Amacala we-FOI kuphenyo lwe-biohazards

Phrinta imeyili Ungahlukıselana Ephathwayo

I-US Right to Know, iqembu eliphenya ngempilo yomphakathi elingenzi nzuzo, ifake amacala amathathu emelene nezinhlangano zombuso zokwephula izinhlinzeko ze-Freedom of Information Act (FOIA). Amacala amacala ayingxenye yemizamo yethu yokuthola okwaziwayo ngemvelaphi yenoveli coronavirus SARS-CoV-2, ukuvuza noma ukulimala kumalebhu ezokuvikela, kanye nobungozi bokucwaninga ngomsebenzi okufuna ukukhulisa ukuthinteka noma ukubulala amagciwane angaba khona obhubhane.

Kusukela ngoJulayi, sifake amarekhodi omphakathi angama-48, ombuso kanye nawamazwe omhlaba sicela imininingwane mayelana nemvelaphi yeSARS-CoV-2, kanye nezingozi zamalabhu ezokuphepha kanye nocwaningo lomsebenzi.

Funda kabanzi mayelana okutholakele kwethu kuze kube manje, kungani senza lolu phenyo, ukufundwa okunconyiwe futhi imibhalo esiyitholile.

Amacala we-FOI afakiwe

(1) UMnyango Wezemfundo wase-US: Ngomhlaka 17 Disemba USRTK wafaka icala ngokumelene noMnyango Wezemfundo wase-US ngokwephula izinhlinzeko ze-FOIA. Icala, elifakwe eNkantolo yesiFunda e-US eNyakatho yesiFunda saseCalifornia, lifuna imibhalo uMnyango wezeMfundo oyicelile eNyuvesi YaseTexas 'Medical Branch eGalveston mayelana nezivumelwano zayo zoxhaso kanye nokubambisana kwezesayensi kanye / noma nocwaningo neWuhan Institute of Virology yaseChina.

(2) Umnyango Wombuso wase-US: Ngomhla kaNovemba 30 USRTK wafaka icala ngokumelene noMnyango Wombuso wase-US ngokwephula izinhlinzeko ze-FOIA. Icala, elifakwe eNkantolo yesiFunda e-US eNyakatho yesiFunda saseCalifornia, lifuna imibhalo nezincwadi noma i-Wuhan Institute of Virology yaseChina, iWuhan Center for Disease Control and Prevention, ne-EcoHealth Alliance, ebibambisene futhi ixhasa iWuhan Institute yeVirology, phakathi kwezinye izifundo. Bheka ukukhululwa kwezindaba.

(3) Izikhungo Zezempilo Zikazwelonke: NgoNovemba 5 USRTK wafaka icala elibhekiswe kuNational Institutes of Health (NIH) ngokwephula izinhlinzeko ze-FOIA. Icala, elifakwe eNkantolo yesiFunda e-US eWashington, DC, lifuna ukuxhumana nezinhlangano ezifana ne-Wuhan Institute of Virology kanye ne-Wuhan Center for Disease Control and Prevention, kanye ne-EcoHealth Alliance, ebibambisene futhi ixhasa iWuhan Isikhungo seVirology. Bheka ukukhululwa kwezindaba.

I-US Right to Know iqembu lokucwaninga eliphenya ngokugxila ekubonakaleni kwezempilo yomphakathi. Ukuthola eminye imininingwane ngamacala we-FOI esiwafakile ukufakazela ilungelo lomphakathi lokwazi, bona i- Ikhasi lokumangalelwa kwe-FOIA.

Imibhalo ye-FOI ngemvelaphi ye-SARS-CoV-2, izingozi zokucwaninga ngomsebenzi kanye namalebhu e-biosafety

Phrinta imeyili Ungahlukıselana Ephathwayo

Ilungelo Lethu Lokwazi e-US ngicwaninga ngemvelaphi yeSARS-CoV-2, nobungozi bamalabhoratri okuphepha kanye nokucwaninga ngomsebenzi, okuhlose ukwandisa ukwanda kokutheleleka noma ukubulala kwamagciwane abangelwa ubhubhane. Sithumela izibuyekezo nokutholwa okusha ku- iBiohazards Blog yethu.

