Ukuphishekela inyaniso kunye nokubonakala kwimpilo yoluntu

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ushicilelo Imeyli isabelo Ukufuna

Ilungelo lase-US lokwazi ukwandisa umsebenzi walo wophando ukuya kweminye imicimbi yezempilo yoluntu engxamisekileyo, kubandakanya imvelaphi yenoveli ye-coronavirus SARS-CoV-2, ebangela isifo i-COVID-19. Singo Ukufuna iimpendulo kwimibuzo esisiseko malunga nokuba, phi kwaye kutheni le ntsholongwane iqale yabosulela abantu, kunye nolwazi malunga nokuvuza kunye nokunye ukwenzakala kwiilebhu zokutya kunye nemingcipheko yophando lomsebenzi, ejolise ekwandiseni ukubulala okanye ukosuleleka kwezifo ezosulelayo. Asazi okwangoku ukuba olu phando luza kutyhila ntoni, kodwa sikholelwa ekubeni lubalulekile ekukhuseleni impilo yoluntu ukutyhalela elubala. Ungaxhasa umsebenzi wethu ngokunikela apha.

Kule bhulogi sithumela amaxwebhu kunye nolunye uhlaziyo kuphando lwethu lwe-biohazards, olukhokelwa ngu USainath Suryanarayanan, KwiF.D. Jonga eyethu Uluhlu lokufunda kwesi sihloko.

Februwari 17, 2021

Izazinzulu zaseTshayina zazifuna ukutshintsha igama le-coronavirus ebulalayo ukuyisusa e-China

Kwiintsuku zokuqala zobhubhane we-COVID-19, iqela lezazinzulu elidibene norhulumente wase-China lazama ukumisa kude i-coronavirus e-China ngokuphembelela ukubizwa kwayo ngokusemthethweni. Ukuqinisekisa ukuba intsholongwane yafunyanwa okokuqala eWuhan, China, izazinzulu zathi boyika ukuba intsholongwane izakubizwa ngokuba yi "Wuhan coronavirus" okanye "Wuhan pneumonia," ii-imeyile ezifunyenweyo ngu-US ilungelo lokwazi umboniso.

Ii-imeyile zityhila kwangaphambili kwimfazwe yolwazi eqhutywa ngurhulumente wase-China ukuyila ibali malunga nemvelaphi yenoveli coronavirus.

Ukuthiwa kwale ntsholongwane "yinto ebaluleke kakhulu kubantu baseTshayina" kunye nezalathiso zentsholongwane ekhankanya uWuhan "ukubekwa amabala kunye nokuthuka" abahlali baseWuhan, imbalelwano esuka kuFebruwari 2020 ithi.

Ngokukodwa izazinzulu zaseTshayina zathi igama lobuchwephesha elinikezelwe intsholongwane- "isifo esiqatha sokuphefumla isifo coronavirus 2 (SARS-CoV-2)" - kwakungekho nje "kunzima ukuyikhumbula okanye ukuyibona" ​​kodwa "yayilahlekisa ngokwenyani" kuba yayihambelana intsholongwane entsha kuqhambuko lukaSARS-CoV lowama-2003 olwavela eChina.

Le ntsholongwane yathiywa liQela loFundo lweCoronavirus (CSG) leKomiti yeHlabathi yeRhafu yeTholongwane (ICTV).

Iziko lase-Wuhan leVirology sisazinzulu esiphezulu uZhengli Shi, okhokele ukubizwa kwakhona umzamo, echazwe nge-imeyile kwiYunivesithi yaseNorth Carolina i-virologist uRalph Baric, "ingxoxo eyoyikisayo phakathi kweentsholongwane zaseTshayina" ngegama leSARS-CoV-2.

UDeyin Guo, owayesakuba ngumphathi weSikolo seYunivesithi yaseWuhan seNzululwazi yezoBomi kunye nombhali-mbhali wesindululo sokutshintsha igama, wabhala kumalungu e-CSG athe asilela ukubonisana nesigqibo sawo sokuqamba amagama “neengcali zentsholongwane kubandakanya nezokuqala ukufumanisa [Sic] yentsholongwane kunye nabachazi bokuqala besifo ”abasuka kwilizwe lase China.

“Akufanelekanga ukusebenzisa igama lentsholongwane elisekwe kwisifo elinye (njenge-SARS-CoV) ukubiza zonke ezinye iintsholongwane zendalo ezikulohlobo olunye kodwa ezineempawu ezahlukileyo,” ubhale watsho kwimbalelwano ethunyelwe yena ezinye izazinzulu ezintlanu zamaTshayina.

Iqela licebise elinye igama- “Ukudluliselwa kwe-coronavirus ebuhlungu yokuphefumla (i-TARS-CoV). Olunye ukhetho, bathi, inokuba yi- "Human acute coronavirus (HARS-CoV)."

Umsonto we-imeyile ochaza utshintsho lwegama obhaliweyo wacelwa uSihlalo we-CSG uJohn Ziebuhr.

Imbalelwano ibonisa ukuba uZiebuhr akavumelani nengcinga yeqela laseTshayina. Uphendule ngelithi “igama elithi SARS-CoV-2 linxibelelanisa le ntsholongwane nezinye iintsholongwane (ezibizwa ngokuba zii-SARS-CoVs okanye ii-SARSr-CoVs) koluhlobo kubandakanya nentsholongwane yohlobo lwesi sifo endaweni yesifo esakha sakhuthaza ukubizwa kwale prototype intsholongwane phantse kwiminyaka engama-20 eyadlulayo. Isimamva -2 sisetyenziswa njengesazisi esikhethekileyo kwaye sibonisa ukuba i-SARS-Co V-2 iseyeNYE (kodwa inxulumene ngokusondeleyo) nentsholongwane kolu hlobo. ”

Imithombo yeendaba kaRhulumente yase China CGTN umbiko omnye umzamo Nge-Matshi 2020 ngama-virologist aseTshayina abiza i-SARS-CoV-2 njenge-coronavirus yabantu i-2019 (i-HCoV-19), engakhange idlule kwi-CSG.

Ukuthiya intsholongwane ebangela ubhubhane-uxanduva lwe-World Health Organisation (i-WHO) -kuhlala kuyinto ityala lezopolitiko ukuzivocavoca kuluhlu lwetaxonomic.

Ukuqhambuka kwangaphambili kwefayile ye- Umkhuhlane weH5N1 intsholongwane eyavela e-China, urhulumente wase-China watyhala i-WHO ukuba yenze i-nomenclature engazukubopha amagama e-virus kwiimbali okanye kwiindawo ezivela kuyo.

Ukuze ufumane inkcazelo engakumbi

Iimeyile zeYunivesithi yaseNorth Carolina uNjingalwazi uRalph Baric, ethi i-US Right to Know ifunyenwe ngesicelo seerekhodi zoluntu, inokufumaneka apha: I-baric imeyile ibatch # 2: iYunivesithi yaseNorth Carolina (Iphepha le-332)

Ilungelo lase-US lokwazi ukuthumela amaxwebhu avela kwizicelo zethu zeerekhodi zoluntu zophando lwethu lwee-biohazards. Bona: Amaxwebhu e-FOI kwimvelaphi ye-SARS-CoV-2, iingozi zokufumana umsebenzi kunye neelebhu zokutya.

Iphepha elingasemva kuphando lwase-US lweLungelo lokwazi ngemvelaphi ye-SARS-CoV-2.

Februwari 15, 2021

I-imeyile ibonisa ukuba izazinzulu zixoxa ngokufihla ukubandakanyeka kwabo kwileta ephambili yejenali kwimvelaphi yeCovid

UMongameli we-EcoHealth Alliance uPeter Daszak, intloko yombutho obandakanyekayo kuphando olusebenzisa i-coronaviruses yemfuza, uxoxe ngokufihla indima yakhe ingxelo epapashwe kunyaka ophelileyo ngo Lancet egweba njenge “theori zelenqe” ixhala lokuba intsholongwane i-COVID-19 inokuba ivele kwilebhu yophando, ii-imeyile ezifunyenwe yi-US Right to Know show.

Isiteyitimenti seLancet, esisayinwe ngoososayensi abaziwayo abangama-27, sibe nefuthe ekunciphiseni urhano kwizazinzulu ezithile ukuba i-COVID-19 inokuba nobudlelwane ne-Wuhan Institute of Virology yase China, enophando olunxulumene ne-EcoHealth Alliance.

UDaszak wayila ingxelo kwaye wayisasaza kwezinye izazinzulu ukuba zisayine. Kodwa i email kutyhila ukuba uDaszak kunye nabanye oososayensi abasebenzisana ne-EcoHealth bacinga ukuba akufuneki basayine ingxelo ukuze bafihle ukubandakanyeka kwabo kuyo. Ukushiya amagama abo kwingxelo kuya kuyinika "umgama othile kuthi kwaye ke ayisebenzi ngendlela ephikisayo," ubhale watsho uDaszak.

UDaszak uqaphele ukuba "angayithumela ajikeleze" kwezinye izazinzulu ukuba zisayine. "Emva koko siza kuyibeka ngendlela engadibanisiyo nentsebenziswano yethu ukuze sonyuse ilizwi elizimeleyo," ubhale watsho.

Oososayensi ababini u-Daszak ubhalele malunga nesidingo sokwenza iphepha libonakale lizimeleyo kwi-EcoHealth, ziingcali ze-coronavirus uRalph Baric noLinfa Wang.

Kwiimeyile, uBaric wavumelana nengcebiso kaDaszak yokuba angatyikityi Lancet Isiteyitimenti, sibhala "Ngaphandle koko kubonakala ngathi kukuzenzela, kwaye siphulukana nefuthe."

UDaszak ekugqibeleni wayisayina ngokwakhe ingxelo, kodwa akazange achongwe njengombhali okanye umququzeleli womzamo.

Ii-imeyile ziyinxalenye yamaxwebhu afunyenwe yi-US Right to Know ebonisa ukuba iDaszak ibisebenza ukusukela ekuqaleni konyaka ophelileyo ukujongela phantsi ingcinga ukuba i-SARS-CoV-2 inokuba ivuza kwi IZiko laseWuhan.

