Olunye uphononongo lweRoundup lufumana amakhonkco kwiingxaki ezinokubakho zempilo yabantu

ushicilelo Imeyli isabelo Ukufuna

(Ukuhlaziywa ngoFebruwari 17, kongeza ukugxeka isifundo)

A iphepha elitsha lezesayensi Ukuvavanya iimpembelelo ezinokubakho kwezempilo zeRoundup herbicides kufumanise unxibelelwano phakathi kokuchasana nokhula olubulala ikhemikhali glyphosate kunye nokonyuka kohlobo lwe-amino acid eyaziwa ngokuba ngumngcipheko wesifo sentliziyo.

Abaphandi benza izigqibo zabo emva kokubhengeza iigundane ezikhulelweyo kunye neentsana zabo ezisandul 'ukuzalwa kwi-glyphosate kunye neRoundup ngamanzi okusela. Bathe bajonge ngokukodwa kwiziphumo ze-glyphosate-based herbicides (GBH) kwiimetabolites zomchamo kunye nokunxibelelana ne-gut microbiome kwizilwanyana.

Abaphandi bathi bafumene ukonyuka okubonakalayo kwe-amino acid ebizwa ngokuba yi-homocysteine ​​kwiintsana zamaduna ezivezwe kwi-glyphosate nakwiRoundup.

"Uphononongo lwethu lubonelela ngobungqina bokuqala bokuba ukubhencwa kwi-GBH esetyenziswa ngokuxhaphakileyo, kumthamo wokubonisa ukubonwa kwabantu okwamkelekileyo okwangoku, kunakho ukuguqula umchamo kwimetabolites kuzo zombini iirati zabantu abadala kunye namantshontsho," utshilo umphandi.

Eli phepha linesihloko esithi “Ukuvezwa kwethamo elisezantsi lokutshabalalisa ukhula lwe-glyphosate-based herbicides kuphazamisa i-metabolism yomchamo kunye nokunxibelelana kwayo ne-gut microbiota,” libhalwe ngabaphandi abahlanu abasebenzisana ne-Icahn School of Medicine kwiNtaba yeSinayi eNew York kunye nezine ezivela eRamazzini Institute eBologna, e-Itali. Yapapashwa kwijenali yeeNgxelo zezeNzululwazi ngoFebruwari 5.

Ababhali bavumile uninzi lwezithintelo kufundo lwabo, kubandakanya nesampulu encinci, kodwa bathi umsebenzi wabo ubonakalisile ukuba "ukubonakaliswa kwethamo eliphantsi kunye nobomi obuncinci kwi-glyphosate okanye iRoundup kutshintshe kakhulu umchamo kwi-biomarker yomchamo, emadamini nakwinzala."

Uphononongo lolokuqala kwiinguqu kwimichamo ye-metabolism ye-urinary eyenziwe yi-glyphosate-based herbicides kwiidosi ekujongwa ukuba zikhuselekile ebantwini, abaphandi bathi.

Eli phepha lilandela ukupapashwa kwinyanga ephelileyo isifundo kwiphephancwadi Imiba yezeMpilo efumene i-glyphosate kunye nemveliso ye-Roundup inokutshintsha ukwakheka kwe-gut microbiome ngeendlela ezinokuthi zinxulunyaniswe neziphumo ezibi zempilo. Inzululwazi ezivela eRamazzini Institute nazo zazibandakanyekile kolo phando.

URobin Mesnage, ongomnye wababhali bephepha elipapashwe kwinyanga ephelileyo kwiiNkqubo zeMpilo yezeNdalo, uthathe umba ngokunyaniseka kwephepha elitsha. Uthe uhlalutyo lwedatha lubonisa iyantlukwano efunyenwe phakathi kwezilwanyana ezivezwe kwi-glyphosate kunye nezo zingatyhilelwanga- izilwanyana ezilawulayo- zinokufunyanwa ngokufanayo nedatha eveliswe ngokungacwangciswanga.

"Ngokubanzi, uhlalutyo lwedatha alusixhasi isigqibo sokuba i-glyphosate iphazamisa umchamo kwimetabolome kunye ne-gut microbiota yezilwanyana eziveziweyo," utshilo uMesnage. "Olu phononongo luya kuphinda luqhubeke ludida nje ingxoxo malunga nobutyhefu be-glyphosate."

Izifundo ezininzi zamva nje kwi-glyphosate kunye ne-Roundup bafumene uluhlu lweenkxalabo.

I-Bayer, eyazuza njenge-Monsanto's glyphosate-based herbicide brand kunye ne-glyphosate-tolerant portal seeded portfolio yayo xa yayithenga inkampani kwi-2018, igcina ukuba ubuninzi besifundo senzululwazi kumashumi eminyaka buqinisekisa ukuba i-glyphosate ayibangeli mhlaza. I-Arhente yokuKhuselwa kokusiNgqongileyo e-US kunye neminye imibutho emininzi yamazwe aphesheya nayo ayithathi njengemveliso ye-glyphosate njenge-carcinogenic.