Ama-imeyili amasha akhombisa izingxoxo zososayensi zokuxoxa ngemvelaphi yeSARS-CoV-2 

Phrinta imeyili Ungahlukıselana Ephathwayo

Ama-imeyili asanda kuthola anikela amazwibela okuthi ukulandisa kokuqiniseka kuthuthuke kanjani ngemvelaphi yemvelo yenoveli coronavirus SARS-CoV-2, ngenkathi kusala imibuzo ebalulekile yesayensi. Izingxoxo zangaphakathi kanye nohlaka lokuqala lwencwadi yososayensi zikhombisa ochwepheshe bexoxa ngezikhala zolwazi nemibuzo engaphenduliwe ngemvelaphi yelabhu, njengoba abanye bebefuna ukucindezela imibono “engemuva” yokuthi kungenzeka ukuthi leli gciwane livele ebhodini.

Ososayensi abanethonya nezindawo eziningi zezindaba bachaze ubufakazi ngokuthi “nzima”Ukuthi leli gciwane lavela ezilwaneni zasendle, hhayi ebhodini. Kodwa-ke, ngemuva konyaka amacala okuqala abikiwe we-SARS-CoV-2 edolobheni laseChina iWuhan, kuncane okwaziwayo kanjani noma kuphi kwavela igciwane. Ukuqonda umsuka weSARS-CoV-2, obangela isifo i-COVID-19, kungabaluleka ekunqandeni ubhadane olulandelayo.

Ama-imeyili ochwepheshe be-coronavirus USolwazi Ralph Baric - etholwe ngesicelo samarekhodi omphakathi yi-US Right to Know - khombisa izingxoxo phakathi kwabamele iNational Academy of Sciences (NAS), kanye nochwepheshe bokungavikeleki kwezifo ezithathelwanayo emanyuvesi ase-US nase Umanyano we-EcoHealth.

NgoFebhuwari 3, i-White House Office of Science and Technology Policy (OSTP) kubuziwe iNational Academies of Sciences, Engineering and Medicine (NASEM) ukuze “ibize umhlangano wochwepheshe… ukuze kuhlolwe ukuthi iyiphi idatha, ulwazi namasampula adingekayo ukubhekana nokungaziwa, ukuze kuqondwe imvelaphi yokuziphendukela kwemvelo ye-2019-nCoV, futhi iphendule ngempumelelo kokubili ukugqashuka kwanoma yikuphi ukwaziswa okungaqondile okuba umphumela. ”

I-Baric nezinye izazi zezifo ezithathelwanayo zazibandakanyeka ekubhaleni impendulo. Ama-imeyili akhombisa izingxoxo zangaphakathi zochwepheshe kanye ne okusalungiswa kusenesikhathi yangomhla kaFebhuwari 4.

Umbhalo wokuqala wachaza "imibono yokuqala yochwepheshe" ukuthi "imininingwane etholakalayo ye-genomic iyahambisana nokuziphendukela kwemvelo nokuthi okwamanje abukho ubufakazi bokuthi igciwane lenzelwe ukusabalala ngokushesha okukhulu phakathi kwabantu." Lo musho osalungiswa waphakamisa umbuzo, kubakaki: “[cela ochwepheshe ukuthi bangeze imininingwane ethile yamasayithi okubopha?]” Iphinde yafaka umbhalo waphansi kubakaki: ukuvela kwama-coronaviruses ahlobene]. ”

In i-imeyili eyodwa, yangomhla kaFebruwari 4, uchwepheshe wezifo ezithathelwanayo uTrevor Bedford waphawula: “Ngeke ngikhulume ngezindawo zokubopha lapha. Uma uqala ukukala ubufakazi kuningi okufanele ucabange ngakho kuzo zombili lezi zimo. ” Ngazo “zombili lezi zimo,” kubonakala sengathi iBedford ibhekisa kuzimo zelebhu kanye nemvelaphi yemvelo.