Ukuqhambuka kokuqala kwe-COVID-19 kwakukwisixeko saseWuhan.

Ilungelo lase-US lokwazi ngaphambili uxele ukuba uDaszak wayila ingxelo Lancet, kwaye wayilungiselela ukuba "Ingabonakali njengevela kumbutho omnye okanye umntu omnye" kodwa kunokuba kubonwe njenge “Ileta nje evela kwizazinzulu eziphambili”.

Umanyano lwe-EcoHealth yinto engenzi nzuzo ese-New York efumene izigidi zeedola kwinkxaso mali yomhlawuli werhafu waseMelika ekusebenziseni i-coronaviruses yemfuza, kubandakanya nezazinzulu kwiZiko laseWuhan.

Ngokukodwa, iDaszak ivele njengoyena mntu uphambili kuphando olusemthethweni ngemvelaphi ye-SARS-CoV-2. Ulilungu le iWorld Health OrganizationIqela leengcali ezilanda imvelaphi yenoveli, kunye Lancet IKhomishini ye-COVID 19.

Jonga ingxelo yethu yangaphambili kwesi sihloko: 

Bhalisela iincwadana zethu zasimahla ukufumana uhlaziyo rhoqo kuphando lwethu lwee-biohazards. 

January 21, 2021

Amaxwebhu eYunivesithi yaseColorado State kwi-bat pathogen yophando

Esi sithuba sichaza amaxwebhu oonjingalwazi baseColorado State University (CSU) uRebekah Kading kunye noTony Schountz, nelungelo lase-US lokuLwazi elifunyenwe kwisicelo seerekhodi zoluntu. UKading kunye no-Schountz zii-virologists ezifunda izifo ezinxulumene nelulwane kwiindawo ezishushu kwihlabathi liphela. Basebenzisana ne-EcoHealth Alliance, iSebe lezoKhuselo lase-US (i-DoD) kunye ne-Arhente yeeProjekhthi zoPhando oluPhambili (i-DARPA), uphando lwezomkhosi wase-US nengalo yophuhliso.

La maxwebhu abonisa umbono kwi ezintsonkothileyo zemikhosi yezenzululwazi abafunda ngendlela yokuthintela ukuvela kwezinto ezinokubangela ubhubhane kumalulwane. La maxwebhu aphakamisa imibuzo malunga nomngcipheko wokosuleleka, umzekelo, ukuthunyelwa kwamalulwane kunye neempuku ezisulelwe zizifo eziyingozi. Ziqulathe ezinye izinto eziphawuleka, kubandakanya:

  1. NgoFebruwari 2017, abaququzeleli be-DoD yeNkqubo yeNtsebenzo ye-Biological Engagement ye-Arhente yokuNcitshiswa kweNgozi yoKhuselo umemezele umfelandawonye omtsha welizwe jikelele "ukwakha nokunyusa amandla elizwe kunye nemimandla ukuvelisa ukuqonda okuphuculweyo kwamalulwane kunye nendalo kwindawo yokujongana nezifo ezikhuselayo." Inxulumene noku, ii-imeyile bonisa intsebenziswano phakathi kwe-CSU, i-EcoHealth Alliance kunye namaZiko eSizwe e-Rocky Mountain Laboratories ukwakha indawo yophando ye-bat kwi-CSU ukwandisa izifundo zosulelo.
  2. Umdibaniso welizwe lonke weqela uguquke waba liqela elibizwa ngokuba yiBat One Health Network Network (IBOHRN). Ngo-2018, izazinzulu eziphambili ze-BOHRN zazisebenza ne-DARPA kwiprojekthi ebizwa ngokuba yi-PREEMPT. Iirekhodi ze-CSU kwi-PREEMPT bonisa ukuba iRocky Mountain Laboratories, i-CSU kunye ne-Montana State University baphuhlisa izitofu "ezinokuchaphazeleka ezinokuchaphazeleka" ukuze zisasazeke kubemi bamalulwane "ukunqanda ukuvela kunye nokusasazeka" kweentsholongwane ezosulelayo ezivela kumalulwane ziye kubemi babantu. Injongo yabo kukuphuhlisa “izitofu ezizisasaza ngokwazo ” -Esasazeka ngokusasazeka phakathi kwamalulwane-ngethemba lokususa ii-pathogen kwindawo yazo yezilwanyana ngaphambi kokuba kudilike ebantwini. Olu phando luphakamisa xhalaba malunga neziphumo ebezingalindelwanga zokukhulula izinto ezizisasaza ngokwasofuzo, kunye nemingcipheko yendalo yendaleko yabo engaziwayo, ubundlobongela kunye nokusasazeka.
  3. Ukuhambisa amalulwane kunye neempuku ezosulelwe zizifo eziyingozi kudala ukubakho kokungathandeki okungafunekiyo ebantwini. UTony Schountz wabhala kwi-EcoHealth Alliance VP uJonathan Epstein ngo-Matshi 30, 2020: "I-RML [Rocky Mountain Labs] ingenise indawo yokugcina intsholongwane ye-Lassa ngokubazalela ekuthinjweni e-Afrika, emva koko inzala yathunyelwa ngqo kwi-RML. Andazi nokuba amalulwane amahashe angazalwa esekuthinjweni, kodwa leyo ingayindlela yokunciphisa inkxalabo yeCDC. ” Intsholongwane yeLassa Isasazwa ziimpuku ezixhaphakileyo entshona Afrika. Kubangela ukugula kakhulu okubizwa ngokuba yiLassa fever ebantwini, ekhokelela ekuqikelelweni kwabantu abangama-5,000 1 ngonyaka (XNUMX% izinga lokufa).
  4. NgoFebruwari 10, 2020, uMongameli woMbutho we-EcoHealth uPeter Daszak uthumele i-imeyile Ukucela abatyikityo ukuba bayile The Lancet mazwi "Ukugxeka kabukhali iithiyori ezibonisa ukuba i-2019-nCoV ayinayo imvelaphi yendalo." Kule imeyile, uDaszak wabhala: “UGqr. U-Linda Saif, u-Jim Hughes, u-Rita Colwell, u-William Karesh kunye no-Hume Field bayile ingxelo elula yokuxhasa oososayensi, ezempilo yoluntu kunye noochwephesha bezonyango e-China abalwa noku kuqhambuka (kuqhotyoshelweyo), kwaye siyakumema ukuba usijoyine njengabasayini bokuqala. ” Khange akhankanye ukubandakanyeka kwakhe ekuyileni ingxelo.  Ingxelo yethu yangaphambili bonisa loo nto UDaszak wayila ingxelo eyayipapashwe kwi Lancet.
  5. UTony Schountz watshintshisa ii-imeyile kunye ne-Wuhan Institute of Virology (WIV) zezenzululwazi uPeng Zhou, uZhengli Shi kunye noBen Hu. Kwi i-imeyile yomhla we-30 ka-Okthobha u-2018, USchountz wacebisa uZhengli Shi “umanyano olungavumelekanga” phakathi kweLebhu ye-Arthropod ehanjiswa yi-Arthropod ne-Infectious Disease Laboratory ne-WIV, ebandakanya “intsebenziswano kwiiprojekthi ezifanelekileyo (umz., Iiarboviruses kunye ne-bat-borped-virus) kunye noqeqesho lwabafundi.” UZhengli Shi uphendule kakuhle Ingcebiso kaSchountz. Iirekhodi azibonisi ukuba nayiphi na intsebenziswano iqalile.

Ukuze ufumane inkcazelo engakumbi

Ikhonkco kulo lonke ibhetshi yamaxwebhu e-Colorado State University anokufumaneka apha: Iirekhodi ze-CSU

Ilungelo lase-US lokwazi ukuthumela amaxwebhu afunyenwe ngenkululeko yoluntu yokufumana ulwazi (FOI) yezicelo uphando lwethu lweBiohazards Kwiposi yethu: Amaxwebhu e-FOI kwimvelaphi ye-SARS-CoV-2, iingozi zokufumana umsebenzi kunye neelebhu zokutya.

Zikhuseleke kangakanani ii-biolabs e-Colorado State?

Uyilo lwesindululo senkxaso-mali fokanye ukwakhiwa kwebiolab entsha kwiYunivesithi yaseColorado State iphakamisa imibuzo malunga nokhuselo nokhuseleko kwii-biolabs ezikhoyo eFort Collins, eColorado.

Isindululo esiyidrafti sifuna inkxaso-mali kumaZiko ezeMpilo kaZwelonke ukubuyisela iziseko zophuhliso “zokuguga” kwii-CSU's IZiko leVector-Borne Infectious Diseases, eyayibizwa ngokuba yiLebhu yeArthropod kunye neLebhu yezifo eziSulelayo (AIDL). Eli ziko likhulisa izinambuzane kunye neelulwane kulingo lwezifo ezosulelayo kunye nezifo eziyingozi ezinje ngeSARS, iZika, Nipah kunye neHendra virus. Uvavanyo lwe-Live-pathogen apho lwenziwa kwinxalenye ye- I-BSL-3 Izibonelelo, ezizelebhu ezixineneyo emoyeni ezinobuchwephesha obukhethekileyo ukunqanda abaphandi ekufumaneni ukosuleleka kunye nokusasazeka kosulelo.

Ababhali besindululo (uTony Schountz noGreg Ebel be-CSU noJonathan Epstein, usekela-mongameli e-EcoHealth Alliance) babhala bathi, "izakhiwo zethu ezininzi zidlulile kubomi bazo obuluncedo." Bancamathisela imifanekiso yokuqokelela ukungunda kunye nokungunda njengobungqina bendawo "ethoba ngokukhawuleza" indawo "evuzayo xa kunethayo."

Isindululo sikwacacisa ukuba uyilo esele lukhona lwelebhu lufuna iisampulu zamalulwane kunye nezinambuzane ezisulelekileyo ukuba "zihanjiswe zisiwe kwizakhiwo ezahlukeneyo ngaphambi kokuba zisetyenziswe." Ithi ii-autoclaves esele zikhona, ezibulala izinto ezinobungozi, "zihlala zingasebenzi kakuhle kwaye kukho inkxalabo efanelekileyo yokuba ziya kuqhubeka nokwenza njalo."