Kodwa i-Arhente yeHlabathi yezeMpilo yoPhando ngomhlaza kwi-2015 yathi uphononongo lophando lwenzululwazi lufumene ubungqina obaneleyo bokuthi i-glyphosate yinto enokubangela i-carcinogen yabantu.

I-Bayer ilahlekelwe zizilingo ezintathu kwezintathu eziziswe ngabantu abagxeka i-cancer yabo ekuvezeni i-Monsanto's herbicides, kwaye i-Bayer kunyaka ophelileyo ithe izakuhlawula i-11 yezigidigidi zeedola ukuhlawula ngaphezulu kwe-100,000 amabango afanayo.

 

 

Isifundo esitsha sivavanya ifuthe le-Roundup herbicide kwiinyosi zobusi

ushicilelo Imeyli isabelo Ukufuna

Iqela labaphandi baseTshayina lifumene ubungqina bokuba iimveliso zeherbicide ezisekwe kwintengiso ye-glyphosate ziyingozi kwiinyosi zobusi okanye ngaphantsi kwezingqinisiso ezicetyiswayo.

Kwiphepha elipapashwe kwi Ijenali ye-intanethi Iingxelo zeSayensi, Abaphandi abazimanya ne-Chinese Academy of Agricultural Sciences eBeijing kunye ne-Chinese Bureau of Landscape and Forestry, bathi bafumene uluhlu lweempembelelo ezingalunganga kwiinyosi zobusi xa beveza iinyosi kwi-Roundup - a glyphosateImveliso esekwe kuthengiswa ngumnini weMonsanto uBayer AG.

Inkumbulo yeenyosi zeenyosi "yayonakele kakhulu emva kokuvezwa yiRoundup" iphakamisa ukuba ukubonakaliswa okungapheliyo kweenyosi kumachiza okubulala ukhula "kunokuba nefuthe elibi ekufuneni nasekuqokeleleni izixhobo kunye nokulungelelaniswa kwemisebenzi yokutya" ziinyosi, abaphandi bathi .

Kananjalo, "amandla okunyuka kweenyosi zeenyosi anciphile kakhulu emva konyango kunye noxinzelelo lweRoundup," bafumanisa abaphandi.

Abaphandi bathi sikhona isidingo “senkqubo yokutshiza isilumkiso sokutshabalalisa ukhula kwangethuba” kwiindawo ezisemaphandleni e-China kuba abagcini nyosi kulezo ndawo “bahlala bengaziswanga phambi kokuba kutshizwe iherbicides” kwaye “neziganeko zetyhefu rhoqo yeenyosi zobusi” zenzeka.

Ukuveliswa kwezityalo ezininzi ezibalulekileyo zokutya kuxhomekeke kwiinyosi zobusi kunye neenyosi zasendle ukuze kufuduswe umungu, kwaye kuphawulwe ukwehla kubemi beenyosi baphakamise iinkxalabo kwihlabathi liphela malunga nokhuseleko lokutya.

Iphepha eliphuma kwiYunivesithi yaseRutgers ipapashwe kwihlobo elidlulileyo ilumkise ngelithi "isivuno sama-apile, iitsheri kunye namaqunube kulo lonke elaseMelika sincitshiswa kukuswela kwezidlulisi."

Umcimbi weNyaniso-uNjingalwazi uyala ukuLungisa iimpazamo kwiPhepha elitsha leNzululwazi lokufumana iingxaki ngeGlyphosate

ushicilelo Imeyli isabelo Ukufuna

(Ihlaziyiwe ngoJuni 5 kunye nezimvo ezivela kwiiNgxelo zeNzululwazi)

Ababhali bephepha le- iphepha elisandula kupapashwa Ukuvavanya iimpembelelo zokuvezwa kweyeza elisetyenziswa kakhulu emhlabeni kubhengeze iindaba ezothusayo.

The Iqela elivela eWashington State IYunivesithi ifumanise ukuba inzala yeempuku ezivezwe yikhemikhali glyphosate iphuhlise iprostate, isifo sezintso kunye nesifo se-ovari, ukutyeba kakhulu kunye nokuzalwa okungaqhelekanga. Iziphumo, zapapashwa ngo-Epreli kwiphephancwadi lezenzululwazi Iingxelo zeSayensi, Yongezwe kwingxoxo-mpikiswano yomhlaba malunga nokhuseleko lwe-glyphosate kunye ne-Monsanto's Roundup kunye nezinye izinto ezibulala ukhula ezisekwe kwi-glyphosate.