Umbuzo wezindawo ezibophezelayo ubalulekile engxoxweni mayelana nemvelaphi yeSARS-CoV-2. Izindawo ezihlukanisayo ezibophayo ku-SARS-CoV-2's spike protein confer “Okuseduze” ukubopha nokungena kwegciwane emangqamuzaneni omuntu, nokwenza i-SARS-CoV-2 itheleleke kakhulu kune-SARS-CoV. Ososayensi baphikise ngokuthi izingosi ezihlukile zokubopha zeSARS-CoV-2 kungenzeka ukuthi zivele ngenxa ye- zemvelo spillover endle noma ngamabomu I-laboratory ukulungisa kabusha kokhokho wemvelo ongakadalulwa okwamanje we-SARS-CoV-2.

The incwadi yokugcina eshicilelwe ngoFebhuwari 6 ayizange isho izingosi ezibophezelayo noma ukuthi kungenzeka ukuthi ivela kulabhorethri. Kuyacaca ukuthi kuneminye imininingwane edingekayo yokuthola umsuka weSARS-CoV-2. Incwadi ithi, “Ochwepheshe basazise ukuthi imininingwane eyengeziwe yokulandelana kwe-genomic evela kumasampula egciwane ngokwendawo - nangokwesikhashana - ayadingeka ukunquma umsuka nokuvela kwegciwane. Amasampula aqoqwe kusenesikhathi ekuqhamukeni kweWuhan namasampula avela ezilwaneni zasendle abaluleke kakhulu. ”

Ama-imeyili akhombisa abanye ochwepheshe bexoxa ngesidingo solimi olucacile ukuphikisana nalokho okuchazwe ngokuthi yi "crackpot theories" yemvelaphi yelabhu. UKristian Andersen, umbhali oholayo we iphepha elinomthelela leMvelo Medicine egomela imvelaphi engokwemvelo ye-SARS-CoV-2, uthe okusalungiswa kwasekuqaleni “kwakukukhulu, kodwa ngiyazibuza ukuthi ngabe sidinga yini ukuqina kakhulu embuzweni wobunjiniyela.” Uqhube wathi, “Uma enye yezinhloso zalo mbhalo kungukuphikisana nalezi zinkolelo-mbono, ngicabanga ukuthi kubaluleke kakhulu ukuthi sikwenze lokho ngokuqinile nangolimi olucacile…”

In impendulo yakhe, IBaric ihlose ukudlulisa isisekelo sesayensi ngemvelaphi yemvelo yakwaSARS-CoV-2. “Ngicabanga ukuthi sidinga ukusho ukuthi isihlobo esiseduze kakhulu naleli gciwane (96%) satholwa kumalulwane azungeza emhumeni waseYunnan, eChina. Lokhu kwenza isitatimende esiqinile ngemvelaphi yezilwane. ”

Okokugcina Incwadi kusuka kubongameli be-NASEM abathathi hlangothi ngemvelaphi yegciwane. Ithi, “Ucwaningo lwezocwaningo ukuqonda kangcono imvelaphi ye-2019-nCoV nokuthi ihlobana kanjani namagciwane atholakala kumalulwane nakwezinye izinhlobo zezinto eseziqalile. Isihlobo esiseduze kakhulu se-2019-nCoV sibonakala njenge-coronavirus ekhonjwe kumasampula athathwe ngamalulwane aqoqwe eChina. ” Incwadi ibhekisiwe ezimbili izifundo lokho kwenziwa yi-EcoHealth Alliance neWuhan Institute of Virology. Zombili ziveza imvelaphi engokwemvelo ye-SARS-CoV-2.

Emasontweni ambalwa kamuva, incwadi kaMongameli yeNASEM yavela njengomthombo onegunya lomuntu onethonya Isitatimende sabososayensi esishicilelwe ku I-Lancet lokho kudlulise isiqiniseko esithe xaxa ngemvelaphi ye-SARS-CoV-2. I-USRTK ibike ngaphambilini ukuthi uMongameli we-EcoHealth Alliance uPeter Daszak wabhala la mazwi, aqinisekisa ukuthi "ososayensi abavela emazweni amaningi… baphetha ngokumangazayo ukuthi le coronavirus yavela ezilwaneni zasendle." Lesi sikhundla, kusho isitatimende, "sisekelwa futhi yincwadi evela kubongameli be-US National Academies of Science, Engineering, and Medicine."

