ʻAʻohe manaʻo loiloi o nā hoa no ka hoʻohui i ka ʻike kumu coronavirus koʻikoʻi?

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Ka mangalepa Nature ʻaʻole i loiloi i ka hilinaʻi o nā kuleana koʻikoʻi i hana ʻia i Nowemapa 17 hoʻohui a like ma nā ʻōpeʻapeʻa kumu o ka moʻolelo coronavirus SARS-CoV-2, nā leka me Nature manaʻo nā limahana.

Ma Pepeluali 3, 2020, ua hōʻike ka ʻepekema Wuhan Institute of Virology i ka ʻike ʻana i kahi pili kokoke loa o ka SARS-CoV-2, kahi cor corona virus i kapa ʻia ʻo RaTG13. Kahiwa13 ua lilo i kikowaena i ke kuhiakau i hoʻokumu ʻia ʻo SARS-CoV-2 i ka holoholona lōhiu.

ʻO nā helu ʻōlelo hoʻohui pane ʻole ʻia ninau e pili ana i ka hōʻoia o RaTG13. Ua wehewehe nā mea kākau, Zhou et al., Ua loaʻa iā RaTG13 ma 2012-2013 "i kahi mineshaft i haʻalele ʻia ma ka moku ʻo Mojiang, ka moku ʻo Yunnan," kahi ʻeono mau minia i ʻeha. huʻihuʻi respiratory respiratory syndrome ma hope o ka hōʻike ʻia i nā f bat bathes, a ʻekolu i make. Nā noiʻi ʻana o ka hiki i nā hōʻailona o nā mea minia maʻi ke hāʻawi i nā hōʻailona koʻikoʻi e pili ana i nā kumu o SARS-CoV-2. Zhou et al. ua hōʻike i ka loaʻa ʻole o nā coronavirus e pili ana i ka SARS i nā laʻana serum i mālama ʻia o nā mea miners maʻi, akā ʻaʻole lākou i kākoʻo i kā lākou mau koi me nā ʻikepili a me nā ʻano e pili ana i kā lākou hoʻokolohua a me nā hoʻokolohua hoʻokolohua.

Loaʻa ka ʻole o ka ʻikepili koʻikoʻi i ka addendum hāpai hou i nā nīnau e pili ana i ka hilinaʻi o ka Zhou et al. hoʻopaʻa haʻawina. Ma Nowemapa 27, Ua noi ʻo US Right to Know Nature ninau e pili ana i nā kuleana o ka addendum, a noi ʻia i kēlā Nature paʻi i nā ʻikepili kākoʻo āpau a Zhou et al. ua hāʻawi paha.

Ma Kekemapa 2, Nature Ke poʻo o nā kamaʻilio Bex Walton wahi a ʻo ia ke kumu Zhou et al. ua "pololei akā maopopo ʻole" ka hoʻopaʻa ʻana, a ua kūpono ka hoʻohui anuu hope-paʻi no ka wehewehe ʻana. Ua hoʻohui ʻo ia: "E pili ana i kāu mau nīnau, e kuhikuhi mākou iā ʻoe e hoʻokokoke i nā mea kākau o ka pepa no nā pane, e like me ʻaʻole pili kēia mau nīnau i ka noiʻi a mākou i paʻi ai akā i nā noiʻi ʻē aʻe i mālama ʻia e nā mea kākau, ʻaʻole hiki iā mākou ke ʻōlelo ”(koʻikoʻi iā mākou). ʻOiai ʻo kā mākou nīnau e pili ana i ka noiʻi i wehewehe ʻia i ka addendum, ka Nature Hōʻike ka ʻōlelo a ka lunamakaʻāinana ʻaʻole i loiloi ʻia kā addendum a Zhou et al. ma ke ʻano he noiʻi.

Ua nīnau mākou he nīnau nīnau ma Kēkēmapa 2: "ua kau ʻia kēia addendum i kekahi loiloi ʻia e nā hoa a me / a i ʻole ka hoʻoponopono hoʻoponopono ʻana e Nature? ” ʻAʻole i pane pololei ʻo Ms. Walton; ʻo ia wahi a: "Ma ka laulā, e loiloi kā mākou mea hoʻoponopono i nā manaʻo a i ʻole nā ​​hopohopo i hāpai ʻia me mākou i ka manawa mua, e nīnau ana i nā mea kākau, a e ʻimi ana i nā ʻōlelo aʻoaʻo mai nā loiloi hoa a me nā loea ʻē aʻe inā manaʻo mākou he pono. ʻAʻole hiki iā mākou ke ʻōlelo i ka mālama pilikino ʻana i nā hihia pākahi.

No ka Nature manaʻo i ka hoʻohui he a ka hope-hoʻopuka hou, a ʻaʻole ia e hoʻokau i ka post post addenda i nā kūlana loiloi loiloi like e like me nā paʻi mua, me he mea lā ʻo Zhou et al. ʻAʻole i hoʻomoe ʻia e addendum.