Kodwa mhlawumbi okumangalisa ngakumbi kunezo ndaba, iqela lophando lathi kwiphepha labo ukuba i-Arhente yeZizwe ngezizwe yoPhando ngomhlaza (IARC), ingcali yenzululwazi yeWorld Health Organisation, "ikurhoxisile" ukufumanisa kwayo ukuba i-glyphosate ngumntu onokwenzeka umhlaza.

Impazamo yenye yamaphepha axelwe kubabhali kwinyanga ephelileyo ekusafuneka ilungisiwe. Kodwa akukho namnye, mhlawumbi, okrelekrele ngakumbi kunaleyo malunga ne-IARC.

IARC ikhuphe iphepha elide Ngo-2015 okugqitywe ngokuhlela i-glyphosate njenge-2A yomntu obangela i-carcinogen. Ukwahlulahlula i-IARC kubangele amawaka amatyala ngokuchasene neMonsanto, umcocisi wexesha elide weRoundup kunye nezinye iiglyphosate herbicides kunye nefuthe kwingxoxo kwihlabathi liphela. Ulwahlulo lwe-IARC luye lwanceda ukukhuthaza amazwe amaninzi aseYurophu ukuba aqale ukushenxisa ukunciphisa okanye ukuvala ukusetyenziswa kwe-glyphosate. Izixeko, izithili zesikolo kunye nabathengisi kulo lonke elaseMelika nabo bayekile ukusebenzisa okanye ukuthengisa iimveliso zeglyphosate. Umnini wase-Monsanto waseJamani uBayer AG uphulukene neepesenti ezingama-40 zexabiso lesabelo sakhe ngenxa yenkxalabo eqhubekayo malunga nemichiza yokutshabalalisa ukhula yeMonsanto's glyphosate.

Kodwa ngokweqela le-WSU, ukwahlulwa-hlulwa kwe-IARC okubangelwe kuko konke kwarhoxiswa ngo-2016. Babhala:

“Ngo-Matshi 2015 i-Arhente yaMazwe ngaMazwe yoPhando ngomhlaza yahlulahlula i-glyphosate njenge-carcinogen yeBanga lesi-2a esekwe kukuxhaphaka kwesibindi kunye nezintso kwizifundo zokutya okungapheliyo. Kungekudala emva koko, le ngxelo yachithwa ngo-2016. "

Ukurhoxiswa kwe-IARC kokufumanisa kuya kuba kubaluleke kakhulu. Ewe kunjalo, iMonsanto kwi-2015 yafuna ukurhoxa kodwa i-IARC iwukhusele umsebenzi wayo, njengoko uninzi lwezazinzulu ezizimeleyo ezivela kumazwe amaninzi. Ngokukodwa, i-IARC ayikaze ikurhoxise ukufunyanwa kwayo kwe-glyphosate njenge-2A enokubangela i-carcinogen.

Ukwahlulahlulwa akukatshintshwa kwaye kusasebenza, utshilo isithethi se-IARC uVeronique Terrasse.

Iqela lophando lase Washington State lalikhokelwa ngu UMichael Skinner, Unjingalwazi weSikolo seWSU seSayensi yezebhayoloji. Kubonakala ngathi impazamo iya kuba lula ukuyilungisa. Kodwa xa kuqhakamshelaniswa malunga nale mpazamo, uSkinner wathi wayengenanjongo yokulungisa ingxelo kuba akukho mfuneko yolungiso. Uye wathi uxelele oososayensi abaye baphakamisa umba kunye naye ukuba babhalele umhleli wencwadi.

"Inkcazo yeRetract ibandakanya" Ukuzoba okanye ukubuyela umva okanye ukubuyela "okanye" ukurhoxa okanye ukubuyela umva "okanye" ukuphinda ujonge kwakhona okanye ukubuyela umva ", yiyo loo nto eli gama lisetyenzisiwe kule meko," utshilo uSkinner kwi-imeyile impendulo.

Iingxelo zezeNzululwazi ziyinxalenye yeNdalo, ulindixesha weveki ngeveki ozibiza ngokuba "upapasha olona phando luqwalaselweyo kwezontanga kuwo onke amabakala ezenzululwazi nobuchwephesha…"

Isithethi se IiNgxelo zezeNzululwazi, wathi: "UXa nayiphi na imiba iphakanyisiwe nge Iingxelo zeSayensi ngamaphepha esiwapapasileyo, siwaphanda ngononophelo kwaye sizakuthatha amanyathelo apho kufanelekileyo.

Ucacisile lo nto Iingxelo zeSayensi Ijenali evulekileyo yokufikelela kwi-Intanethi "kusapho loPhando lweNdalo lwejenali" kodwa ngokuzimeleyo kuhlelwa ngokuzimeleyo kweNdalo.