Ukuqokwa okwalandela kukaPeter Daszak nabanye ababambisene ne-EcoHealth Alliance ukuze Ikhomishini yeLancet COVID19 noDaszak kuye Uphenyo lweWorld Health Organisation Imvelaphi yakwaSARS-CoV-2 kusho ukuthi ukwethembeka kwale mizamo kucekelwa phansi ngu ukungqubuzana kwezintshisekelo, nangokubukeka sengathi sebevele behlulele ngaphambi kwalolu daba.

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“Izingqinamba okufanele sizigweme”

Ama-imeyili eBaric akhombisa nomele i-NAS ukuphakamisa kososayensi base-US kufanele “mhlawumbe bagweme” imibuzo emayelana nemvelaphi yakwa-SARS-CoV-2 emihlanganweni yamazwe womabili ababeyihlela nochwepheshe be-Chinese COVID-19. Ama-imeyili ngoMeyi nangoJuni 2020 axoxa ngezinhlelo zemihlangano. Ososayensi ababambe iqhaza baseMelika, iningi labo elingamalungu e-NAS Ikomidi Elimi Ngezifo Ezithathelwanayo Eziqhamukayo Nezinsongo Zempilo Zekhulu Lama-21, kubalwa uRalph Baric, Peter Daszak, David Franz, James Le Duc, Stanley Perlman, David Relman, Linda Saif, noPeiyong Shi.

The ososayensi ababambe iqhaza baseChina kufaka phakathi uGeorge Gao, uZhengli Shi, noZhiming Yuan. UGeorge Gao unguMqondisi we-China CDC. UZhengli Shi uhola ucwaningo lwe-coronavirus eWuhan Institute of Virology, kanti uZhiming Yuan unguMqondisi weWIV.

In i-imeyili kubahlanganyeli baseMelika mayelana neseshini yokuhlela, Isikhulu Sezinhlelo Eziphezulu se-NAS uBenjamin Rusek uchaze inhloso yomhlangano: “ukukugcwalisa ngemvelaphi yengxoxo, xoxa ngezihloko / imibuzo (uhlu kuhlu lwesimemo sakho nokunamathiselwe) nezinkinga okufanele gwema (imibuzo yemvelaphi, ipolitiki)…

Ukuze uthole ukwaziswa okwengeziwe:

Xhumanisa nama-imeyili kaProfesa Ralph Baric wase-University of North Carolina angatholakala lapha: Ama-imeyili eBaric (Amakhasi we-83,416)

I-US Right to Know ithumela imibhalo evela kuzicelo zethu zamarekhodi womphakathi ze uphenyo lwethu lwe-biohazards. Bheka: Imibhalo ye-FOI ngemvelaphi ye-SARS-CoV-2, izingozi zokucwaninga ngomsebenzi kanye namalebhu e-biosafety.

I-EcoHealth Alliance yahlela isitatimende sososayensi abalulekile "ngemvelaphi yemvelo" ye-SARS-CoV-2

Phrinta imeyili Ungahlukıselana Ephathwayo

Ama-imeyili atholwe yi-US Right to Know akhombisa ukuthi a isitatimende ku I-Lancet ebhalwe ososayensi abaqavile bezempilo yomphakathi abangama-27 begxeka "imibono yetulo ephakamisa ukuthi i-COVID-19 ayinayo imvelaphi yemvelo" yahlelwa ngabasebenzi be-EcoHealth Alliance, iqembu elingenzi nzuzo ithole izigidi zamaRandi of Umkhokhi wentela wase-US uxhaso ukuze ukuguqula izakhi zofuzo Ama-coronavirus nososayensi e Isikhungo se-Wuhan se-Virology.

Ama-imeyili atholakele ngezicelo zamarekhodi omphakathi akhombisa ukuthi uMongameli we-EcoHealth Alliance uPeter Daszak wabhala lo mbhalo I-Lancet isitatimende, nokuthi wayehlose ukukwenza "Kungabonakali ukuthi ivela kunoma iyiphi inhlangano noma umuntu oyedwa" kodwa kunalokho kubonakale njenge “Incwadi elula evela kososayensi abaphambili”. UDaszak ubhale ukuthi ufuna "ukugwema ukuvela kwesitatimende sezepolitiki".