Kungenzeka ukuba iingxaki zigqithise kuba baxhasa isicelo senkxaso mali. Nantsi inkcazo evela kwisindululo senkxaso mali kunye nemifanekiso.

Isindululo siphakamisa imibuzo eliqela: Ngaba ubomi bomntu busemngciphekweni ovela kwizixhobo ezingalunganga ze-AIDL kunye neziseko zophuhliso? Ngaba oku kungangqinelani kunyusa amathuba okuvuza ngengozi kwezifo eziyingozi? Ngaba akhona amanye amaziko amanyeneyo e-EcoHealth kwihlabathi liphela athotyelwe ngokufanayo kwaye angakhuselekanga? Ngaba iimeko ezifanayo bezingakhuselekanga, umzekelo, i-EcoHealth Alliance exhaswa ngemali yi-Wuhan Institute of Virology? Elo ziko ichongiwe njengomthombo onokubakho Ye-SARS-CoV-2, intsholongwane ebangela iCovid-19.

Iirekhodi zekomiti yezokhuseleko ye-CSU (IBC), efunyenwe ngesicelo seerekhodi zoluntu, kubonakala ngathi iqinisa inkxalabo malunga nokhuseleko lwee-biolabs ze-CSU. Umzekelo, imizuzu yentlanganiso ukusukela ngoMeyi 2020 bonisa ukuba umphandi we-CSU ufumene usulelo lwentsholongwane yeZika kunye neempawu emva kokusebenzisa iingcongconi ezosulelekileyo. I-IBC iqaphele: "Inokuba le yayiyinto yokulunywa yingcongconi engazange ibonwe ngexesha lesiphithiphithi ngenxa yokuvalwa kwe-COVID-19 kunye notshintsho."

Ngelishwa, uphando lwezifo ezosulelayo kwi-SARS-CoV-2 lunokuthi luphakamise umngcipheko wokuphelelwa kukukhuseleka kunye nokungahambi kakuhle kwi-CSU. Imizuzu ye-IBC bonakalisa inkxaso ye "Iinkxalabo eziphakanyisiweyo malunga nenani elikhulu leeprojekthi zophando ezibandakanya i-SARS-CoV-2 ebeke uxinzelelo kwizibonelelo ezifana ne-PPE, indawo yeelebhu, kunye nabasebenzi."

Ukuba ungathanda ukufumana uhlaziyo rhoqo malunga nophando lwethu lwe-biohazards, unako bhalisela iincwadana zethu zeveki apha

January 8, 2021

I-USRTK ibuza i-ODNI ukuba ichaze amaxwebhu malunga neengozi kwiilebhu ezigcina izifo eziyingozi

Ilungelo lase-US lokwazi (USRTK) ubuzile iOfisi yoMlawuli weSebe lezoBuntlola leSizwe (i-ODNI) ukubhengeza amaxwebhu amathathu malunga nokushiyeka kokungabikho kokutya okuvela kwiilebhu ezigcina iintsholongwane eziyingozi.

Isicelo esinyanzelekileyo sokuphononongwa ngokutsha (MDR) siphendula kwii-ODNI sigqibo ukubamba amaxwebhu amathathu ahleliweyo aphendulayo Isicelo soMthetho weNkululeko yoLwazi USRTK ungenisiwe ngoAgasti 2020.

Isicelo se-FOIA "safuna ubukrelekrele obugqityiweyo obuveliswe ukusukela ngoJanuwari 2015 malunga nokukhululwa ngengozi okanye ngabom kweearhente zebhayoloji, ukusilela kokuthintela amanqanaba e-biosafety-level (BSL) -2, BSL-3 okanye BSL-4 kumaziko ophando, kunye nezinye izehlo zokukhathazeka ezinxulumene Ukusetyenziswa kabini kophando lwe-biosafety kwi-BSL-2, BSL-3 okanye BSL-4 kumaziko ophando eCanada, China, Egypt, France, Germany, India, Iran, Israel, Netherlands, Russia, kumazwe angaphambili eSoviet Union, eMzantsi Afrika , ETaiwan, eUnited Kingdom, naseThailand. ”

I-ODNI ithe ekuphenduleni kwayo ukuba ifumene amaxwebhu amathathu, kwaye igqibe kwelokuba "mababanjwe xa bebonke ngokungqinelana nokuxolelwa kwi-FOIA" ngokubhekisele kukhuseleko lwezixhobo ezihleliweyo ngokubhekisele kwiindlela zobuntlola kunye nemithombo yokufaneleka kukhuseleko lwesizwe. I-ODNI ayichazanga okanye ichaze ubume bamaxwebhu amathathu okanye imixholo yawo, ngaphandle kokuba ayephendula kwisicelo seFOIA.

Kwisicelo sayo se-MDR, i-USRTK icele ukuba i-ODNI ikhulule onke amaqhekeza amaxwebhu amathathu.

I-USRTK ikholelwa ekubeni uluntu lunelungelo lokwazi ukuba yeyiphi idatha ekhoyo malunga neengozi, ukuvuza kunye nokunye okungahambi kakuhle kwiilebhu apho kugcinwa khona izifo ezinokubangela ubhubhane kwaye zilungiswe, nokuba ingaba kukho na ukuvuza okunjalo kuyanyanzeliswa kwimvelaphi ye-COVID-19, ebangele ukuba Ukufa kwabantu abangaphezu kwama-360,000 baseMelika.

Ukuze ufumane inkcazelo engakumbi

Ilungelo lase-US lokwazi ukuthumela amaxwebhu avela kwizicelo zethu zeerekhodi zoluntu zophando lwethu lwee-biohazards. Bona: Amaxwebhu e-FOI kwimvelaphi ye-SARS-CoV-2, iingozi zokufumana umsebenzi kunye neelebhu zokutya.

Iphepha elingasemva kuphando lwase-US lweLungelo lokwazi ngemvelaphi ye-SARS-CoV-2.

Disemba 29, 2020

Iidasethi eziguqulweyo ziphakamisa imibuzo ethembekileyo malunga nezifundo eziphambili kwimvelaphi yecoronavirus

Uhlaziyo lwedatha ye-genomic enxulumene nezifundo ezine eziphambili kwimvelaphi ye-coronavirus yongeza eminye imibuzo malunga nokuthembeka kwezi zifundo, ezibonelela ngenkxaso esisiseko ye-hypothesis ukuba i-SARS-CoV-2 ivela kwizilwanyana zasendle. Izifundo, UPeng Zhou et al., Hong Zhou okqhubekayo., Lam kunye al., yaye Xiao okqhubekayo., Ufumanise ii-coronaviruses ezinxulumene ne-SARS-CoV-2 kumalulwane amahashe kunye neepangolins zaseMalayan.

Ababhali bezifundo bafaka idatha yokulandelelana kweDNA ebizwa ngokuba ngokulandelelana kufundwa, ababeyisebenzisela ukudibanisa i-bat- kunye ne-pangolin-coronavirus genomes, kwiZiko leSizwe loLwazi lwe-Biotechnology (NCBI) ngokulandelelana funda indawo yokugcina (SRA). I-NCBI iseke ugcino lwedatha yoluntu ukunceda ukungqinisisa okuzimeleyo kohlalutyo lwe-genomic ngokusekwe kubuchwephesha bokulandelelana okuphezulu.

Ilungelo lase-US lokuFumana amaxwebhu ngokwenziwa kweerekhodi zikarhulumente ukuba bonisa uhlaziyo kwezi zifundo 'i-SRA yedatha yeenyanga emva kokuba zipapashiwe. Olu hlaziyo aluqhelekanga kuba lwenzekile emva kokupapashwa, kwaye ngaphandle kwesizathu, inkcazo okanye ukuqinisekiswa.

Umzekelo, UPeng Zhou et al. kwaye Lam kunye al. bahlaziya idatha yabo ye-SRA ngemihla emibini efanayo. La maxwebhu awachazi ukuba kutheni etshintshe idatha, kuphela ukuba kwenziwe utshintsho oluthile. Xiao okqhubekayo. benze utshintsho oluninzi kwidatha yabo ye-SRA, kubandakanya nokususwa kweedatha ezimbini ngo-Matshi 10, ukongezwa kwedatha entsha ngoJuni 19, ukutshintshwa kwedatha ngoNovemba 8 kwedatha yokuqala eyakhutshwa ngo-Okthobha u-30, kunye nolunye utshintsho lwedatha ngo-Novemba 13- kwiintsuku ezimbini emva koko indalo yongeze "inqaku lenkxalabo" loMhleli malunga nesifundo. Hong Zhou okqhubekayo. awusabelani ngedatha epheleleyo ye-SRA eya kwenza ukuba uqinisekiso luzimele. Ngelixa iijenali zithanda indalo ifuna ababhali ukuba benze yonke idatha "ifumaneke ngokukhawuleza”Ngexesha lokupapashwa, idatha ye-SRA inokukhutshwa emva upapasho; kodwa ayiqhelekanga ukwenza olo tshintsho kwiinyanga emva kokupapashwa.

Olu tshintsho lungaqhelekanga kwidatha ye-SRA alwenzi ngokuzenzekelayo ukuba ezi zifundo zine kunye needatha zazo ezinxulumene nazo zingathembeki. Nangona kunjalo, ukulibaziseka, izithuba kunye notshintsho kwidatha ye-SRA Indibano ezimeleyo kunye nokuqinisekiswa yokulandelelana kwe-genome ngokulandelelana, kwaye yongeza ku imiba kwaye xhalaba malunga le sekile kwezi zifundo zine, ezinje:

  1. Luluphi olona hlaziyo lwasemva kokupapashwa kwedatha ye-SRA? Zazenzelwe ntoni? Ziluchaphazele njani uhlalutyo oluhambelana nolwe-genomic kunye neziphumo?
  2. Ngaba oku kuhlaziywa kwe-SRA kuqinisekiswe ngokuzimeleyo? Ukuba kunjalo, njani? Inkqubo ye- Ukuqinisekiswa kweNCBI kuphela Indlela yokushicilela iSRA BioProject- ngaphaya kolwazi olusisiseko oluthi "igama lomzimba" - kukuba ayinakuphindwa.

