukukhulelwa Okungajwayelekile: Ukuzalwa Kwangaphambi kwesikhathi 

Ngokuya ngocwaningo lwango-2010 lweqembu lama-59,334 labesifazane abakhulelwe baseDenmark elishicilelwe ku I-American Journal of Nutrition Clinic, "Bekukhona ukuhlangana phakathi kokutholwa kweziphuzo ezibandayo ezenziwe ngoshukela nezingezona ezekhaboni kanye nengozi enkulu yokulethwa ngaphambi kwesikhathi." Ucwaningo luphethe ngokuthi, "Ukuphuza nsuku zonke iziphuzo ezithambile ezinoshukela kungenza ingozi yokulethwa ngaphambi kwesikhathi."35

  • Bheka futhi: "I-Downing Diet Soda Iboshelwe Ekuzalweni Ngaphambi Kokuzalwa," ngu-Anne Harding, I-Reuters (i-7.23.2010)

Izingane Ezikhuluphele

Ukusetshenziswa kwesiphuzo esenziwe ngobuciko ngesikhathi sokukhulelwa kuxhunyaniswe nenkomba yomzimba ephezulu yezingane, ngokusho kocwaningo lwango-2016 I-JAMA Pediatrics. "Ngokwazi kwethu, sinikeza ubufakazi bokuqala bomuntu bokuthi ukusetshenziswa komama okokunandisa okokufakelwa ngesikhathi sokukhulelwa kungathonya i-BMI yezinsana," kubhala abacwaningi.36

  • Bheka futhi: "I-Diet Soda Ekukhulelweni Ixhunyaniswe Nezingane Ezikhuluphele ngokweqile," nguNicholas Bakalar, INew York Times (5.11.2016)

Ukuya esikhathini kokuqala

I-National Heart, Lung, ne-Blood Institute Growth and Health Study ilandele amantombazane we-1988 iminyaka eyishumi ukuhlola izinhlangano ezingaba phakathi kokudla ushukela one-caffeine nongeyona i-caffeine- neziphuzo ezithambile ezenziwe ngobumnandi kanye nokuya esikhathini kokuqala. "Ukusetshenziswa kweziphuzo ezithambile ezine-caffeine nezenziwe ngoshukela bekuhlanganiswa nobungozi bokushesha ukuya esikhathini eqenjini laseMelika lamantombazane ase-Afrika aseMelika naseCaucasus," kuphetha ucwaningo olushicilelwe ngo-10 ku Ijenali ye-American Clinical Nutrition.37

Ukulimala Kwesidoda

"Ukwehla okuphawulekayo ekusebenzeni kwesidoda kwezilwane eziphathwa njenge-aspartame kubonwe uma kuqhathaniswa nokulawulwa kanye nokulawulwa kwe-MTX," ngokusho kocwaningo lwango-2017 ku I-International Journal of Impotence Research. "... Lokhu okutholakele kukhombisa ukuthi ama-aspartame metabolites angaba nomthelela ekuthuthukiseni ukucindezeleka okwenziwe nge-oxidative ku-epididymal sperm."38

Ukulimala Kwesibindi Nokuqedwa KweGlutathione

Ucwaningo lwegundane olushicilelwe ngo-2017 ngo I-Redox Biology kubika, "Ukuphathwa okungapheli kwe-aspartame… kubangele ukulimala kwesibindi kanye namazinga anciphisiwe we-glutathione ancishisiwe, i-glutathione ene-oxidized, i-γ-glutamylcysteine, kanye ne-metabolites eminingi yendlela ye-trans-sulphuration…"39

Ucwaningo lwamagundane olushicilelwe ngo-2017 ngo Ucwaningo Lokudla kutholakale ukuthi, “Ukudla okuphuzwayo okungatheni noma i-aspartame okubangelwe kakhulu yi-hyperglycemia kanye ne-hypertriacylglycerolemia… Kutholakale izinguquko ezimbalwa zesakhiwo se-cytoarchitecture esibindini, kufaka phakathi ukonakala, ukungena, i-necrosis, ne-fibrosis, ikakhulu i-aspartame. Le mininingwane iphakamisa ukuthi ukuphuza isikhathi eside isiphuzo esiphuzo noma ukulimala kwe-aspartame okubangelwa i-aspartame kungahle kulandelwe ngokufakwa kwe-hyperglycemia, ukuqongelela i-lipid, kanye nengcindezi ye-oxidative ngokubandakanyeka kwama-adipocytokines. ”40