Incwadi yososayensi yavela ku I-Lancet ngoFebhuwari 18, kusasele isonto elilodwa nje ukuthi i-World Health Organisation imemezele ukuthi lesi sifo esidalwe yi-novel coronavirus sizobizwa nge-COVID-19.

Ababhali abangama-27 “bayigxeka ngokuqinile imibono yetulo yokuthi i-COVID-19 ayinayo imvelaphi engokwemvelo,” futhi babika ukuthi ososayensi abavela emazweni amaningi “baphetha ngokumangazayo ukuthi le coronavirus yavela ezilwaneni zasendle.” Le ncwadi ibingafaki izinkomba zesayensi zokuphikisa imfundiso-mbumbulu yegciwane. Usosayensi oyedwa, uLinda Saif, ubuze nge-imeyili ukuthi kungasiza yini “Ukufaka isitatimende esisodwa noma ezi-2 ukuxhasa ukuthi kungani i-nCOV kungelona igciwane elenziwa elebhu futhi kuvele ngokwemvelo? Kubonakala kubalulekile ekuphikiseni lokho kushiwo! ” UDaszak uphendule wathi, “Ngicabanga ukuthi kufanele sinamathele esitatimendeni esibanzi. "

Izingcingo ezikhulayo ukuphenya iWuhan Institute of Virology njengomthombo ongaba khona weSARS-CoV-2 kuholele kulokhu ukuhlolwa okwengeziwe we-EcoHealth Alliance. Ama-imeyili akhombisa ukuthi amalungu e-EcoHealth Alliance adlale kanjani indima yokuqala ekubunjweni kwemibuzo mayelana nokuthi kungenzeka yini ukuthi i-SARS-CoV-2 ingavela kanjani njengemibono “edabukisayo edinga ukulungiswa,” njenge UDaszak utshele The Guardian.

Yize ibinzana elithi "EcoHealth Alliance" livele kanye kuphela I-Lancet isitatimende, ngokuhlangana nombhali-mbhali uDaszak, abanye ababhali ababambisene nabo banobudlelwano ngqo neqembu elingadalulwanga njengokushayisana kwezintshisekelo. URita Colwell noJames Hughes banjalo amalungu weBhodi labaQondisi be-EcoHealth Alliance, UWilliam Karesh uyiPhini Likamongameli Ophethe weqembu lezeMpilo neNqubomgomo, futhi Inkambu yeHume ungumeluleki weSayensi neNqubomgomo.

Ababhali besitatimende baphinde bathi "ukwabiwa okusheshayo, okuvulelekile, nokusobala kwemininingwane ngalokhu kuqubuka manje sekusongelwa amahemuhemu nolwazi olungelona iqiniso ngemvelaphi yalo." Namuhla, noma kunjalo, kuncane okwaziwayo mayelana nemvelaphi ye-SARS-CoV-2, kanye nophenyo ngemvelaphi yayo ngo- i-World Health Organization futhi I-Lancet Ikhomishini ye-COVID-19 ziye zaba kusitshekelwe ekusithekeni futhi ngicindezelwe ngu ukungqubuzana kwezintshisekelo.

UPeter Daszak, uRita Colwell, no I-Lancet Umhleli uRichard Horton akazange anikeze imibono ephendula izicelo zethu zale ndaba.

Ukuze uthole ukwaziswa okwengeziwe:

Isixhumanisi seqoqo lonke lama-imeyili e-EcoHealth Alliance singatholakala lapha: Ama-imeyili e-EcoHealth Alliance: University of Maryland (Amakhasi we-466)

I-US Right to Know ithumela imibhalo etholwe ngenkululeko yomphakathi yolwazi (i-FOI) yezicelo uphenyo lwethu lweBiohazards kokuthunyelwe kwethu: Imibhalo ye-FOI ngemvelaphi ye-SARS-CoV-2, izingozi zokucwaninga ngomsebenzi kanye namalebhu e-biosafety.

Kungani sicwaninga ngemvelaphi yeSARS-CoV-2, amalebhu ezokuvikela kanye nocwaningo lwe-GOF

Phrinta imeyili Ungahlukıselana Ephathwayo

Bheka IBiohazards Blog ukuthola izibuyekezo kuphenyo lwethu, futhi siyathumela imibhalo evela kuphenyo lwethu lapha. Bhalisela lapha ukuthola izibuyekezo zamasonto onke. 