ʻAʻole pane nā mea kākau ʻo Zhengli Shi lāua ʻo Peng Zhou iā ia mākou nīnau e pili ana i ko lakou Nature pākuʻi

Ke kūpono o nā noi nui e pili ana i ke kumu o ka coronavirus me ke kānalua; nā puke pai ʻepekema e ʻimi nei

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Na Carey Gillam

Mai ka ka laha ʻana o COVID-19 i ke kūlanakauhale Kina o Wuhan i Kēkēmapa 2019, ua ʻimi nā ʻepekema no nā kuhi e pili ana i ke ala ʻana o kāna agena causative, ka puke coronavirus SARS-CoV-2. ʻO ka wehe ʻana i ke kumu o ka SARS-CoV-2 hiki ke lilo i mea koʻikoʻi no ka pale ʻana i nā maʻi e hiki mai ana.

Ho? Oponopono o ʻehā kiʻekiʻe Profile haʻawina i paʻi ʻia ma mua o kēia makahiki i hāʻawi i ka ʻepekema hilinaʻi i ke kuhiakau i hoʻokumu ʻia ʻo SARS-CoV-2 i loko o nā opeapea a laila lele i nā kānaka ma o kahi ʻano anteater i kapa ʻia he pangolin - i waena o nā holoholona hihiu i kālepa nui ʻia ma ka honua. ʻOiai kēlā kumumanaʻo kikoʻī pili pū ana i nā pangolins hoʻēmi nui ʻia, nā noiʻi ʻehā i kapa ʻia ʻo "nā pepa pangolin" e hoʻomau i ka hāʻawi ʻana i ke kākoʻo no ka manaʻo e pili kokoke ana nā coronavirus iā SARS-CoV-2 e hoʻopuni i ka nahelehele, ʻo ia hoʻi ka SARS-CoV-2 i hoʻokumu iā COVID-19 mai kahi kumu holoholona hihiu mai. 

ʻO ka nānā ʻana i kahi kumu holoholona hihiu, ke kumumanaʻo "zoonotic", ua lilo i mea nui i ke kūkākūkā honua e pili ana i ka maʻi, e kuhikuhi ana i ka lehulehu mai kahi ka hiki i hoʻomaka paha ka maʻi maʻi i loko o kahi keʻena hoʻokolohua aupuni Kina - ka ʻO Wuhan Institute of Virology.

Ua aʻo ʻo US Right to Know (USRTK), eia naʻe ʻelua o nā pepa ʻehā e hoʻokumu ana i ke kumumanaʻo zoonotic e kīnā ʻole ana, a ʻo nā mea hoʻoponopono i nā puke pai i paʻi ʻia ai nā pepa. Nā Polokalamu PLoS a Nature - ke ʻimi nei i ka ʻikepili koʻikoʻi ma hope o nā noi a pehea e kālailai ʻia ai ka ʻikepili. Hōʻike like nā ʻē aʻe ʻelua i pilikia kīnā ʻole.

ʻO nā pilikia me nā pepa noiʻi e hāpai i nā "nīnau a me nā hopohopo koʻikoʻi" e pili ana i ka pono o ke kumumanaʻo zoonotic āpau, e like me ʻO Kauka Sainath Suryanarayanan, he biologist a me sociologist o ka ʻepekema, a me ka ʻepekema limahana o USRTK.  ʻAʻohe o ka ʻikepili i lawa ka hilinaʻi ʻia, nā ʻikepili i hōʻoia ʻia me kahi kaʻawale o ka loiloi a me ka hoʻoponopono ʻana o nā hoa, e like me kā Dr. Suryanarayanan. 

E ʻike i kāna mau leka uila me nā mea kākau kiʻekiʻe o nā pepa a me nā mea hoʻoponopono puke pai, a me ka hoʻopili ʻana. ʻO ke kūlohelohe a me PLoS Pathogens ʻimi i ka ʻepekema ʻoiaʻiʻo o nā noi nui e hoʻopili ana i nā corolavirus pangolin i ke kumu o SARS-CoV-2.

Nā luna aupuni aupuni Kina paipai mua i ka manaʻo ʻo ke kumu o ka agena causal no COVID-19 i loko o kānaka i hele mai mai kahi holoholona hihiu i Kekemapa. Ua kākoʻo nā ʻepekema i kākoʻo ʻia e ke aupuni Kina i kēlā kumumanaʻo i ʻehā mau noiʻi ʻokoʻa i waiho ʻia i nā puke pai ma waena o Pepeluali 7 a me 18.