Isexwayiso sabantu abasengozini

Ukubuyekezwa kwemibhalo yango-2016 kuma-sweeteners okufakelwa ku- I-Indian Journal ye-Pharmacology kubika, “kukhona okungahambelani ubufakazi bokusekela iningi lokusetshenziswa kwabo kanye nolunye ucwaningo lwamuva luye lwaveza nokuthi lezi zinzuzo ebezikhona ngaphambili… kungenzeka zingabi yiqiniso. ” Abantu abasolayo njengabesifazane abakhulelwe nabancelisayo, izingane, abanesifo sikashukela, i-migraine kanye neziguli ezinesifo sokuwa “kufanele basebenzise le mikhiqizo ngokuqapha okukhulu.”41

Imizamo Yezimboni PR namaqembu angaphambili 

Kusukela ekuqaleni, i-GD Searle (kamuva iMonsanto neNutraSweet Company) basebenzise amaqhinga e-PR anolaka ukumaketha i-aspartame njengomkhiqizo ophephile. Ngo-Okthoba 1987, uGregory Gordon kubikwe ku-UPI:

"INutraSweet Co. ibuye ikhokhe imali efinyelela ku- $ 3 million ngonyaka ngomzamo wokuxhumana nomphakathi wabantu abayi-100 ngamahhovisi aseChicago eBurson Marsteller, owake wasebenza enkampanini ye-PR eNew York. Isisebenzi sathi uBurson Marsteller uqashe ososayensi nodokotela abaningi, imvamisa eba ngu- $ 1,000 XNUMX ngosuku, ukuvikela isinambitheka ezingxoxweni zabezindaba nakwezinye izinkundla zomphakathi. UBurson Marsteller wenqabile ukuxoxa ngezinto ezinjalo. ”

Ukubika kwakamuva okususelwa emibhalweni yangaphakathi embonini kuveza ukuthi izinkampani zeziphuzo ezinjengeCoca-Cola nazo zikhokhela kanjani izithunywa ezivela eceleni, kufaka phakathi odokotela nososayensi, ukuthi bathuthukise imikhiqizo yabo futhi basuse icala lapho isayensi ibophezela imikhiqizo yabo ezinkingeni ezinkulu zempilo.

Bona ukubikwa kuka-Anahad O'Connor kufayela le- New York Times, UCandice Choi kufayela le- Associated Press, nokutholakele kusuka ku- Uphenyo lwe-USRTK mayelana nenkulumo-ze yomkhakha kashukela nemikhankaso yokunxenxa.

Izindatshana zezindaba mayelana nemikhankaso ye-PR embonini yesoda:

Buka konke izindaba zezindaba mayelana ne-aspartame:

AmaSpredishithi Eqiniso e-USRTK

Imibiko ngamaqembu angaphambili nemikhankaso ye-PR

Izinkomba Zesayensi

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[41] USharma A, u-Amarnath S, uThulasimani M, uRamaswamy S. "Izithasiselo zokwenziwa njengezinto ezithatha indawo kashukela: Ingabe ziphephile ngempela?" I-Indian J Pharmacol 2016; 48: 237-40 (esihlokweni)

Ucwaningo olusha lungeza ubufakazi bokuthi ukhula olubulala ukhula luphazamisa ama-hormone

Phrinta imeyili Ungahlukıselana Ephathwayo

Ucwaningo olusha lungeza ubufakazi obukhathazayo ekukhathazekeni kokuthi ukubulala ukhula okusetshenziswa kabanzi ikhemikhali glyphosate angaba namandla okuphazamisa ama-hormone abantu.

Ephepheni elishicilelwe ephephabhukwini I-Chemosphere okubizwa ngokuthi IGlyphosate nezimpawu ezibalulekile zokuphazamiseka kwe-endocrine: Ukubuyekezwa, abathathu bososayensi baphetha ngokuthi i-glyphosate ibonakala inezici ezisemqoka eziyisishiyagalombili kwezilishumi ezihambisana i-endocrine ephazamisa amakhemikhali . Ababhali baxwayisile, nokho, ukuthi izifundo ezizayo zamaqoqo zisadingeka ukuqonda kahle imithelela ye-glyphosate ohlelweni lomuntu lwe-endocrine.