NgoJulayi 2020, i-US Right to Know yaqala ukuletha izicelo zamarekhodi omphakathi ngenhloso yokuthola imininingwane evela ezikhungweni zomphakathi ngemizamo yokuthola okwaziwayo ngemvelaphi yenoveli coronavirus SARS-CoV-2, edala lesi sifo i-Covid-19. Selokhu kuqale ukubheduka eWuhan, abakwaSARS-CoV-2 babulale abantu abangaphezu kwesigidi, ngenkathi begulisa ezinye izigidi ngobhadane lomhlaba oluqhubeka nokuvela.

Siphenya nezingozi, ukuvuza nokunye ukwenzeka emalabhorethri lapho kugcinwa khona futhi kuguqulwe izifo ezinamandla eziwubhadane, kanye nezingozi zezempilo zomphakathi zocwaningo lwe-gain-of-function (GOF), olubandakanya ucwaningo lokuthuthukisa izici zokusebenza kwamagciwane abulalayo , njengomthamo wegciwane, ukusuleleka kanye nokusabalalisa.

Umphakathi wesayensi womphakathi nowomhlaba wonke unelungelo lokwazi ukuthi iyiphi idatha ekhona ngalezi zindaba. Sizobika lapha noma yikuphi ukutholakala okuwusizo okungavela ocwaningweni lwethu.

I-US Right to Know iqembu lokucwaninga eliphenya ngokugxila ekubonakaleni kwezempilo yomphakathi.

Kungani senza lolu cwaningo?

Sikhathazekile ngokuthi izinsizakusebenza zokuphepha zikazwelonke e-United States, China nakwezinye izindawo, kanye neyunivesithi, izimboni kanye nezinhlangano zikahulumeni abasebenzisana nazo, kungenzeka zinganikeli isithombe esiphelele nesithembekile ngemvelaphi ye-SARS-CoV-2 nobungozi yocwaningo lokuthola umsebenzi.

Ngocwaningo lwethu, sifuna ukuphendula imibuzo emithathu:

  • Yini eyaziwayo ngemvelaphi yeSARS-CoV-2?
  • Ngabe zikhona izingozi noma iziphithiphithi ezenzekile ezikhungweni zokucwaninga nge-biosafety noma ze-GOF ezingakabikwa?
  • Ngabe kukhona ukukhathazeka mayelana nezingozi zokuphepha eziqhubekayo zamalabhorethri okuphepha noma ucwaningo lwe-GOF olungakabikwa?

Uyini umsuka weSARS-CoV-2?

Ngasekupheleni kukaDisemba 2019, edolobheni laseWuhan, eChina, kwavela izindaba zesifo esibulalayo esithathelwanayo esibizwa nge-COVID-19, esidalwe yiSARS-CoV-2, i-coronavirus yenoveli eyayingaziwa ukuthi ibikhona phambilini. Imvelaphi yeSARS-CoV-2 ayaziwa. Kunemicabango emibili eyinhloko.

Abaphenyi kumanethiwekhi ochwepheshe ahlobene ne Isikhungo se-Wuhan se-Virology (WIV) futhi Umanyano we-EcoHealth, i-US non-profitthat ine kutholwe izigidi zamadola kwizibonelelo ezikhokhelwa ngabakhokhi bentela kuya sebenzisana no I-WIV ocwaningweni lwe-coronavirus, babe ezibhaliwe ukuthi igciwane lenoveli kungenzeka ukuthi yavela ngokukhethwa kwemvelo ezindaweni zezilwane, nge inqolobane yayo kumalulwane. Lokhu "Zoonotic" umsuka i-hypothesis yaphinde yaqiniswa ngu izimangalo ukuthi ukuqubuka okusha kwe-coronavirus kuqale kufayela le- “Izilwane zasendle” emakethe eWuhan, the Imakethe yokudla kwasolwandle yaseHuanan, lapho kungenzeka khona ukuthi kuthengiswe izilwane ezingase zitheleleke. (Noma kunjalo, okungenani ingxenye eyodwa kwezintathu yeqoqo lokuqala leziguli ezinegciwane, kufaka phakathi icala lokuqala elaziwa kakhulu lokutheleleka kusuka ngoDisemba 1, 2019, lalingaxhumananga ngqo noma ngokungaqondile nababekhona emakethe yezilwane zasolwandle yabantu nezilwane.)