Ukuze ufumane inkcazelo engakumbi

The IZiko leLizwe leNkcazelo yeBiotechnology (NCBI) amaxwebhu anokufunyanwa apha: Ii-imeyile zeNCBI (Iphepha le-63)

Ilungelo lase-US lokwazi ukuthumela amaxwebhu avela kwizicelo zethu zeerekhodi zoluntu zophando lwethu lwee-biohazards. Bona: Amaxwebhu e-FOI kwimvelaphi ye-SARS-CoV-2, iingozi zokufumana umsebenzi kunye neelebhu zokutya.

Iphepha elingasemva kuphando lwase-US lweLungelo lokwazi ngemvelaphi ye-SARS-CoV-2.

Disemba 18, 2020

Alukho uphononongo loontanga lwesongezo kwisifundo se-coronavirus semvelaphi?

Ijenali indalo khange kuvavanye ukuthembeka kwamabango abalulekileyo enziwe nge-17 kaNovemba sihlomelo iya ku isifundo kwimvelaphi ye-bat yenoveli coronavirus SARS-CoV-2, imbalelwano ne indalo Abasebenzi bacebisa.

Ngo-Februwari 3, 2020, iZiko laseWuhan leSayensi yeVirology lafumanisa esona salamane sisondeleyo saziwayo seSARS-CoV-2, i-bat coronavirus ebizwa ngokuba yiRaTG13. I-RaTG13 iye yangumbindi kwingcinga yokuba i-SARS-CoV-2 ivela kwizilwanyana zasendle.

Idilesi yezihlomelo engaphendulwanga imiba malunga nemvelaphi yeRaTG13. Ababhali, uZhou et al., Bacacisa ukuba bafumene i-RaTG13 kwi-2012-2013 "kwindawo encinci yokulahla umzuzu kwi-Mojiang County, kwiPhondo lase-Yunnan," apho abasebenzi-mgodini abathandathu beva ubunzima uxinzelelo olukhulu lokuphefumla emva kokuvezwa lilindle, yaye abathathu babhubha. Uphando lwe Iimpawu zabavukuzi abagulayo zinokunika imikhondo ebalulekileyo malunga nemvelaphi ye-SARS-CoV-2. UZhou et al. baxela ukuba abafumananga i-coronaviruses ezinxulumene ne-SARS kwiisampuli ze-serum ezigciniweyo zabasebenzi-mgodini abagulayo, kodwa abawaxhasi amabango abo ngedatha nangeendlela malunga novavanyo lwabo kunye nolawulo lokulinga.

Ukungabikho kwedatha ephambili kwisihlomelo kuye iphakamise eminye imibuzo malunga nokuthembeka kweZhou et al. ukufunda. Nge-27 kaNovemba, i-US Right to Know yabuza indalo imiba malunga namabango esihlomelo, kwaye wacela ukuba indalo papasha yonke idatha exhasayo ethi Zhou et al. inokuba inikezele.

NgoDisemba 2, indalo Intloko yezoNxibelelwano uBex Walton phendula ukuba u-Zhou et al. Isifundo “besichanekile kodwa singacacanga,” kwaye isihlomelo besifanelekile iqonga emva kokupapashwa Ingcaciso. Wongeze wathi: “Malunga nemibuzo yakho, singakuyalela ukuba uye kubabhali bephepha ukufumana iimpendulo, njengoko le mibuzo ayibhekiseli kuphando esilupapashileyo kodwa kolunye uphando olwenziwe ngababhali, apho singenakho ukuphawula ”(ugxininiso lwethu). Ukusukela imibuzo yethu enxulumene nophando oluchazwe kwisihlomelo, i indalo Isiteyitimenti sommeli sicebisa ukuba iZhou et al.isihlomelo asivavanywanga njengophando.

Sibuze Umbuzo olandelayo Nge-2 kaDisemba: “ingaba esi sihlomelo besiphantsi koqwalaselo loontanga kunye / okanye ukonganyelwa kokuhlelwa ngu indalo? ” UNks Walton akazange aphendule ngqo; yena phendula: "Ngokubanzi, abahleli bethu baya kuvavanya izimvo okanye iinkxalabo eziphakanyiswe nathi okokuqala, bebuza ababhali, kwaye befuna iingcebiso kubavavanyi boontanga nakwezinye iingcali zangaphandle ukuba sikubona kufanelekile. Umgaqo-nkqubo wethu wokugcina imfihlo uthetha ukuba asinakho ukugqabaza ngendlela ethile yokuphathwa kwamatyala. ”

ukusukela indalo uthathela ingqalelo isihlomelo njenge iposiuhlaziyo loshicilelo, kwaye ayisixhomekisi eso sithuba sokupapashwa kwezihlomelo kwimigangatho efanayo yokujonga oontanga njengopapasho lwantlandlolo, kubonakala ngathi uZhou et al. isihlomelo asikhange sijongwe kwakhona.

Ababhali uZhengli Shi noPeng Zhou abaphendulanga imibuzo yethu malunga nabo indalo isihlomelo.

Disemba 14, 2020

Ii-imeyile ezintsha zibonisa iingxoxo zesayensi malunga nendlela yokuxoxa ngemvelaphi ye-SARS-CoV-2 

Ii-imeyile ezintsha ezisandula ukufunyanwa zinika amagqabantshintshi ngendlela ingxelo eqinisekileyo ephuculwe ngayo malunga nemvelaphi yendalo yenoveli coronavirus SARS-CoV-2, ngelixa imibuzo ephambili yesayensi ishiyekile. Iingxoxo zangaphakathi kunye nokuyilwa kwangoko kweleta yenzululwazi zibonisa iingcali zixoxa ngezikhewu kulwazi kunye nemibuzo engaphendulwanga malunga nemvelaphi yeelebhu, nanjengoko abanye bebefuna ukuthomalalisa iingcamango “zemiphetho” malunga nokuba kungenzeka ukuba intsholongwane ivela kwilebhu.

Izazinzulu ezinempembelelo kunye neendaba ezininzi ziye zabuchaza ubungqina njengo “eyoyikisayo”Le ntsholongwane yavela kwizilwanyana zasendle, hayi kwelebhu. Nangona kunjalo, unyaka emva kwamatyala okuqala axeliweyo e-SARS-CoV-2 kwisixeko sase-China iWuhan, kuncinci okwaziwayo njani okanye phi intsholongwane yavela. Ukuqonda imvelaphi ye-SARS-CoV-2, ebangela isifo i-COVID-19, kungabalulekile ekuthinteleni ubhubhane olandelayo.

I-imeyile yengcali yecoronavirus UNjingalwazi uRalph Baric - ifunyenwe kwisicelo seerekhodi esidlangalaleni yi-US Right to Know-bonisa incoko phakathi kwabameli be-National Academy of Sciences (NAS), kunye neengcali kukhuseleko lwezinto eziphilayo kunye nezifo ezosulelayo ezivela kwiiyunivesithi zase-US kunye Umanyano lwe-EcoHealth.

Ngomhla kaFebruwari 3, iOfisi yeWhite House yoMgaqo-nkqubo wezeNzululwazi nobuChwepheshe (OSTP) wabuza iZiko lezeMfundo kuZwelonke lezeNzululwazi, ubuNjineli kunye noNyango (NASEM) "ukubiza intlanganiso yeengcali… ukuvavanya ukuba yeyiphi idatha, ulwazi kunye neesampulu ezifunekayo ukujongana nokungaziwa, ukuze kuqondwe imvelaphi yendaleko ye-2019-nCoV, kunye nokuphendula ngokufanelekileyo ukuqhambuka kwayo nayiphi na ingcaciso engachananga. ”

I-Baric kunye nezinye iingcali zezifo ezosulelayo zazibandakanyeka kuyilo impendulo. Ii-imeyile zibonisa iingxoxo zangaphakathi zeengcali kunye nefayile ye- Uyilo lwakwangoko yomhla kaFebruwari 4.

Uyilo lwangaphambili luchaze "izimvo zokuqala zeengcali" ukuba "idatha ekhoyo ye-genomic iyahambelana nendalo kwaye okwangoku akukho bungqina bokuba intsholongwane yenzelwe ukusasazeka ngokukhawuleza phakathi kwabantu." Esi sigwebo siyilwayo siphakamise umbuzo, phakathi kubazali: “[buza iingcali ukuba zongeze iindawo ezithile zokubopha iziza?]” Ikwaquka nombhalo osemazantsi kwizibiyeli: indaleko yee-coronaviruses ezinxulumene noko. ”

In Imeyile enye, yomhla kaFebruwari 4, ingcali ngezifo ezosulelayo uTrevor Bedford wathi: “Andizukuchaza iindawo ezibopha apha. Ukuba uqala ukulinganisa ubungqina kukho okuninzi ekufuneka kuqwalaselwe kuzo zombini ezi meko. ” Ngayo "yomibini le miboniso," iBedford ibonakala ibhekisa kwimvelaphi yeelebhu kunye nemeko yemvelaphi yendalo.

Umbuzo weziza ezibophelelayo ubalulekile kwingxoxo-mpikiswano malunga nemvelaphi yeSARS-CoV-2. Iindawo ezibophayo ezahlukileyo kwi-SARS-CoV-2's spike protein confer "Kufutshane kakhulu" ukubopha kunye nokungena kwintsholongwane kwiiseli zomntu, kwaye yenze i-SARS-CoV-2 yosasazeke ngakumbi kune-SARS-CoV. Oososayensi bathi indawo ezizodwa zokubopha zeSARS-CoV-2 zinokuvela ngenxa yoku endalo spillover endle okanye ngamabomu i laboratory Ukuhlaziywa kwakhona ngokhokho wendalo we-SARS-CoV-2.