Ababhali, uJuan Munoz, Tammy Bleak noGloria Calaf, ngamunye ohlangene neYunivesithi yaseTarapacá eChile, uthe iphepha labo libuyekeza okokuqala ukuhlanganisa ubufakazi bemishini ku-glyphosate njenge-endocrine-disruptting chemical (EDC).

Obunye bobufakazi bukhombisa ukuthi i-Roundup, i-herbicide eyaziwayo esekwe eMonsanto, ingaguqula i-biosynthesis yamahomoni ezocansi, ngokusho kwabaphenyi.

Ama-EDC angalingisa noma aphazamise amahomoni omzimba futhi axhumene nezinkinga zokukhula nezokuzala kanye nokungasebenzi kahle kobuchopho namasosha omzimba.

Leli phepha elisha lilandela ukushicilelwa ekuqaleni konyaka ukuhlanganiswa kwezifundo zezilwane okukhombise ukuvezwa kwe-glyphosate kunomthelela ezithweni zokuzala futhi kusongela ukuzala.

IGlyphosate yi-herbicide esetshenziswa kakhulu emhlabeni, edayiswa emazweni ayi-140. Yangeniswa ngokuthengisa ngonyaka we-1974 ngabakwaMonsanto Co, ikhemikhali liyisithako esisebenzayo emikhiqizweni ethandwayo efana neRoundup kanye namakhulu abanye ababulali bokhula abasetshenziswa ngabathengi, omasipala, izinsiza, abalimi, abasebenzisa igalofu, nabanye emhlabeni jikelele.

UDana Barr, uprofesa wase-Emory University eRollins School of Public Health, uthe ubufakazi “buvame ukuveza ngokusobala ukuthi i-glyphosate ine-endocrine ephazamisa izakhiwo.”

“Akuyona into engalindelekile ngoba i-glyphosate inokufana okuthile kwesakhiwo namanye ama-endocrine aphazamisa ukubulala izinambuzane; kodwa-ke, ikhathaza kakhulu ngoba ukusetshenziswa kwe-glyphosate kudlula kude eminye imithi yokubulala izinambuzane, ”kusho uBarr, oqondisa uhlelo esikhungweni sokucwaninga ngokuvezwa kwabantu esixhaswe yiNational Institutes of Health esikhishwe e-Emory. "IGlyphosate isetshenziswa ezitshalweni eziningi kakhulu nasezicelweni eziningi zokuhlala ezinjengokuchayeka kokuqoqeka nokuqoqekayo kungabonakala."

Phil Landrigan, umqondisi weGlobal Observatory on Pollution and Health, kanye noprofesa wesayensi yezinto eziphilayo
eBoston College, uthe ukubuyekeza kudonse ndawonye "ubufakazi obuqinile" bokuthi i-glyphosate iyisiphazamisi se-endocrine.

“Umbiko uhambisana nenqwaba yezincwadi ezibonisa ukuthi i-glyphosate inemiphumela engemihle yezempilo - okutholakele okuguqula isikhathi eside sokusebenza kukaMonsanto ukuvezwa kwe-glyphosate njengekhemikhali enobungozi engenayo imithelela emibi empilweni yabantu, ”kusho uLandrigan.

Ama-EDC bekuyinto ekhathazayo kusukela ngama-1990s ngemuva kochungechunge lwezincwadi eziphakamise ukuthi amanye amakhemikhali asetshenziswa kakhulu kuma-pesticides, izinyibilikisi zezimboni, amapulasitiki, okokuhlanza, nezinye izinto angaba namandla okuphazamisa ukuxhumana phakathi kwamahomoni nama-receptors awo.