I-zoonosis hypothesis njengamanje iyi-hypothesis yemvelaphi ekhona. Kodwa-ke, imvelaphi ye-zoonotic ye-SARS-CoV-2 inayo kepha isazomiswa ngokuqinisekile, futhi abanye abacwaningi baveze ukuthi kusekelwe eziphikisanayo kokuma ukuthi zidinga ukuqhubeka kophenyo.

Ngokuqhubeka nokufunda ngalezi zihloko, bheka uhlu lwethu lokufunda: Uyini umsuka weSARS-CoV-2? Ziyini izingcuphe zokucwaninga ngomsebenzi?

Abanye ososayensi baye basikisela umbono ohlukile wemvelaphi; bacabanga ukuthi i-SARS-CoV-2 ingumphumela we ngengozi ukukhishwa kohlobo lwasendle noma i-lab-modified uhlobo lokuhlobene eduze Igciwane elifana ne-SARS ebigcinwe ezikhungweni zokuvikela ukuphepha ezenza ucwaningo lwe-coronavirus eWuhan, njenge-WIV noma iZikhungo ze-Wuhan zokuLawulwa nokuVinjelwa kwezifo.

Okubaluleke kakhulu, isimo esivela kumalabha asisho ukuthi asiyifaki i-zoonosis hypothesis ngoba i-SARS-CoV-2 ingaba umphumela wokulungiswa kwelebhu okwenziwe ngezinhlobo ezingabikwanga ze-bat coronaviruses ezingabiki ze-SARS igcinwe ku-WIV, noma ukuqoqwa nje kanye nokugcinwa kwama-coronaviruses anjalo. Abagxeki ye-lab-origin hypotheses iyichithile le mibono njenge ukuqagela okungenabufakazi futhi izinkolelo zendlovu.

Kuze kube manje, kukhona hhayi kwanele ubufakazi ukwenqaba ngokuphelele imvelaphi ye-zoonotic noma i-lab-Origin hypotheses. Siyazi, ngokususelwa kuzindatshana zocwaningo ezishicilelwe futhi Izibonelelo zikahulumeni wase-US ku-EcoHealth Alliance yokuxhasa ucwaningo lwe-WIV coronavirus, leyo WIV igcinwe amakhulukhulu wama-coronaviruses angaba yingozi akwa-SARS, futhi enziwe Ukuhlolwa kwe-GOF kuma-coronaviruses ngokubambisana namanyuvesi ase-US, futhi kwakukhona ukukhathazeka ngokuphepha nge I-WIV's BSL-4 laboratory.

Kepha kuze kube manje, akukabi khona ukucwaningwa okuzimele kwamarekhodi kanye nemininingwane yolwazi lweWIV, futhi kunolwazi oluncane mayelana nokusebenza kwangaphakathi kweWIV. I-WIV isusile kwimininingwane yayo yewebhusayithi njenge ukuvakashelwa konozakuzaku besayensi baseMelika ngonyaka wezi-2018, Futhi ivale ukufinyelela kwi-database yayo yamagciwane futhi amarekhodi elabhorethri izivivinyo ze-coronavirus ezenziwa ososayensi be-WIV.

Ukuqonda umsuka weSARS-CoV-2 kunemithelela ebalulekile yenqubomgomo yezinhlelo zomphakathi zezempilo nezokudla. Imvelaphi engaba khona ye-zoonotic yakwaSARS-CoV-2 iyaphakama imibuzo mayelana nezinqubomgomo ezithuthukisa ukunwetshwa kokusebenza kwezolimo ezimbonini kanye nemfuyo, okungaba yizimbangela ezinkulu ze ukuvela kwamagciwane enoveli kanye ne-pathogenic kakhulu, ukugawulwa kwamahlathi, ukulahleka kwezinhlobonhlobo zemvelo kanye nokuhlaselwa kwemvelo. I- kungenzeka ukuthi i-SARS-CoV-2 ingahle ivele kulabhorethri ye-biodefense imibuzo mayelana ukuthi kufanele yini unalezi zinsiza, lapho kugcinwa khona futhi kuguqulwe okwenziwe ngama-microbial pathogen akhiqizwa endle.