ʻO ka Hui Misiona Hui Hui Kina a ka World Health Organization e ʻimi nei i ka puka a hoʻolaha ʻana o COVID-19 ma Kina i ʻōlelo ʻia ma Pepeluali : "No ka loaʻa ʻana o ka maʻi genome o ka maʻi COVID-19 i ka 96% i ka cor Batavavirus like SARS a me 86% -92% i kahi corolavirus like SARS, he kumu holoholona no COVID-19." 

Ua kōkua ka Kina i hoʻokumu ʻia i kahi kumu holoholona hihiu e hōʻoluʻolu Kāhea no ka hoʻokolokolo ʻana i ka ʻO Wuhan Institute o Virology, kahi i mālama lōʻihi ʻia ai nā coronavirus holoholona a me nā genetically manipulated. Ma kahi o, nā kumuwaiwai a me nā hoʻoikaika ʻana o ka kaiāulu ʻepekema a me nā kaiaulu hana honua hauʻoli i ka hoʻomaopopo ʻana i nā kumu e hoʻopili ana i ka pilina ma waena o nā kānaka a me nā holoholona lōhiu. 

ʻO nā pepa ʻehā i nīnau ʻia Liu et al., Xiao et al. , Lam et al. a Zhang et al. ʻO nā mea ʻelua e ʻimi ʻia nei e nā luna hoʻoponopono puke ʻo Liu et al lāua ʻo Xiao et al. I ke kamaʻilio pū ʻana me nā mea kākau a me nā luna hoʻoponopono o kēlā mau pepa ʻelua, ua aʻo ʻo USRTK i nā pilikia koʻikoʻi me ka paʻi ʻia ʻana o kēlā mau aʻo ʻana, e like me kēia:    

  • Liu et al. ʻaʻole i paʻi a kaʻana like (ma ke noi ʻia ʻana) maka a / a i ʻole nalo i ka ʻikepili i ʻae ʻia nā poʻe loea e hōʻoia kūʻokoʻa i kā lākou aniani genomic.
  • Luna hoʻoponopono ma nā mea ʻelua Nature a Nā Polokalamu PLoS, a ʻo Professor Stanley Perlman, ka hoʻoponopono o Liu et al., i ʻae i nā kamaʻilio leka uila ua ʻike lākou i nā pilikia koʻikoʻi me kēia mau pepa a ke nānā nei nā puke pai iā lākou. Eia naʻe, ʻaʻole lākou i hoʻolaha i ka lehulehu i nā pilikia kūpono me nā pepa.  

ʻO ka hāmau o nā puke pai e pili ana i kā lākou mau noiʻi e hoʻomau nei, ʻo ia hoʻi ka ʻike ʻole o nā kaiāulu ākea o nā ʻepekema, a me nā lehulehu i hoʻopilikia ʻia e COVID-19 i nā pilikia e pili ana i nā pepa noiʻi, wahi a Dr. 

"Manaʻoʻiʻo mākou he mea nui kēia mau pilikia, no ka mea hiki ke hoʻohālikelike i ka pane ʻana o nā ʻoihana i kahi maʻi ahulau kūpilikiʻi i hoʻopili nui i nā ola a me nā ola ma ka honua holoʻokoʻa," i ʻōlelo ʻo ia.

Hiki ke loaʻa nā loulou i kēia mau leka uila ma aneʻi: 

Ma Iulai 2020, Ua hoʻomaka ʻo US Right to Know e waiho i nā noi moʻohelu lehulehu i ka ʻimi ʻana i ka ʻikepili mai nā hui lehulehu i ka hoʻāʻo e ʻike i nā mea i ʻike ʻia e pili ana i ke kumu o ka novel coronavirus SARS-CoV-2, ke kumu o ka maʻi Covid-19. Mai ka hoʻomaka o ka laha ma Wuhan, ua make ʻo SARS-CoV-2 ma kahi o hoʻokahi miliona mau kānaka, ʻoiai e maʻi ana he mau miliona i loko o ka maʻi ahulau e hoʻomau mau nei.

Ma Nowemapa 5, Ua waiho ʻo US Right to Know i kahi hoʻopiʻi kue i ka National Institutes of Health (NIH) no ka ʻaihue ʻana i nā ʻāpana o ke kānāwai Freedom of Information. Ke hoʻopiʻi, i waiho ʻia i ka ʻĀpana ʻApana ʻAmelika ma Wakinekona, DC, ʻimi i nā leka me a i ʻole e pili ana i nā ʻoihana e like me Wuhan Institute of Virology a me ka Wuhan Center for Disease Control and Prevent, a me ka EcoHealth Alliance, ka mea i hui pū me a kālā kālā ka Wuhan Institute o Virology.

ʻO US Right to Know kahi hui noiʻi noiʻi nonprofit e nānā ana i ka hoʻolaha ʻana i ka transparency no ke olakino lehulehu. Hiki iā 'oe kākoʻo i kā mākou noiʻi a me ka hōʻike ʻana ma o ka hāʻawi ʻana ma aneʻi.