Ososayensi ngokuvamile babona izakhiwo eziyishumi ezisebenzayo zama-ejenti aguqula isenzo se-hormone, ebhekisa kulezi njengezici eziyishumi "eziyinhloko" zabaphazamisi be-endocrine. Izici eziyishumi zimi kanje:

Ama-EDC anga:

  • Ukusatshalaliswa kwama-hormone okuguqula amazinga wokujikeleza kwamahomoni
  • Yenza ushintsho ku-hormone metabolism noma imvume
  • Guqula isiphetho samaseli akhiqiza ama-hormone noma aphendula nge-hormone
  • I-Alter hormone receptor expression
  • Hlanganisa ama-hormone receptors
  • Hlanganyela noma usebenze ama-hormone receptors
  • Ukudluliswa kwesiginali eguquguqukayo kumaseli aphendula ama-hormone
  • Yenza ukuguqulwa kwe-epigenetic kumaseli akhiqiza ama-hormone noma aphendula ama-hormone
  • Alter hormone synthesis
  • Ukuhambisa ama-hormone okuhamba ngaphesheya kwezingqamuzana zeseli

Ababhali bephepha elisha bathe ukubuyekezwa kwemininingwane yemishini kukhombisile ukuthi i-glyphosate ihlangabezane nazo zonke izici ezibalulekile ngaphandle kwezimbili: "Mayelana ne-glyphosate, abukho ubufakazi obuhambisana namandla aphikisayo ama-hormonal receptors," kusho bona. Futhi, "abukho ubufakazi bokuthi kunomthelela ekuguqulweni kwamahomoni noma ekususweni," ngokusho kwabalobi.

Ucwaningo olwenziwe emashumini ambalwa edlule lubhekise kakhulu kwizixhumanisi ezitholakala phakathi kwe-glyphosate nomdlavuza, ikakhulukazi i-non-Hodgkin lymphoma (NHL.) Ngo-2015, i-World Health Organization's International Agency for Research on Cancer i-glyphosate ehlukanisiwe njenge-carcinogen yabantu.

Bangaphezu kuka-100,000 abantu bamangalele uMonsanto e-United States okusolwa ukutholakala kwemithi yokubulala ukhula egxilwe enkampanini ye-glyphosate kubangele bona noma abathandekayo babo ukuba bathuthukise i-NHL.

Abamangali ecaleni lamacala ezweni lonke bathi iMonsanto sekuyisikhathi eside ifuna ukufihla izingozi zemithi yayo yokubulala ukhula. IMonsanto ilahlekelwe izivivinyo ezintathu kwezintathu kanti umnikazi wayo waseGerman uBayer AG usebenzise unyaka nohhafu odlule uzama ukuhlala amacala aphume enkantolo.

Ababhali bephepha elisha baqaphela ubuningi be-glyphosate, bethi "ukusetshenziswa okukhulu" kwaleli khemikhali "kuholele ekusakazekeni kwemvelo okubanzi," kufaka phakathi ukuvezwa okukhulayo okuxhumene nokusetshenziswa komuntu kombulali wokhula ngokudla.

Abaphenyi bathi yize abalawuli bethi amazinga ezinsalela ze-glyphosate atholakala kakhulu ekudleni aphansi ngokwanele ukuthi aphephe, "ngeke bakwazi ukubekeka engcupheni" yabantu abadla ukudla okune-chemical, ikakhulukazi okusanhlamvu nezinye izitshalo- ukudla okusekelwe, okuvame ukuba namazinga aphezulu kunobisi, inyama noma imikhiqizo yenhlanzi.

Imibhalo kahulumeni wase-US ikhombisa ukuthi izinsalela ze-glyphosate zitholakele ezinhlotsheni eziningi zokudla, kufaka phakathi uju oluphilayo, Futhi i-granola nabaqhekezi.

Abaphenyi bakahulumeni waseCanada nabo babike izinsalela ze-glyphosate ekudleni. Umbiko owodwa okhishwe ngo-2019 ososayensi abavela e-Agri-Food Laboratories yaseCanada e-Alberta Ministry of Agriculture and Forestry bathola i-glyphosate kuma-sampuli ayi-197 kwangu-200 oju abaluhlolayo.

Ngaphandle kokukhathazeka ngemithelela ye-glyphosate empilweni yomuntu, kufaka phakathi nokuchayeka ekudleni, abalawuli base-US bakuvikele ngokuqinile ukuphepha kwamakhemikhali. I- Isikhungo Sokuvikelwa Kwemvelo sigcina ukuthi ayitholakalanga "noma iziphi izingozi empilweni yomuntu ngenxa yokuchayeka ku-glyphosate. ”

Bhalisela incwadi yethu yezindaba. Thola izibuyekezo zamasonto onke ebhokisini lakho lokungenayo.