The ileta yokugqibela epapashwe ngoFebruwari 6 khange zikhankanye iindawo ezibophelelayo okanye ukubakho kwemvelaphi yelebhu. Iyacacisa ukuba ulwazi oluthe kratya luyimfuneko ukumisela imvelaphi ye-SARS-CoV-2. Ileta ithi, “Iingcali zisazisile ukuba iinkcukacha ezongezelelekileyo zolandelelwano lwe-genomic ezivela kubume bomhlaba- nakwexeshana- iisampulu ezahlukeneyo zentsholongwane ziyafuneka ukumisela imvelaphi kunye nokudaleka kwentsholongwane. Iisampulu eziqokelelwe kwangethuba kuqhambuko lwaseWuhan kwaye iisampulu ezivela kwizilwanyana zasendle zingabaluleka kakhulu. ”

Iimeyile zibonisa ezinye iingcali zixoxa ngesidingo solwimi olucacileyo lokuphikisa into echazwe njenge "iingcinga zokuqhekeka" zemvelaphi yelabhoratri. UKristian Andersen, umbhali okhokelayo we iphepha elinempembelelo lezeNdalo Ndigxininisa imvelaphi yendalo ye-SARS-CoV-2, yathi uyilo lwakwangoko "lwalulukhulu, kodwa ndiyazibuza ukuba ingaba kufuneka sizinze ngakumbi kumcimbi wobunjineli." Uqhubeke wathi, “Ukuba enye yeenjongo zolu xwebhu kukuphikisa ezo nkolelo, ndicinga ukuba kubaluleke kakhulu ukuba sikwenze oko ngolwimi olucacileyo…”

In impendulo yakhe, I-Baric ijolise ekudluliseni isiseko sesayensi ngemvelaphi yendalo ye-SARS-CoV-2. “Ndicinga ukuba kufuneka sitsho ukuba oyena mntu usondeleyo kule ntsholongwane (96%) wachongwa kumalulwane ajikeleza emqolombeni eYunnan, China. Oku kuyenza icace gca imvelaphi yezilwanyana. ”

Yokugqibela ileta Ukusuka kubongameli be-NASEM abathathi ndawo kwimvelaphi yentsholongwane. Ithi, “Izifundo zophando ukuqonda ngcono imvelaphi ye-2019-nCoV kunye nendlela ezinxibelelana ngayo neentsholongwane ezifumaneka kumalulwane nakwezinye iintlobo sele ziqhubeka. Esona sizalwane sisondeleyo se-2019-nCoV sibonakala njenge-coronavirus echongwe kwiisampulu ezivela kwilulwane eziqokelelwe e-China. ” Ileta ekubhekiswa kuyo Mbini izifundo eziqhutywa yi-EcoHealth Alliance kunye neWuhan Institute of Virology. Zombini zibeka imvelaphi yendalo ye-SARS-CoV-2.

Kwiiveki ezimbalwa kamva, ileta kamongameli ye-NASEM yavela njengomthombo onegunya lomntu onempembelelo ingxelo yezenzululwazi epapashwe kwi Lancet egqithise ukuqiniseka ngakumbi malunga nemvelaphi ye-SARS-CoV-2. I-USRTK ixeliwe ngaphambili Umongameli we-EcoHealth Alliance uPeter Daszak wayila le ngxelo, eyathi "oososayensi abavela kumazwe amaninzi… bagqiba kwelokuba le coronavirus yavela kwizilwanyana zasendle." Esi sikhundla, ingxelo ithi, "sixhaswa ngakumbi yileta evela kubongameli be-US National Academies of Science, Engineering, and Medicine."

Ukuqeshwa kuka-Peter Daszak kunye namanye amahlakani e-EcoHealth Alliance Ikhomishini yeLancet COVID19 kunye noDaszak kwi Uphando loMbutho wezeMpilo weHlabathi Imvelaphi ye-SARS-CoV-2 ithetha ukuba ukuthembeka kwezi nzame kujongelwa phantsi ukungqubana komdla, nangokubonakala ngathi sele bewugwebe kwangaphambili lo mbandela.

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“Imiba esimele ukuyiphepha”

Ii-imeyile zeBaric zikwabonisa ummeli weNAS cebisa kwizazinzulu zase-US kufuneka "bayiphephe" imibuzo malunga nemvelaphi ye-SARS-CoV-2 kwiintlanganiso zamazwe amabini ababecwangcisa kunye neengcali zase-China ze-COVID-19. Ii-imeyile ngoMeyi nangoJuni 2020 zixoxa ngezicwangciso zeentlanganiso. Inxaxheba kwezenzululwazi zaseMelika, uninzi lwazo zingamalungu eNAS IKomiti emileyo yezifo ezasulelayo kunye nezisongelo zempilo zenkulungwane yama-21, Babandakanya uRalph Baric, Peter Daszak, David Franz, James Le Duc, Stanley Perlman, David Relman, Linda Saif, kunye Peiyong Shi.

The abathathi-nxaxheba base China kubandakanya uGeorge Gao, uZhengli Shi, kunye noZhiming Yuan. UGeorge Gao nguMlawuli we-CDC yase China. UZhengli Shi ukhokela uphando lwe-coronavirus eWuhan Institute of Virology, kwaye uZhiming Yuan nguMlawuli weWIV.

In i-imeyile kubathathi-nxaxheba baseMelika malunga neseshoni yocwangciso, iGosa eliPhezulu leNkqubo ye-NAS uBenjamin Rusek uchaze injongo yentlanganiso: “ukukugcwalisa kwimvelaphi yencoko, xoxa ngezihloko / imibuzo (uluhlu kwileta yesimemo sakho kwaye iqhotyoshelwe) kunye nemiba ekunokwenzeka ukuba thintela (imibuzo yemvelaphi, ezopolitiko)… ”

Ukuze ufumane inkcazelo engakumbi

Qhagamshela kwi-imeyile yaseYunivesithi yaseNorth Carolina u-Ralph Baric nge-imeyile enokufumaneka apha: Ii-imeyile zebaric (Iphepha le-83,416)

Ilungelo lase-US lokwazi ukuthumela amaxwebhu avela kwizicelo zethu zeerekhodi zoluntu ze uphando lwethu lwe-biohazards. Qaphela: Amaxwebhu e-FOI kwimvelaphi ye-SARS-CoV-2, iingozi zokufumana umsebenzi kunye neelebhu zokutya.

Izinto ezivela kwiingcali ze-coralvirus ze-imeyile zikaRalph Baric 

Eli phepha ludwelisa amaxwebhu kwii-imeyile zikaNjingalwazi uRalph Baric, e-US Right to Know efunyenwe ngesicelo seerekhodi zoluntu. UGqirha Baric yingcali ye-coronavirus kwiYunivesithi yaseNorth Carolina, eChapel Hill (UNC). Une kuphuhliswe ubuchule bemfuza ukuba ukuphucula ubukho besifo se-bat coronaviruses esele zikhona in ngentsebenziswano noGqirha Zhengli Shi kwiziko laseWuhan leVirology kunye ne-EcoHealth Alliance.

Ii-imeyile zibonisa iingxoxo zangaphakathi kunye nokuyilwa kwangoko kwincwadi engundoqo yesayensi malunga nemvelaphi ye-coronavirus, kunye nokukhanya okuthe kratya kubudlelwane phakathi kweengcali zaseMelika nezaseTshayina kwizifo ezosulelayo kunye nezifo ezosulelayo, kunye nendima yemibutho efana ne-EcoHealth Alliance kunye ne-National Academy of Sciences (NAS).

Nceda uthumele nge-imeyile nantoni na enomdla ekusenokwenzeka ukuba siphose kuyo sainath@usrtk.org, ukuze sibe nokuzibandakanya apha ngezantsi.

Izinto ezivela kwii-imeyile zeBaric

  1. UTracy McNamara, uNjingalwazi wePathology kwiYunivesithi yaseNtshona yezeMpilo ePomona, eCalifornia wabhala Ngomhla wamashumi amabini anesihlanu kwinyanga yoKwindla ngo-25: “I-Federal govt ichithe ngaphezulu kwe- $ 2020 yezigidi zeedola ukuxhasa i-Ajenda yoKhuseleko lwezeMpilo kwiHlabathi liphela ukunceda amazwe asaphuhlayo ukuba enze amandla okufumana / ukunika ingxelo / ukuphendula kwizoyikiso zobhubhane. I $ 1 yezigidi eyongezelelweyo ichithwe kwiprojekthi yePREDICT nge-USAID ikhangela iintsholongwane ezivela kumalulwane, kwiigundane nakwiinkawu phesheya kolwandle. Kwaye ngoku Iprojekthi yeVirome Global ifuna i-200 yezigidigidi zeedola ukuba zibaleke kwihlabathi liphela zizingela yonke intsholongwane ebusweni bomhlaba. Baya kufumana inkxaso-mali. Kodwa akukho nanye kwezi nkqubo eyenze abarhafi bakhuseleke kwalapha ekhaya. ” (ugxininiso kwasekuqaleni)
  2. UGqr.Jonathan Epstein, usekela-Mongameli weSayensi kunye nokuFikelela kwi-EcoHealth Alliance, bafuna isikhokelo sesicelo esivela kwi-Arhente yoPhando oluPhucukileyo lwe-Arhente yase-US (i-DARPA) malunga nokunxibelelana "nolwazi olunokusetyenziswa kolwazi olunokusetyenziswa kabini" (ngoMatshi 2018).
  3. Umanyano lwe-EcoHealth imali UGqirha Baric isixa esingachazwanga njenge-honarium (ngoJanuwari 2018).
  4. isimemo kwi-US National Academy of Sciences, Ubunjineli kunye noNyango (NASEM) kunye ne-Chinese Academy yezoLimo lwezoLimo (CAAS) I-China China Dialogue kunye neWorkshop malunga neMiceli mngeni yoSulelo oluKhulayo, uKhuseleko lweLebhu, uKhuseleko lwezeMpilo kwiHlabathi liphela kunye nokuziphatha okufanelekileyo ekusebenziseni iGene Editing kuPhando lwezifo eziSulelayo., Harbin, China, Jan 8-10, 2019 (Novemba 2018-Januwari 2019). Ukulungiselela email kunye a Imemorandam yokuhamba bonisa izazisi zabathathi-nxaxheba baseMelika.
  5. Isimemo se-NAS kwintlanganiso yeengcali zaseMelika nezaseTshayina ezisebenza ukulwa nezifo ezasulelayo nokuphucula impilo yehlabathi (ngoNovemba 2017). Intlanganiso ibibizwe yi-NAS kunye neLebhu yeSizwe yaseGalveston. Yenzeka ngoJanuwari 16-18, 2018, eGalveston, eTexas. A Imemorandam yokuhamba ibonisa izazisi zabathathi-nxaxheba baseMelika. Okulandelayo email bonisa ukuba uGqirha Zhengli Shi we-WIV ukhona entlanganisweni.
  6. NgoFebruwari 27, 2020, iBaric wabhala, "Ngalo mzuzu eyona mvelaphi yamalulwane, kwaye ndiyaqaphela ukuba yimpazamo ukucinga ukuba umamkeli zindwendwe ophakathi uyafuneka."
  7. Ngo-Matshi 5, 2020, i-Baric wabhala, “Abukho ubungqina bokuba le ntsholongwane yenziwe ngoochwephesha bezinto eziphilayo.”