Noma ngabe i-SARS-CoV-2 iguqulwe ilebhu noma cha, uphenyo lwelab-origin-theorists luphakamisa imibuzo ebalulekile mayelana nokushoda obala maqondana nocwaningo ngamagciwane abangelwa ubhubhane, kanye nezinto ezibalulekile kanye nabadlali abakha izindawo zokuvikela ukuphepha ezanda kakhulu lapho amagciwane ayingozi ekhona igcinwe futhi yaguqulwa ukuze ibenze babulale kakhulu.

Ingabe ucwaningo lokuthola umsebenzi lufanele ingozi?

Kukhona okuphawulekayo ubufakazi ukuthi amalabhorethri okuphepha okuvikela ukuphepha kokuphila abe nokuningi izingozi, ukwephulwa, Futhi ukwehluleka kokuqukethwe, nokuthi izinzuzo ezingaba khona zocwaningo lokuthola umsebenzi may akufanelekile the izingozi kokubangela izifo ezingaba khona.

Ucwaningo lwe-GOF lokukhathazeka lushintsha futhi luhlole amagciwane ayingozi njenge-Ebola, igciwane lesifo somkhuhlane i-H1N1, kanye nama-coronaviruses ahlobene no-SARS ngaphansi kwerubrikhi yokwenziwa kwezinyathelo zokulwa nezokwelapha (njengemithi yokugoma). Ngenxa yalokho, inesithakazelo hhayi kuphela ku- umkhakha we-biotechnology kanye nowokwenza imithi kepha futhi ukuze umkhakha we-biodefense, ephathelene nokusetshenziswa okungenzeka kocwaningo lwe-GOF ngezenzo ze-biowarfare.

Ucwaningo lwe-GOF ngamagciwane abulalayo yi- Staff umphakathi impilo. Imibiko kokuvuza ngengozi nokwephulwa kokungavikeleki ezindaweni zokucwaninga ze-GOF akuvamile. Ngemuva kokuthi iqembu elivelele lama-virologists lishicilele okuphuthumayo isitatimende sokuvumelana ngoJulayi 14, 2014 ecela ukuthi kumiswe ucwaningo lwe-GOF lokukhathazeka, uhulumeni wase-US ngaphansi kokuphatha kukaMongameli uBarack Obama wabeka umthetho  "Ikhefu lezezimali" ekuhlolweni kwe-GOF okubandakanya amagciwane ayingozi, kufaka phakathi ama-coronaviruses namagciwane omkhuhlane.

Ukuphumula kwemali kahulumeni ocwaningweni lokukhathazeka nge-GOF kwasuswa ngo-2017 ngemuva kwesikhathi lapho uhulumeni wase-US enza khona uchungechunge lwezingxoxo ukuhlola i- izinzuzo nezingozi kuhlotshaniswa nezifundo ezibandakanya ucwaningo lwe-GOF lokukhathazeka.

Ifuna ukwenza izinto obala

Sikhathazekile ngokuthi imininingwane ebaluleke kakhulu kunqubomgomo yezempilo yomphakathi mayelana nemvelaphi ye-SARS-CoV-2, kanye nezingozi zamalabhorethri okuphepha kanye nocwaningo lomsebenzi, kungafihlwa kumanethiwekhi e-biodefense wezinsiza zokuphepha zikazwelonke ze-United Amazwe, iChina, nakwezinye izindawo.

Sizozama ukukhanyisa ngalezi zindaba ngokusebenzisa izicelo zamarekhodi womphakathi. Mhlawumbe sizophumelela. Singahluleka kalula. Sizobika noma yini ewusizo esingayithola.

USainath Suryanarayanan, PhD, ungusosayensi wabasebenzi e-US Right to Know futhi ungumbhali ngokubambisana wale ncwadi, “Izinyosi Ezinyamalalayo: Isayensi, Ezombusazwe kanye ne-Honeybee Health”(Rutgers University Press, 2017).