Izazinzulu zangaphandle ezininzi zichonge ezinye iimpazamo eziyinyani ephepheni, kwaye zathi zisongela ukujongela phantsi ukuthembeka kweziphumo zizonke.

"Oku kufanele ukuba kuthathwe ngokujonga koontanga," utshilo UChuck Benbrook, Ingcali yezoqoqosho kwezolimo kunye nengcali ye-glyphosate ethi uphando lwayo lwenzululwazi lukhankanywe ngokungalunganga liqela leSkinner ephepheni labo. UBenbrook uqhakamshelene no-Skinner ngo-Epreli kwangoko emva kokuba iphepha lipapashiwe libeka iimpazamo ezininzi ezifuna ukulungiswa. UBenbrook uqaphele ukuba zonke iingxaki azaziyo zazikwiphepha kwaye zazingenanto yakwenza nezigqibo zesayensi.

“Kutheni engakhange azilungise ngokukhawuleza iimpazamo eziyinyani… kunzima ukuyiqonda,” utshilo uBenbrook.

Phakathi kwezinye iimpazamo eziyinyani:

* Eli phepha lathi i-glyphosate ibangela phantse iipesenti ezingama-72 zokusetyenziswa kwezibulali zinambuzane, icaphula uphando lukaBenbrook. Uphando lukaBenbrook aluthethi loo nto, kodwa ithi iipesenti ezingama-72 zeglyphosate efafazwe kwilizwe jikelele sele isetyenzisiwe kule minyaka ilishumi idlulileyo.

* Iphepha leSkinner lithi udidi lwe-IARC lwe-glyphosate lwalusekwe kukuxhaphaka kwesibindi kunye nezintso kwizifundo zokutya okungapheliyo. Ngapha koko, ulwahlulo lwe-IARC, njengoko kuchaziwe kwiphepha le-IARC, lucacisa ukuba olu luhlu lwalusekwe kwidatha evela kwizifundo zezilwanyana, kwizifundo ze-epidemiology, kunye "nobungqina obunamandla" beendlela zokusebenza kwe-genotoxic.

* Kananjalo, iphepha lakhankanya kumbhalo osemazantsi iphepha elaphikisana nokufunyanwa kwe-IARC ye-glyphosate njenge-carcinogen enokwenzeka ukuba wabhencwa phantse iminyaka emibini eyadlulayo njengomsebenzi obhaliweyo obhaliweyo weenzululwazi zeMonsanto. Iphepha likaSkinner alikhange likuqaphele oko kweli phepha, enesihloko esithi "Ukuhlolwa kwePhaneli yeNgcali yeGenotoxicity: ubunzima bokuvavanywa kobungqina be-genotoxicity ye-glyphosate, i-glyphosate-based formulations, kunye ne-aminomethylphosphonic acid," yayiyingxaki ngenxa yokungabikho kokuchazwa kokubandakanyeka kukaMonsanto kangangokuba iphephancwadi elalipapasha- Ukuphononongwa ngokuPhambili kwiToxicology -Ukhuphe i “Ukubonakalisa inkxalabo"Kunye ingxelo yokulungisa.

Uphando lukaSkinner luxhaswe sisibonelelo esivela kwiJohn Templeton Foundation. Yena noogxa bakhe baveze iigundane ezikhulelweyo kwi-glyphosate phakathi kweentsuku zabo ezisibhozo kunye ne-14th zokukhulelwa. Idosi, abathi sisiqingatha semali ekulindeleke ukuba singabonisi ziphumo zibi, ayivelisanga miphumo mibi kubazali okanye kwisizukulwana sokuqala senzala. Kodwa abaphandi babone ukwanda okumangalisayo "kwezifo ezininzi ezichaphazela isizukulwana sesibini nesesithathu," ngokuka ukukhululwa kweendaba ukukhuthaza isifundo.

Isifundo sifumene uninzi lwengqwalaselo. Zininzi iindawo zeendaba ezixeliweyo kolu phando, becaphula u-Skinner. I-Bayer AG, inkampani yaseJamani eyathenga iMonsanto kunyaka ophelileyo, ithe isifundo sikaSkinner asithembekanga. Kodwa ulusu Ukhusele ukuchaneka kwesifundo, ecaphula inyani yokuba iphinde yajongwa kwakhona kwaye yapapashwa kwijenali eyamkelweyo yesayensi.

(Inqaku lokuqala lavela nge EcoWeb.)

UCarey Gillam yintatheli kunye nombhali, kunye nomphandi onomdla woluntu Ilungelo lase-US lokwazi, iqela lophando lokutya elingenzi nzuzo. Mlandele kuTwitter ku @iqosweb.