Ukuze ufumane inkcazelo engakumbi

Ikhonkco kwii-imeyile zikaNjingalwazi uRalph Baric zingafumaneka apha: Ii-imeyile zebaric (~ 83,416 amaphepha)

Ilungelo lase-US lokwazi ukuthumela amaxwebhu ukusuka uphando lwethu lweBiohazards. Qaphela: Amaxwebhu e-FOI kwimvelaphi ye-SARS-CoV-2, iingozi zokufumana umsebenzi kunye neelebhu zokutya.

Novemba 24, 2020

Isazinzulu esinongquzulwano lomdla esikhokelayo Lancet I-COVID-19 ikhomishini kwi-virus imvelaphi

Kwiveki ephelile, Ilungelo laseMelika lokwazi ingxelo Isiteyitimenti esinefuthe kwiLancet esayinwe ngoososayensi abaziwayo abangama-27 malunga nemvelaphi yeSARS-CoV-2 ibiququzelelwe ngabasebenzi be-EcoHealth Alliance, iqela elingenzi nzuzo nelifumene izigidi zeedola kwinkxaso mali yomhlawuli werhafu waseMelika ukuze asebenzise i-coronaviruses yemfuza. kunye nososayensi kwiZiko laseWuhan leVirology (WIV). 

The Ingxelo kaFebruwari 18 wagweba "iingcamango zobuqhetseba" ezibonisa ukuba i-COVID-19 inokuba ivela elabhoratri, kwaye yathi izazinzulu "zigqibe ngokugqwesileyo" intsholongwane evela kwizilwanyana zasendle. Iimeyile ezifunyenwe yi-USRTK Uveze ukuba uMongameli we-EcoHealth Alliance uPeter Daszak wayila le leta wayilungiselela “ukuthintela ukuvela kwengxelo yezopolitiko.” 

I-Lancet ayiphumelelanga ukuveza ukuba abanye abantu abasayine le ngxelo banezikhundla kwi-EcoHealth Alliance, enegalelo kwezemali ekuphambukiseni imibuzo kude nokuba kungenzeka ukuba intsholongwane yavela elebhu.

Ngoku, iLancet ihambisa impembelelo ngakumbi kwiqela elinokungqubana komdla kumbuzo obalulekileyo wezempilo woluntu malunga nemvelaphi yesifo. Ngomhla kaNovemba 23, iLancet enegama elithi a ipaneli yamalungu ali-12 entsha kwiKhomishini yeLancet COVID 19. Usihlalo weqela elitsha lokuphanda "Imvelaphi, ukusasazeka kwangoko kwesifo, kunye nesisombululo esinye sezeMpilo kwizoyikiso zobhubhane zangomso" akekho omnye ngaphandle kukaPeter Daszak we-EcoHealth Alliance. 

Isiqingatha seqela labasebenzi- kubandakanya iDaszak, iHume Field, uGerald Keusch, uSai Kit Lam, uStanley Perlman noLinda Saif - nabo babesayine ingxelo kaFebhuwari 18 abathi bayayazi imvelaphi yentsholongwane kwiveki nje engephi emva kweMpilo yeHlabathi. Umbutho ubhengeze ukuba isifo esibangelwe yinoveli yecoronavirus siyakuthiwa COVID-19. 

Ngamanye amagama, ubuncinci isiqingatha somsebenzi weKhomishini ye-Lancet ye-COVID kwimvelaphi ye-SARS-CoV-2 ibonakala ngathi ibisele isigwebo kwangaphambili phambi kokuba uphando luqale. Oku kujongela phantsi ukuthembeka kunye negunya lomsebenzi.

Imvelaphi ye-SARS-CoV-2 yile iseyimfihlakalo kwaye uphando olucokisekileyo nolunokuthenjwa lungabaluleka ekuthinteleni ubhubhane olandelayo. Uluntu lufanelwe luphando olungangcoliswanga ziingxabano zomdla.

Uhlaziyo (ngoNovemba 25, 2020): UPeter Daszak naye uchongiwe kwi- Iqela labantu abali-10 boMbutho wezeMpilo weHlabathi ukuphanda ngemvelaphi ye-SARS-CoV-2.

Novemba 18, 2020

Umbutho we-EcoHealth Alliance wenza amalungiselelo esiteyitimenti sososayensi “ngemvelaphi yendalo” ye-SARS-CoV-2

Hlaziya i-2.15.21 -I-imeyile entsha yeDaszak: “Akukho sidingo sokuba utyikitye 'iNgxelo' uRalph !!

I-imeyile efunyenwe yi-US Right to Know ibonisa ukuba a ingxelo kwi Lancet Ababhali bezesayensi bezempilo abaziwayo be-27 begxeka "iingcamango zobuqhetseba ezibonisa ukuba i-COVID-19 ayinayo imvelaphi yendalo" yayiququzelelwe ngabasebenzi be-EcoHealth Alliance, iqela elingenzi nzuzo eliye ifumene izigidi zeedola of Umrhafi wase-US inkxaso mali yemfuza ilawule iintsholongwane ze-Corona kunye nososayensi kwi IZiko leNzululwazi yeWuhan.

Ii-imeyile ezifunyenwe ngezicelo zeerekhodi zoluntu zibonisa ukuba uMongameli we-EcoHealth Alliance uPeter Daszak wayila Lancet Isiteyitimenti, kwaye wayezimisele "Ingabonakali njengevela kumbutho omnye okanye umntu omnye" kodwa kunokuba kubonwe njenge “Ileta nje evela kwizazinzulu eziphambili”. UDaszak ubhale ukuba ufuna "ukunqanda ukuvela kwengxelo yezopolitiko".

Ileta yezazinzulu yavela Lancet Nge-18 kaFebruwari, kwiveki nje enye emva kokuba uMbutho wezeMpilo weHlabathi wabhengeza ukuba isifo esibangelwe yinoveli yecoronavirus sizakuthiwa yi COVID-19.

Ababhali abangama-27 “bazigxeka kabukhali iingcamango zelenqe ezibonisa ukuba i-COVID-19 ayinayo imvelaphi yendalo,” kwaye baxela ukuba oososayensi abavela kumazwe amaninzi "bagqiba kwelokuba le coronavirus yavela kwizilwanyana zasendle." Le leta ibingafakwanga izingqinisiso zesayensi zokuphikisa imvelaphi yeelebhu yentsholongwane. Isazinzulu esinye, uLinda Saif, ubuze nge-imeyile ukuba ingaba iya kuba luncedo "Ukongeza nje isitetimenti esinye okanye ezi-2 ukuxhasa ukuba kutheni i-NCOV ingeyiyo intsholongwane eyilebhu kwaye iyenzeka ngokwendalo? Kubonakala ngathi kubalulekile ukuphikisa inzululwazi ngamabango anje! ” UDaszak uphendule wathi, "Ndicinga ukuba kufanele ukuba sinamathele kwingxelo ebanzi. "

Ukukhula kweefowuni ukuphanda iZiko laseWuhan leVirology njengomthombo onokubakho weSARS-CoV-2 ukhokelele ukwanda koqwalaselo Umanyano lwe-EcoHealth. Ii-imeyile zibonisa indlela amalungu e-EcoHealth Alliance adlale ngayo indima yokuqala ekubunjweni kwemibuzo malunga nemvelaphi yeelebhu ze-SARS-CoV-2 njenge "iingcinga ezinqabileyo ekufuneka kujongwane nazo," njenge UDaszak uxelele Guardian.

Nangona ibinzana elithi "EcoHealth Alliance" livele kube kanye kuphela Lancet Isiteyitimenti, ngokunxulumana nombhali-mbhali uDaszak, abanye ababhali basebenzisana nabo banolwalamano oluthe ngqo kwiqela elingachazwanga njengongquzulwano lomdla. URita Colwell noJames Hughes banjalo amalungu yeBhodi yaBalawuli ye-EcoHealth Alliance, UWilliam Karesh nguSekela Mongameli oLawulayo weqela lezeMpilo noMgaqo-nkqubo, kwaye Intsimi yeHume nguMcebisi ngezeNzululwazi noMgaqo-nkqubo.

Ababhali beengxelo bakwathi "ukwabiwa ngokukhawuleza, okuvulekileyo nokungafihlisiyo kwedatha malunga noku kuqhambuka ngoku kusongelwa ngamahemuhemu kunye nolwazi olungelulo malunga nemvelaphi yalo." Namhlanje, nangona kunjalo, kuncinci okwaziwayo malunga nemvelaphi ye-SARS-CoV-2, kunye nophando kwimvelaphi yayo ngoku iWorld Health Organization kwaye Lancet Ikhomishini yeCoverV-19 ibe igutyungelwe yimfihlo kwaye zixutywe ngu ukungqubana kwemidla.

UPeter Daszak, uRita Colwell, kunye Lancet Umhleli uRichard Horton khange anike zinkcazo ukuphendula izicelo zethu zeli bali.

