Olunye ucwaningo lwe-Roundup luthola izixhumanisi ezingaba nezinkinga zempilo yabantu

Phrinta imeyili Ungahlukıselana Ephathwayo

(Kubuyekezwe uFebhuwari 17, kungeza ukugxekwa kokufunda)

A iphepha elisha lesayensi Ukuhlola imithelela yezempilo engaba khona ye-Roundup herbicides kutholakale ukuxhumana phakathi kokuchayeka kumakhemikhali okubulala ukhula i-glyphosate nokwanda kohlobo lwe-amino acid olwaziwa njengengozi yesifo senhliziyo.

Abaphenyi benza izinqumo zabo ngemuva kokudalula amagundane akhulelwe kanye namazinyane abo asanda kuzalwa ku-glyphosate ne-Roundup ngamanzi okuphuza. Bathe babheke ngqo imiphumela ye-glyphosate-based herbicides (GBH) kuma-metabolites we-urinary nokuxhumana ne-gut microbiome ezilwaneni.

Abaphenyi bathi bathole ukwanda okukhulu kwe-amino acid ebizwa nge-homocysteine ​​emidlwane yamaduna evezwe ku-glyphosate ne-Roundup.

"Ucwaningo lwethu lunikeza ubufakazi bokuqala bokuthi ukuvezwa kwe-GBH esetshenziswa kakhulu, kumthamo wokuvezwa komuntu owamukelekayo njengamanje, uyakwazi ukuguqula imetabolites yomchamo kubo bobabili abantu abadala bamagundane namazinyane," kusho abaphenyi.

Leli phepha elinesihloko esithi “Ukuvezwa komthamo ophansi wemithi yokubulala ukhula eglyphosate kuphazamisa i-metabolism yomchamo nokusebenzisana kwayo ne-gut microbiota,” kubhalwe ngabaphenyi abahlanu abasebenzisana ne-Icahn School of Medicine eNtabeni iSinayi eNew York kanti abane baphuma eRamazzini Institute eBologna, e-Italy. Ishicilelwe kumagazini iScientific Reports ngoFebhuwari 5.

Ababhali bavumile ukulinganiselwa okuningi esifundweni sabo, kufaka phakathi usayizi omncane wesampula, kepha bathi umsebenzi wabo ukhombisile ukuthi "ukutholakala komthamo ophansi wokukhulelwa kanye nobuncane be-glyphosate noma i-Roundup kushintshe kakhulu ama-biomarker amaningi womchamo, emadamini nasenzalweni."

Lolu cwaningo lungolokuqala ngoshintsho lwe-metabolomic ye-urinary olwenziwe ngama-herbicides asuselwa ku-glyphosate emithamo njengamanje ebhekwa njengephephile kubantu, kusho abacwaningi.

Leli phepha lilandela ukushicilelwa ngenyanga edlule ka isifundo emaphephandabeni Impilo Yemvelo ethola i-glyphosate kanye nomkhiqizo we-Roundup kungashintsha ukwakheka kwe-gut microbiome ngezindlela ezingaxhunyaniswa nemiphumela emibi yezempilo. Ososayensi abavela eRamazzini Institute nabo babambe iqhaza kulolo cwaningo.

URobin Mesnage, ongomunye wababhali bephepha elashicilelwa ngenyanga edlule ku-Environmental Health Perspectives, wakuphikisa ukuba semthethweni kwephepha elisha. Uthe ukuhlaziywa kwedatha kukhombisa umehluko otholakele phakathi kwezilwane ezivezwe ku-glyphosate nalezo ezingadalulwanga - izilwane ezilawulayo - nazo bezingatholakala ngokufanayo ngemininingwane ekhiqizwe ngokungahleliwe.

“Sekukonke, ukuhlaziywa kwedatha akusekeli isiphetho sokuthi i-glyphosate iphazamisa i-metabolism yomchamo kanye ne-gut microbiota yezilwane eziveziwe,” kusho uMesnage. "Lolu cwaningo luzoqhubeka nokudida kancane impikiswano ngobuthi be-glyphosate."

Izifundo ezimbalwa zakamuva ku-glyphosate naku-Roundup bathole ukukhathazeka okuningi.

I-Bayer, eyathola ifa lomkhiqizo we-herbicide wase-Monsanto's glyphosate kanye nephothifoliyo yezimbewu ezakhiwe ngezofuzo ngesikhathi ithenga inkampani ku-2018, igcizelela ukuthi inqwaba yezifundo zesayensi emashumini eminyaka iqinisekisa ukuthi i-glyphosate ayibangeli umdlavuza. Isikhungo Sokuvikelwa Kwezemvelo e-US kanye nezinye izinhlaka eziningi ezilawula umhlaba nazo azibheki imikhiqizo ye-glyphosate njenge-carcinogenic.

Kepha i-World Health Organisation's International Agency for Research on Cancer ngonyaka ka-2015 yathi ukubuyekezwa kocwaningo lwesayensi kutholakale ubufakazi obanele bokuthi i-glyphosate iyi-carcinogen yabantu.

IBayer ilahlekelwe yizilingo ezintathu kwezintathu ezilethwe abantu abasola umdlavuza wabo ngokuvezwa yimithi yokubulala ukhula kaMonsanto, kanti iBayer ngonyaka odlule ithe izokhokha cishe amaRandi ayizigidi eziyizinkulungwane eziyi-11 ukukhokha izimangalo ezifanayo ezingaphezu kwezingu-100,000 XNUMX.