Ukuze ufumane inkcazelo engakumbi

Ikhonkco kwibhetshi iphela ye-EcoHealth Alliance ye-imeyile inokufumaneka apha: I-imeyile ye-EcoHealth Alliance: kwiDyunivesithi yaseMaryland (Iphepha le-466)

Ilungelo lase-US lokwazi ukuthumela amaxwebhu afunyenwe ngenkululeko yoluntu yokufumana ulwazi (FOI) yezicelo uphando lwethu lweBiohazards Kwiposi yethu: Amaxwebhu e-FOI kwimvelaphi ye-SARS-CoV-2, iingozi zokufumana umsebenzi kunye neelebhu zokutya.

Izithuba ezihambelanayo

Novemba 12, 2020

Ijenali yendalo yongeza "inqaku lomhleli" elibonisa inkxalabo malunga nokuthembeka kwesifundo esiqhagamshela i-pangolin coronaviruses kwimvelaphi ye-SARS-CoV-2

Nge-9 kaNovemba ka-2020, i-US Ilungelo lokwazi khululwe imeyile nababhali abaphezulu be Liu okqhubekayo. kwaye Xiao okqhubekayo., Nabasebenzi nabahleli e Izifo ze-PLoS kwaye indalo oolindixesha. Ezi zifundo zibonelele ngobungqina besayensi kwi-zoonotic hypothesis yokuba ii-coronaviruses ezinxulumene ngokusondeleyo ne-SARS-CoV-2 zijikeleza endle, kwaye i-SARS-CoV-2 inomthombo wezilwanyana zasendle. NgoNovemba 11, 2020, indalo wongeze eli nqaku lilandelayo kwiphepha likaXiao et al. “Inqaku loMhleli: Abafundi bayaziswa ukuba inkxalabo iphakanyisiwe malunga neesampulu zepangolin ezichazwe kweli phepha kunye nobudlelwane bazo kwiisampulu zepangolin ezipapashwe ngaphambili. Amanyathelo afanelekileyo okuhlela aya kuthathwa xa lo mba usonjululwe. ”

Inqaku linokubonwa apha: https://www.nature.com/articles/s41586-020-2313-x

Novemba 9, 2020

Indalo kunye ne-PLoS Iintsholongwane zibonakalisa ubunyani besayensi kwizifundo eziphambili zokudibanisa i-pangolin coronaviruses kwimvelaphi ye-SARS-CoV-2

Bhalisa ku fumana uhlaziyo kwiBhlogazards Blog.

NguSainath Suryanarayanan, PhD 

Apha, sinika ii-imeyile zethu ngababhali abaphezulu be- Liu okqhubekayo. kwaye Xiao okqhubekayo., kunye nabahleli be Izifo ze-PLoS kwaye indalo. Sikwazisa nengxoxo enzulu yemibuzo kunye neenkxalabo eziphakanyiswe zezi imeyile, ezibeka ukuthandabuza ubunyani bezi zifundo ziphambili ngemvelaphi yenoveli coronavirus SARS-CoV-2 ebangela i-COVID-19. Bona ingxelo yethu kwezi imeyile, Ukunyaniseka kwezifundo eziphambili kwimvelaphi yecoronavirus ngokungathandabuzekiyo; Ijenali zesayensi eziphanda (11.9.20)


Unxibelelwano nge-imeyile noGqirha Jinping Chen, Umbhali omkhulu kaLiu et al:


Ii-imeyile zikaGqirha Jinping Chen ziphakamisa inkxalabo kunye nemibuzo. 

1- Liu okqhubekayo. (2020) bahlanganisa ngokulandelelana kwabo ipangolin coronavirus genome ulandelelwano olusekwe kwii-coronaviruses ezisampuliweyo kwii-pangolin ezintathu, iisampulu ezimbini ezivela kwibhetshi ehanjiswe ngokungekho mthethweni ngo-Matshi 2019, kunye nesampulu enye evela kwibhetshi eyahlukileyo eyabanjwa ngoJulayi 2019. , apho izazinzulu zifuneka ukuba zifake idatha yolandelelwano ukuqinisekisa ukungqinisisa okuzimeleyo kunye nokuzala kwakhona kweziphumo ezipapashiweyo, eziqulathe idatha yolondolozo yokufunda (SRA) ngokulandelelana kweesampulu ezimbini zika-Matshi 2019 kodwa ilahlekile kwidatha kaJulayi 2019. Emva kokubuzwa ngale sampulu ilahlekileyo, ethi uGqirha Jinping Chen ayichaze njenge-F9, uGqirha Jinping Chen wathi: “Idatha eluhlaza yezi sampuli zintathu inokufunyanwa phantsi kwenombolo ye-NCBI ye-PRJNA573298, kunye ne-BioSample ID yayingu-SAMN12809952, SAMN12809953, kunye SAMN12809954, ngaphezu koko, umntu ngamnye (F9) ovela kwibhetshi eyahlukileyo wayenethemba, idatha eluhlaza inokubonwa kwi-NCBI SRA SUB 7661929, eziza kukhutshwa kungekudala ngokuba sinenye i-MS (iphantsi koqwalaselo)”(Ugxininiso lwethu).

Imalunga nelo Liu et al. khange bapapashe idatha engqinelana ne-1 yee-3 zee-pangolins iisampulu abazisebenzisileyo ukudibanisa ukulandelelana kwazo kwe-pangolin coronavirus genome. UGqirha Jinping Chen naye khange abelane ngale datha xa ebuzwa. Isiqhelo kwisayensi kukupapasha kunye / okanye nokwabelana ngedatha eya kuvumela abanye ukuba baqinisekise ngokuzimeleyo kwaye bavelise iziphumo. Ingaba wenze kanjani Izifo ze-PLoS Vumela uLiu et al. ukuphepha ukupapasha idatha yesampulu ebalulekileyo? Kutheni le nto uGqirha Jinping Chen engabelani ngedatha emalunga nesampulu yesithathu yepangolin? Kutheni uLiu et al. Ngaba ufuna ukukhupha idatha engashicilelwanga emalunga nale sampuli yesithathu yepangolin njengenxalenye yesifundo esingeniswe kwiphephancwadi elahlukileyo? Inkxalabo apha yeyokuba izazinzulu ziya kunika gwenxa isampulu yepangolin elahlekileyo evela kuLiu et al. Kwisifundo esahlukileyo, okwenza kube nzima kwabanye ukuba emva koko balandele iinkcukacha ezibalulekileyo malunga nesampulu yepangolin, njengomxholo apho isampulu yepangolin yayiqokelelwa khona.

UGqirha uJinping Chen uyiphikile into yokuba uLiu et al. ndibenolwalamano noXiao et al.'s (2) indalo ukufunda. Ubhale wathi: "Singenise iphepha lethu le-PLOS Pathogens ngoFebruwari 14, 2020 phambi kwephepha leNdalo (Isalathiso 12 kwiphepha lethu le-PLOS pathogens, bangenise ngoFebruwari 16, 2020 ukusukela kumhla wokungeniswa kwabo kwiNdalo), iphepha lethu lezifo ze-PLOS chaza ukuba i-SARS-Cov-2 ayiveli kwipangolin coronavirus ngqo kwaye ipangolin ayingombamkeli ophakathi. Sasiwazi umsebenzi wabo emva kwengcaciso yeendaba zabo ngoFebruwari 7, 2020, kwaye sinezimvo ezahlukileyo kunye nabo, amanye amaphepha amabini (iiVirus kunye neNdalo) adwelisiwe kwiphepha le-PLOS Pathogen njengamaphepha esalathiso (inombolo yesalathiso ye-10 kunye ne-12), singamaqela ophando ahlukeneyo kubabhali bephepha leNdalo, kwaye akukho buhlobo phakathi kwabo, yaye sithathe iisampulu ngolwazi olunenkcukacha zesampula kwiziko lokuhlangula lezilwanyana zasendle laseGuangdong ngoncedo oluvela kuJiejian Zou kunye noFanghui Hou njengababhali bethu kwaye asazi ukuba iisampulu zephepha leNdalo zivela phi. ” (ukunyanzeliswa kwethu)

La manqaku alandelayo aphakamisa ukuthandabuza malunga nezimangalo zikaGqirha Chen ngasentla: 

Liu okqhubekayo. (2020), Xiao et al (2020) kunye noLiu et al. (2019) babelane ngababhali abalandelayo: UPing Liu noJinping Chen babengababhali kwi2019 Iintsholongwane iphepha kunye ne2020 Izifo ze-PLoS iphepha, umbhali omkhulu uWu Chen kwiXiao et al. (2020) wayengumbhali-mbhali we2019 Iintsholongwane iphepha, kunye noJiejian Zhou kunye noFanghui Hou babengababhali kuzo zombini iXiao et al. kunye noLiu et al. 

Zombini ezi mibhalo zibhaliweyo zafakwa kwiseva yoshicilelo loluntu bioRxiv ngomhla ofanayo: ngoFebruwari 20, 2020. 

c Xiao okqhubekayo. “Iisampulu zepangolin ezinikwe igama kwakhona zapapashwa okokuqala nguLiu et al. [2019] Iintsholongwane ngaphandle kokukhankanya isifundo sabo njengenqaku lokuqala elichaze ezi iisampulu, kwaye basebenzise idatha ye-metagenomic kwezi sampuli kuhlalutyo lwabo "(UChan noZhan). 

Liu et al. pangolin coronavirus genome epheleleyo 99.95% efanayo kwinqanaba le-nucleotide ukuya kwi-pangolin coronavirus genome epheleleyo epapashwe ngu-Xiao et al. Angakwazi njani uLiu et al. Ndivelise i-genome epheleleyo eyi-99.95% efanayo (kuphela ~ 15 ye-nucleotides umahluko) kuXiao et al. ngaphandle kokwabelana ngedatha kunye nohlalutyo?

Xa amaqela ophando ohlukeneyo ngokuzimeleyo efika kwiiseti ezifanayo zesigqibo malunga nombuzo onikiweyo wophando, oko kukonyusa ukubakho kwenyani yamabango abandakanyekayo. Inkxalabo apha kukuba uLiu et al. kunye noXiao et al. khange kwenziwe ngokuzimeleyo kwizifundo njengoko kufunwa nguGqirha Chen. Ngaba kukho naluphi na unxibelelwano phakathi kukaLiu et al. kunye noXiao et al. ngokubhekisele kuhlalutyo lwabo nakupapasho? Ukuba kunjalo, lwalungakanani kwaye lwalunjani olo nxibelelaniso? 

Kutheni le nto uLiu et al. ayenzi ukuba ifumaneke esidlangalaleni idatha eluhlaza yokulandelelanisa i-amplicon ababeyisebenzisa ukudibanisa i-pangolin coronavirus genome? Ngaphandle kwale datha eluhlaza, i-pangolin coronavirus genome ehlanganiswe ngu-Liu et al., Abanye abanakuzimela ngokuzimeleyo kwaye bavelise iziphumo zika-Liu et al. Njengoko kukhankanyiwe ngaphambili, into eqhelekileyo kwinzululwazi kukupapasha kunye / okanye nokwabelana ngayo yonke idatha enokuvumela abanye ukuba baqinisekise ngokuzimeleyo kwaye bavelise iziphumo. Sacela uGqirha uJingping Chen ukuba abelane ngeLiu et al. Idatha eluhlaza yokulandelelana kwe-amplicon. Uphendule ngokwabelana no-Liu et al. Iziphumo ze-RT-PCR zokulandelelana kwemveliso, ezingezizo idatha ye-amplicon eluhlaza esetyenziselwa ukudibanisa i-pangolin coronavirus genome. Kutheni uGqirha Jinping Chen emathandabuzo ukukhupha idatha eluhlaza eya kuvumela abanye ukuba baqinisekise ngokuzimeleyo Uhlalutyo lukaLiu et al.

4- Liu okqhubekayo. Iintsholongwane (2019) yapapashwa ngo-Okthobha u-2019 kwaye ababhali bayo babeyifakile i-pangolin coronavirus (ngokulandelelana funda ugcino) idatha ye-SRA kunye ne-NCBI ngoSeptemba 23, 2019, kodwa ndalinda de January 22, 2020 ukwenza le datha ifikeleleke esidlangalaleni. Izazinzulu zihlala zikhupha idatha eluhlaza yokulandelelana kwe-genomic kulwazi olufikeleleka esidlangalaleni ngokukhawuleza emva kokupapashwa kwezifundo zabo. Esi senzo siqinisekisa ukuba abanye banokufikelela ngokuzimeleyo, baqinisekise kwaye basebenzise idatha. Kutheni le nto uLiu et al. 2019 linda iinyanga ezi-4 ukwenza idatha yabo ye-SRA ifikeleleke esidlangalaleni? UGqirha Jinping Chen ukhethe ukungawuphenduli ngokuthe ngqo lo mbuzo wethu kwimpendulo yakhe ngo-Novemba ngo-9, 2020.

Saye sanxibelelana noGqirha Stanley Perlman, Izifo ze-PLoS Umhleli kaLiu et al. kwaye yile nto ebefanele ukuyithetha.

Ngokukodwa, uGqirha Perlman uvumile ukuba:

  • "I-PLoS Pathogens iphanda eli phepha ngokweenkcukacha" 
  • Akazange "aqinisekise ubunyani besampulu kaJulayi 2019 ngexesha lokuphononongwa kwangaphambili koontanga"
  • “[C] ii-oncerns malunga nokufana phakathi kwezi zifundo zibini [Liu et al. noXiao et al.] zavela kuphela emva kokupapashwa kwezi zifundo zombini. ”
  • Akakhange abone nayiphi na idatha ye-amplicon ngexesha lokuphononongwa koontanga. Ababhali banikezele ngenombolo yokungena kwi-genome ehlanganisiweyo… nangona emva kokupapashwa kuye kwavela ukuba inombolo yokungena edweliswe kwiNgxelo yokuFumaneka kweDatha ayichanekanga. Impazamo kunye nemibuzo ejikeleze idatha eluhlaza yokulandelelana kokulungiswa okwangoku kuyaphendulwa njengenxalenye yetyala lasemva kokupapashwa. ”

Xa saqhagamshelana Izifo ze-PLoS neenkxalabo zethu malunga noLiu et al. sikufumene oku kulandelayo Impendulo evela kuMhleli oPhezulu weqela leenqobo ezisisiseko zokupapasha iPLoS:

Iileta ezivela kwiXiao et al.

Ngo-Okthobha i-28, i Umhleli oyiNtloko weSayensi yezebhayoloji indalo uphendule (ngezantsi) ngebinzana eliphambili "siyithatha le micimbi nzulu kwaye siya kuwujonga lo mbandela uwuphakamisa apha ngezantsi ngononophelo olukhulu." 

Nge-30 ka-Okthobha, uXiao et al. ekugqibeleni ikhutshwe esidlangalaleni idatha yabo yokulandelelana kwe-amplicon eluhlaza. Nangona kunjalo, njengopapasho lwesi siqwenga, idatha yolandelelwano lwe-amplicon engeniswe nguXiao et al. ilahlekile ezona fayile zedatha eluhlaza ezinokuvumela abanye ukuba bahlangane kwaye baqinisekise ukulandelelana kwazo kwepangolin coronavirus genome.

Imibuzo ebalulekileyo isasele efuna ukuqwalaselwa: 

  1. Ngaba i-pangolin coronaviruses iyinyani? Isihloko se Umzobo 1e kwiXiao et al. Ithi: “Amasuntswana entsholongwane abonwa kwizicwili ezinamalungu amabini kumfanekiso osasaza i-electron microscopy ethathwe kwiseli yeseli yeVero E6 efakwe isitya esinamandla esingaphezulu kwethishu yamaphaphu evela kwipangolin enye, ne-morphology ebonisa i-coronavirus.” Ukuba uXiao et al. yodwa i-pangolin coronavirus, ngaba bangabelana ngesampulu yentsholongwane kunye nabaphandi abangaphandle kwe China? Oku kunokuhamba indlela ende ekuqinisekiseni ukuba le ntsholongwane ikhona kwaye ivela kwizicwili zepangolin.
  2. Kwangoko ngo-2020, okanye ngo-2019 Liu okqhubekayo., Xiao okqhubekayo., Lam kunye al. kwaye UZhang et al. bayazi ukuba bazakupapasha iziphumo ngokusekwe kwidathasethi efanayo?
    a. Ngaba bekukho naluphi na ulungelelwaniso kuthathelwa ingqalelo ukuba enye yashicilelwa ngo-Februwari 18 kwaye ezintathu zanyulwa kwangaphambili ngo-Februwari 20?
    b. Kutheni le nto uLiu et al. (2019) abenzi ukulandelelana kwabo kufunde idatha yogcino ifikeleleke esidlangalaleni ngomhla ababeyifaka kwiziko ledatha leNCBI? Kutheni le nto belinde kude kube nge-22 kaJanuwari ngo-2020 ukwenza le pangolin coronavirus yokulandelelana kwedatha esidlangalaleni.
    c. Phambi kukaLiu et al. 2019 Iintsholongwane idatha ikhutshwe kwi-NCBI ngoJanuwari 22, 2020, ngaba le datha yayifikeleleka kwabanye abaphandi e-China? Ukuba kunjalo, yeyiphi idathabheyisi eyayiyipangolin coronavirus yokulandelelana kwedatha egcinwe kuyo, ngubani owayenokufikelela, kwaye yafakwa nini idatha yenziwa yafikeleleka?
  3. Ngaba ababhali bazakusebenzisana nophando oluzimeleyo lokulandela umkhondo wezi sampuli zepangolin ukubona ukuba ezinye iintsholongwane ezifana ne-SARS-CoV-2-ezinje ngezo zingafunyanwa ngo-Matshi ukuya ku-Julayi 2019 iibhetshi zezilwanyana ezifihliweyo- ezinokubakho njengeesampulu ezibandayo okanye usaphila eGuangdong Wildlife Rescue Centre?
  4. Ngaba ababhali bazakusebenzisana nophando oluzimeleyo ukubona ukuba abathubelezisi (ngaba bavalelwa?

Novemba 5, 2020

Wamkelekile kwiBhlogazards Blog

NgoJulayi 2020, i-US Right to Know yaqala ukungenisa izicelo zerekhodi zikarhulumente ekufuneni idatha evela kumaziko oluntu kumzamo wokufumanisa into eyaziwayo malunga nemvelaphi yenoveli coronavirus SARS-CoV-2, ebangela isifo Covid-19. Siphanda ngeengozi, ukuvuza kunye nokunye ukwenzakala kwiilebhu apho kugcinwa khona izifo ezinokubangela ubhubhane kwaye ziguqulwe, kunye nemingcipheko yezempilo yophando lwe-gain-of-function (GOF), ebandakanya ukuvavanywa kwezi ntsholongwane ukwandisa uluhlu lwazo, ukuhanjiswa okanye ukubulala.

Kule bhlog, siza kuthumela uhlaziyo kumaxwebhu esiwafumanayo kunye nolunye uphuhliso kuphando lwethu.

I-US Ilungelo lokwazi yi iqela lophando kugxilwe ekukhuthazeni ukungafihli kwempilo yoluntu. Sisebenza kwihlabathi liphela ukubhengeza ukungalunganga komdibaniso kunye nokusilela kukarhulumente okugrogrisa ukuthembeka kwenkqubo yethu yokutya, okusingqongileyo kunye nempilo yethu. Ukusukela ngo-2015, thina ufumene, thunyelwa kwi-intanethi kwaye ixelwe kumawakawaka oshishino kunye namaxwebhu aseburhulumenteni, kubandakanya amaninzi afunyenwe ngokunyanzelwa komthetho kwemithetho yeerekhodi evulekileyo.

Uphando lwethu kwii-biohazards lukhokelwa nguSainath Suryanarayanan, Ph.D. Idilesi ye-imeyile sainath@usrtk.org.

Ngolwazi oluthe kratya malunga nophando lwethu lwe-biohazards, nceda ubone:

Bhalisa kwincwadana yethu. Fumana uhlaziyo lweveki kwi-inbox.